scholarly journals The Promoter of the Human Proliferating Cell Nuclear Antigen Gene Is Not Sufficient for Cell Cycle-dependent Regulation in Organotypic Cultures of Keratinocytes

2002 ◽  
Vol 277 (19) ◽  
pp. 17271-17280 ◽  
Author(s):  
Francisco Noya ◽  
Wei-Ming Chien ◽  
Xiaoyun Wu ◽  
Nilam S. Banerjee ◽  
John C. Kappes ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Proliferating Cell Nuclear Antigen ◽  
Nuclear Antigen ◽  
Organotypic Cultures ◽  
Antigen Gene ◽  
Cycle Dependent ◽  
Proliferating Cell

Cell cycle dependent distribution of proliferating cell nuclear antigen/cyclin and cdc2-kinase in mouse T-lymphoma cells

1993 ◽  
Vol 52 (3) ◽  
pp. 362-372 ◽  
Author(s):  
David A. Brott ◽  
James D. Alvey ◽  
Michael R. Bleavins ◽  
Felix A. de la Iglesia ◽  
Narendra D. Lalwani
Keyword(s):  
Cell Cycle ◽  
Proliferating Cell Nuclear Antigen ◽  
Nuclear Antigen ◽  
Cdc2 Kinase ◽  
Lymphoma Cells ◽  
T Lymphoma Cells ◽  
T Lymphoma ◽  
Cycle Dependent ◽  
Proliferating Cell

Demonstration of cell cycle kinetics in thyroid primary culture by immunostaining of proliferating cell nuclear antigen: differences in cyclic AMP-dependent and -independent mitogenic stimulations

1993 ◽  
Vol 105 (1) ◽  
pp. 69-80 ◽  
Author(s):  
M. Baptist ◽  
J.E. Dumont ◽  
P.P. Roger
Keyword(s):  
Cell Cycle ◽  
Dna Synthesis ◽  
Primary Culture ◽  
Proliferating Cell Nuclear Antigen ◽  
Cell Cycle Progression ◽  
Nuclear Antigen ◽  
Major Influence ◽  
Cell Cycle Kinetics ◽  
Experimental Conditions ◽  
Proliferating Cell

In this study, experimental conditions are described that allowed us to follow the fate of the DNA polymerase delta-associated proliferating cell nuclear antigen (PCNA), by immunolabeling during the overall cell cycle. Differences in subcellular localization or the presence of PCNA allowed us to identify each phase of the cell cycle. Using these cell cycle markers in dog thyroid epithelial cells in primary culture, we found unexpected differences in cell cycle kinetics, in response to stimulations through cAMP-dependent and cAMP-independent pathways. These provide a new dimension to the view that the two pathways are largely separate, but co-operate on DNA synthesis initiation. More precisely, thyrotropin (TSH), acting via cAMP, exerts a potent triggering effect on DNA synthesis, associated with a precocious induction of PCNA appearance. This constitutes the major influence of TSH (cAMP) in determining cell cycle progression, which is only partly moderated by TSH-dependent lengthening of S- and G2-phases.

scholarly journals Proliferating Cell Nuclear Antigen as the Cell Cycle Sensor for an HLA-Derived Peptide Blocking T Cell Proliferation

2000 ◽  
Vol 164 (12) ◽  
pp. 6188-6192 ◽  
Author(s):  
Xuefeng Ling ◽  
Salar Kamangar ◽  
Michelle L. Boytim ◽  
Zvi Kelman ◽  
Philip Huie ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Cell Proliferation ◽  
T Cell ◽  
Proliferating Cell Nuclear Antigen ◽  
Nuclear Antigen ◽  
T Cell Proliferation ◽  
Proliferating Cell

scholarly journals Activation of the Mouse Proliferating Cell Nuclear Antigen Gene Promoter by Adenovirus Type 12 E1A Proteins

1992 ◽  
Vol 83 (6) ◽  
pp. 609-617 ◽  
Author(s):  
Masamitsu Yamaguchi ◽  
Yuko Hayashi ◽  
Fumiko Hirose ◽  
Shuhei Matsuoka ◽  
Kazuko Shiroki ◽  
...  
Keyword(s):  
Proliferating Cell Nuclear Antigen ◽  
Gene Promoter ◽  
Adenovirus Type ◽  
Nuclear Antigen ◽  
Antigen Gene ◽  
Proliferating Cell
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