scholarly journals Microsomal Triglyceride Transfer Protein Binding and Lipid Transfer Activities Are Independent of Each Other, but Both Are Required for Secretion of Apolipoprotein B Lipoproteins from Liver Cells

2001 ◽  
Vol 276 (30) ◽  
pp. 28606-28612 ◽  
Author(s):  
Jun-shan Liang ◽  
Henry N. Ginsberg
Keyword(s):  
Protein Binding ◽  
Apolipoprotein B ◽  
Microsomal Triglyceride Transfer Protein ◽  
Liver Cells ◽  
Lipid Transfer ◽  
Transfer Protein

Development and Physiological Regulation of Intestinal Lipid Absorption. I. Development of intestinal lipid absorption: cellular events in chylomicron assembly and secretion

2007 ◽  
Vol 293 (3) ◽  
pp. G519-G524 ◽  
Author(s):  
Dennis D. Black
Keyword(s):  
Dietary Fat ◽  
Apolipoprotein B ◽  
Microsomal Triglyceride Transfer Protein ◽  
Lipid Absorption ◽  
Cellular Mechanisms ◽  
Peripheral Tissues ◽  
Physiological Regulation ◽  
Transfer Protein ◽  
Cellular Events ◽  
Apolipoprotein A

The newborn mammal must efficiently absorb dietary fat, predominantly as triacylglycerol, and produce chylomicrons to deliver this lipid to peripheral tissues. The cellular mechanisms involved in enterocyte chylomicron assembly have recently been elucidated, and data on their regulation in the immature gut are beginning to emerge. This review focuses on key proteins involved in chylomicron assembly: apolipoprotein B-48, microsomal triglyceride transfer protein, and apolipoproten A-IV. Recent studies support a role for apolipoprotein A-IV in enhancing chylomicron secretion by promoting production of larger particles. These proteins are regulated in a manner to maximize the lipid absorptive capacity of the newborn intestine.

scholarly journals Apolipoprotein B-containing lipoprotein assembly in microsomal triglyceride transfer protein-deficient McA-RH7777 cells

2010 ◽  
Vol 51 (8) ◽  
pp. 2253-2264 ◽  
Author(s):  
Yanwen Liu ◽  
Medha Manchekar ◽  
Zhihuan Sun ◽  
Paul E. Richardson ◽  
Nassrin Dashti
Keyword(s):  
Apolipoprotein B ◽  
Microsomal Triglyceride Transfer Protein ◽  
Transfer Protein ◽  
Lipoprotein Assembly

scholarly journals Genes for Apolipoprotein B and Microsomal Triglyceride Transfer Protein Are Expressed in the Heart

Circulation ◽  
1998 ◽  
Vol 98 (1) ◽  
pp. 13-16 ◽  
Author(s):  
Lars B. Nielsen ◽  
Murielle Véniant ◽  
Jan Borén ◽  
Martin Raabe ◽  
Jinny S. Wong ◽  
...  
Keyword(s):  
Apolipoprotein B ◽  
Microsomal Triglyceride Transfer Protein ◽  
Transfer Protein
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