G Protein-coupled Receptor Kinase 6A Phosphorylates the Na+/H+Exchanger Regulatory Factor via a PDZ Domain-mediated Interaction

Randy A. Hall; Robert F. Spurney; Richard T. Premont; Nadeem Rahman; Jeremy T. Blitzer; Julie A. Pitcher; Robert J. Lefkowitz

doi:10.1074/jbc.274.34.24328

G Protein-coupled Receptor Kinase 6A Phosphorylates the Na+/H+Exchanger Regulatory Factor via a PDZ Domain-mediated Interaction

Journal of Biological Chemistry ◽

10.1074/jbc.274.34.24328 ◽

1999 ◽

Vol 274 (34) ◽

pp. 24328-24334 ◽

Cited By ~ 106

Author(s):

Randy A. Hall ◽

Robert F. Spurney ◽

Richard T. Premont ◽

Nadeem Rahman ◽

Jeremy T. Blitzer ◽

...

Keyword(s):

G Protein ◽

Pdz Domain ◽

Receptor Kinase ◽

Regulatory Factor ◽

G Protein Coupled Receptor ◽

G Protein Coupled

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Sorting Nexin 27 Protein Regulates Trafficking of a p21-activated Kinase (PAK) Interacting Exchange Factor (β-Pix)-G Protein-coupled Receptor Kinase Interacting Protein (GIT) Complex via a PDZ Domain Interaction

Journal of Biological Chemistry ◽

10.1074/jbc.m111.260802 ◽

2011 ◽

Vol 286 (45) ◽

pp. 39403-39416 ◽

Cited By ~ 30

Author(s):

Julie L. Valdes ◽

Jingrong Tang ◽

Mark I. McDermott ◽

Jean-Cheng Kuo ◽

Seth P. Zimmerman ◽

...

Keyword(s):

G Protein ◽

Pdz Domain ◽

Receptor Kinase ◽

G Protein Coupled Receptor ◽

Domain Interaction ◽

Interacting Protein ◽

Sorting Nexin ◽

Exchange Factor ◽

P21 Activated Kinase ◽

G Protein Coupled

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Phosphorylation of the Platelet-derived Growth Factor Receptor-β by G Protein-coupled Receptor Kinase-2 Reduces Receptor Signaling and Interaction with the Na+/H+ Exchanger Regulatory Factor

Journal of Biological Chemistry ◽

10.1074/jbc.m403274200 ◽

2004 ◽

Vol 279 (40) ◽

pp. 41775-41782 ◽

Cited By ~ 33

Author(s):

Kerry L. Hildreth ◽

Jiao-Hui Wu ◽

Larry S. Barak ◽

Sabrina T. Exum ◽

Luke K. Kim ◽

...

Keyword(s):

Growth Factor ◽

G Protein ◽

Growth Factor Receptor ◽

Platelet Derived Growth Factor ◽

Receptor Signaling ◽

Receptor Kinase ◽

Regulatory Factor ◽

G Protein Coupled Receptor ◽

G Protein Coupled

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Faculty Opinions recommendation of Keeping G proteins at bay: a complex between G protein-coupled receptor kinase 2 and Gbetagamma.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1013646.191521 ◽

2003 ◽

Author(s):

Patricia C Weber

Keyword(s):

G Protein ◽

G Proteins ◽

Receptor Kinase ◽

G Protein Coupled Receptor ◽

G Protein Coupled

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Faculty Opinions recommendation of Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726271231.793520213 ◽

2016 ◽

Author(s):

Miles Congreve ◽

Mark Pickworth

Keyword(s):

G Protein ◽

Biological Evaluation ◽

Receptor Kinase ◽

G Protein Coupled Receptor ◽

Design Synthesis ◽

G Protein Coupled ◽

Synthesis And Biological Evaluation

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Faculty Opinions recommendation of Structure-Based Design of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors Based on Paroxetine.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.727435636.793530013 ◽

2017 ◽

Author(s):

John Lowe

Keyword(s):

G Protein ◽

Receptor Kinase ◽

G Protein Coupled Receptor ◽

G Protein Coupled

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Effects of Chinese herbal medicine Tianqi Pingchan Granule on G protein-coupled receptor kinase 6 involved in the prevention of levodopa-induced dyskinesia in rats with Parkinson disease

Journal of Chinese Integrative Medicine ◽

10.3736/jcim20120911 ◽

2012 ◽

pp. 1018-1024 ◽

Cited By ~ 1

Author(s):

N Wu

Keyword(s):

Herbal Medicine ◽

Parkinson Disease ◽

G Protein ◽

Chinese Herbal Medicine ◽

Receptor Kinase ◽

G Protein Coupled Receptor ◽

Chinese Herbal ◽

G Protein Coupled

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G Protein-Coupled Receptor Kinase 2 - a Feedback Regulator of Gq Pathway Signalling

Current Drug Targets - Immune Endocrine & Metabolic Disorders ◽

10.2174/1568005310101020139 ◽

2001 ◽

Vol 1 (2) ◽

pp. 139-151 ◽

Cited By ~ 4

Author(s):

J. Theilade ◽

S. Haunso ◽

S. Sheikh

Keyword(s):

G Protein ◽

Receptor Kinase ◽

G Protein Coupled Receptor ◽

G Protein Coupled ◽

Feedback Regulator

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Molecular cloning and expression of GRK6. A new member of the G protein-coupled receptor kinase family.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)36546-9 ◽

1993 ◽

Vol 268 (26) ◽

pp. 19521-19527 ◽

Cited By ~ 1

Author(s):

J.L. Benovic ◽

J Gomez

Keyword(s):

Molecular Cloning ◽

G Protein ◽

Cloning And Expression ◽

Receptor Kinase ◽

G Protein Coupled Receptor ◽

Kinase Family ◽

G Protein Coupled

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Structural Determinants Influencing the Potency and Selectivity of Indazole-Paroxetine Hybrid G Protein–Coupled Receptor Kinase 2 Inhibitors

Molecular Pharmacology ◽

10.1124/mol.117.110130 ◽

2017 ◽

Vol 92 (6) ◽

pp. 707-717 ◽

Cited By ~ 10

Author(s):

Renee Bouley ◽

Helen V. Waldschmidt ◽

M. Claire Cato ◽

Alessandro Cannavo ◽

Jianliang Song ◽

...

Keyword(s):

G Protein ◽

Receptor Kinase ◽

G Protein Coupled Receptor ◽

Structural Determinants ◽

G Protein Coupled

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Expression, purification, and characterization of the G protein-coupled receptor kinase GRK5.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)42226-5 ◽

1994 ◽

Vol 269 (2) ◽

pp. 1099-1105 ◽

Cited By ~ 8

Author(s):

P. Kunapuli ◽

J.J. Onorato ◽

M.M. Hosey ◽

J.L. Benovic

Keyword(s):

G Protein ◽

Receptor Kinase ◽

G Protein Coupled Receptor ◽

Purification And Characterization ◽

G Protein Coupled

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