Distribution and comparative anatomy of cutaneous glands in certain Marsupials.

1963 ◽  
Vol 11 (2) ◽  
pp. 250 ◽  
Author(s):  
LMA Green
Keyword(s):  
Comparative Anatomy ◽  
External Auditory Meatus ◽  
Mammary Glands ◽  
Sweat Glands ◽  
Histological Structure ◽  
Trichosurus Vulpecula ◽  
Sebaceous Glands ◽  
Sminthopsis Crassicaudata ◽  
Large Compound ◽  
Eccrine Sweat Glands

An account is given of the histological structure of the cutaneous glands of the four species of marsupials, Trichosurus vulpecula, Dromicia concinna, Isoodon obesulus, and Sminthopsis crassicaudata. The types of glands described comprise the eccrine sweat glands of non-hairy skin and the apocrine sweat and sebaceous glands usually associated with hairs. Also included in the survey are the more specialized glands of the sternal and interscapular regions as well as the apocrine and sebaceous glands present in the skin lining the marsupium. The histology of the nipples is also given but, as the mammary glands of marsupials are regarded as being similar to those of other mammals, no account of them has been presented. The glands of Harder and, in marsupials, the less frequently occuring lacrimal gland are described with other glands of the ocular region. The cerumen-producing glands of the external auditory meatus include apocrine tubules and large compound sebaceous glands; the histology of both types is given. The less well-known glands of the cloacal region are described in some detail. These glands comprise two main varieties: a holocrine sebaceous type (which produces an oily secretion) and another structure, somewhat similar histologically, which liberates cells into the glandular lumen.

scholarly journals HISTOLOGY AND CYTOCHEMISTRY OF HUMAN SKIN. XV. SITES OF PHOSPHORYLASE AND AMYLO-1,6-GLUCOSIDASE ACTIVITY

1958 ◽  
Vol 6 (3) ◽  
pp. 201-207 ◽  
Author(s):  
RICHARD A. ELLIS ◽  
WILLIAM MONTAGNA
Keyword(s):  
Human Skin ◽  
External Auditory Meatus ◽  
Hair Follicles ◽  
The Body ◽  
Sweat Glands ◽  
Sebaceous Glands ◽  
Glucosidase Activity ◽  
Stratum Spinosum ◽  
Peripheral Cells ◽  
Eccrine Sweat Glands

The localization of phosphorylase and amylo-1,6-glucosidase activity has been studied in surgical specimens of human skin from the palm, sole, axilla, external auditory meatus, and other representative regions of the body. With few exceptions these enzymes are found in cells which are known to contain glycogen normally. The epidermis shows some variability, but amylo-1,6-glucosidase is generally present in the stratum spinosum, while phosphorylase is found in both the stratum basale and the stratum spinosum. The relative amounts of the enzymes vary with the thickness of the epidermis and with the age of the donor. Growing hair follicles have abundant phosporylase and amylo-1,6-glucosidase in their outer root sheaths, while resting ones contain only phosphorylase. A short portion of the epidermal duct of the eccrine sweat glands has no enzymatic activity, but the remainder of the duct and the secretory portion of the gland is richer in phosphorylase than any other structure of the skin. The apocrine sweat glands have neither enzyme in their secretory coils, but the duct of these glands is rich in phosphorylase. Time sebaceous glands contain both enzymes, but phosphorylase is more concentrated in the peripheral cells of the gland. Neither the centers of the glands nor the sebum contain either enzyme.

Freeze-Fracture Examination of Tight Junctions of Human Eccrine Sweat Glands

1980 ◽  
Vol 38 ◽  
pp. 634-635
Author(s):  
J. V. Briggman ◽  
J. Bigelow ◽  
H. Bank ◽  
S. S. Spicer
Keyword(s):  
Cystic Fibrosis ◽  
Freeze Fracture ◽  
Sweat Glands ◽  
Hypertonic Solution ◽  
Dark Cells ◽  
Clear Cells ◽  
Junctional Complexes ◽  
Secretory Coil ◽  
Eccrine Sweat Glands ◽  
Eccrine Sweat

The prevalence of strands shown by freeze-fracture in the zonula occludens of junctional complexes is thought to correspond closely with the transepi-thelial electrical resistance and with the tightness of the junction and its obstruction to paracellular flow.1 The complexity of the network of junc¬tional complex strands does not appear invariably related to the degree of tightness of the junction, however, as rabbit ileal junctions have a complex network of strands and are permeable to lanthanum. In human eccrine sweat glands the extent of paracellular relative to transcellular flow remains unknown, both for secretion of the isotonic precursor fluid by the coil and for resorption of a hypertonic solution by the duct. The studies reported here undertook, therefore, to determine with the freeze-fracture technique the complexity of the network of ridges in the junctional complexes between cells in the secretory coil and the sweat ducts. Glands from a patient with cystic fibrosis were also examined because an alteration in junctional strands could underlie the decreased Na+ resorption by sweat ducts in this disease. Freeze-fracture replicas were prepared by standard procedures on isolated coil and duct segments of human sweat glands. Junctional complexes between clear cells, between dark cells and between clear and dark cells on the main lumen, and between clear cells on intercellular canaliculi of the coil con¬tained abundant anastomosing closely spaced strands averaging 6.4 + 0.7 (mean + SE) and 9.0 +0.5 (Fig. 1) per complex, respectively. Thus, the junctions in the intercellular canaliculi of the coil appeared comparable in complexity to those of tight epithlia. Occasional junctions exhibited, in addition, 2 to 5 widely spaced anastomosing strands in a very close network basal to the compact network. The fewer junctional complexes observed thus far between the superficial duct cells consisted on the average of 6 strands arranged in a close network and 1 to 4 underlying strands that lay widely separated from one another (Fig. 2). The duct epitelium would, thus, be judged slightly more "leaky" than the coil. Infrequent junctional complexes observed to date in the secretory coil segment of a cystic fibrosis specimen disclosed rela¬tively few closely crowded strands.

scholarly journals Inflammatory Skin Lesions in Three SARS-CoV-2 Swab-Negative Adolescents: A Possible COVID-19 Sneaky Manifestation?

2021 ◽  
Vol 13 (2) ◽  
pp. 181-188
Author(s):  
Giuseppe Ingravallo ◽  
Francesco Mazzotta ◽  
Leonardo Resta ◽  
Sara Sablone ◽  
Gerardo Cazzato ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Respiratory Symptoms ◽  
Clinical Manifestations ◽  
Skin Lesions ◽  
Sweat Glands ◽  
Histological Findings ◽  
Immune Mediated ◽  
Nodular Lesions ◽  
Immunohistochemical Evidence ◽  
Eccrine Sweat Glands

Coronavirus disease 19 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is associated with various clinical manifestations, including skin lesions. In particular, during the COVID-19 pandemic lock-down period numerous chilblain-like lesions, mainly located on the feet, were observed in adolescents. The latter were often asymptomatic or associated with very mild respiratory symptoms. Here, we report three cases of acral nodular lesions in SARS-CoV-2 swab-negative adolescents with histological findings of chronic immune-mediated inflammation and immunohistochemical evidence of SARS-CoV-2 spike glycoproteins in endothelial cells and eccrine sweat glands. In one of these cases, the virus presence was confirmed by electron microscopy.

scholarly journals Training of Eccrine Sweat Glands in Paraplegics

1970 ◽  
Vol 54 (3) ◽  
pp. 229-232 ◽  
Author(s):  
Becky B. Johnson ◽  
Robert E. Johnson
Keyword(s):  
Sweat Glands ◽  
Eccrine Sweat Glands ◽  
Eccrine Sweat

Tufted angioma associated with hyperplasia of eccrine sweat glands

2017 ◽  
Vol 42 (5) ◽  
pp. 548-550
Author(s):  
Y. Saito ◽  
Y. Shimomura ◽  
R. Abe
Keyword(s):  
Sweat Glands ◽  
Tufted Angioma ◽  
Eccrine Sweat Glands ◽  
Eccrine Sweat

Pharmacologic responsiveness of isolated single eccrine sweat glands

1981 ◽  
Vol 240 (1) ◽  
pp. R44-R51 ◽  
Author(s):  
K. Sato ◽  
F. Sato
Keyword(s):  
Dose Response ◽  
Dissociation Constants ◽  
Sweat Rate ◽  
Sweat Glands ◽  
Adrenergic Agonist ◽  
Beta Adrenergic ◽  
Adrenergic Agents ◽  
Eccrine Sweat Glands ◽  
Eccrine Sweat

Pharmacologic responsiveness of the eccrine sweat gland has never been studied under well-defined in vitro experimental conditions. Using isolated cannulated single monkey palm eccrine sweat glands, the dose response to both cholinergic and alpha- and beta-adrenergic agents and the effects of various antagonists on agonists were studied. The maximal sweat rate was highest after stimulation with cholinergic agonists, was lower with the beta-adrenergic agonist, and was least with the alpha-adrenergic agonist. Each secretory response was inhibited by its specific antagonist. Attempts to demonstrate the spare receptor, if any, by means of preincubation of the glands with N-(2-chlorethyl)dibenzylamine (Dibenamine) were unsuccessful. From the hyperbolic dose-response curves the values for KA and KB, dissociation constants for agonists and antagonists, respectively, were thus tentatively estimated according to Clark's classical receptor theory. Schild plots for each agonist-antagonist interaction produced straight lines with slopes of near unity, indicating the adequacy of the methodology. It was concluded that the isolated eccrine sweat glands retain their pharmacologic viability in vitro and show responsiveness to cholinergic as well as both alpha- and beta-adrenergic stimulations.

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