Nutrition and fetal growth

1995 ◽  
Vol 7 (3) ◽  
pp. 539 ◽  
Author(s):  
JE Harding ◽  
BM Johnston
Keyword(s):  
Fetal Growth ◽  
Minor Component ◽  
Building Blocks ◽  
Tissue Growth ◽  
Maternal Undernutrition ◽  
Substrate Supply ◽  
Key Factor ◽  
A Minor ◽  
Substrate Deprivation

Nutrient supply to the fetus is a key factor in the regulation of fetal growth. However, the direct supply of nutrients to provide building blocks for tissue growth is likely to be only a minor component of this regulation. The indirect effects of nutrition on fetal endocrine and metabolic status, and on the interaction between the fetus, placenta and mother all of which must be coordinated to allow fetal growth are also important. Maternal undernutrition may alter the growth of the fetus and its different component tissues in a way which cannot be explained solely on the basis of reduced substrate supply during the rapid growth phase of the tissues involved. Adaptation to altered substrate supply, during both undernutrition and refeeding, involves sequential changes in the metabolic and endocrine interactions between the fetus and the placenta. In addition, undernutrition has long-term consequences for the fetus. There is evidence for nutritional programming of fetal endocrine and cardiovascular systems before birth. Nutritional effects may also persist over more than one generation. The effects of nutrition on fetal growth are far more complex than simply those of substrate deprivation.

Disaccharidase Deficiency

1985 ◽  
Vol 7 (3) ◽  
pp. 67-75
Author(s):  
Martin H. Ulshen
Keyword(s):  
Small Intestine ◽  
Minor Component ◽  
Building Blocks ◽  
Cow Milk ◽  
Milk Formula ◽  
First Year ◽  
Caloric Content ◽  
Dietary Component ◽  
A Minor ◽  
First Year Of Life

Disaccharidases are enzymes of the small intestine, and they are essential for normal carbohydrate digestion. Carbohydrates are an important dietary component, providing about half of the calories in a typical Western diet. The smallest carbohydrate units, the monosaccharides, are the building blocks for more complex sugars and starches. The monosaccharides of dietary importance include glucose, galactose, and fructose. Carbohydrates are present in an average diet, primarily in the form of dissacharides (two monosaccharides linked together) and starches (glucose polymers). The disaccharide lactose is the major carbohydrate in milk and accounts for about 40% of the caloric content of human milk as well as commercial cow milk formula. Lactose is composed of the monosaccharides glucose and galactose; sucrose is composed of glucose and fructose. During the first year of life, juices and solids are introduced into the diet in increasing amounts and, therefore, sucrose and starches provide an increasing proportion of the dietary calories. By the adult years, about 50% of dietary carbohydrate is ingested in the form of starch, and lactose is often a minor component of the diet. Among the dietary carbohydrates, only the monosaccharides can be transported intact across the luminal surface of the small intestine. The moroe complex carbohydrates must undergo digestion prior to assimilation.

scholarly journals Long Term Monitoring in Switzerland Reveals That Adalia bipunctata Strongly Declines in Response to Harmonia axyridis Invasion

Insects ◽  
2020 ◽  
Vol 11 (12) ◽  
pp. 883
Author(s):  
Marc Kenis ◽  
Saidou Nacambo ◽  
Johan Van Vlaenderen ◽  
Renate Zindel ◽  
René Eschen
Keyword(s):  
Harmonia Axyridis ◽  
Control Function ◽  
Minor Component ◽  
Adalia Bipunctata ◽  
Ecological Niches ◽  
Long Term Monitoring ◽  
A Minor ◽  
The Impact ◽  
Term Monitoring

A long-term monitoring was conducted at 40 sites in four different habitats in north-western Switzerland to observe changes in populations of native ladybirds, following the invasion of the Asian harlequin ladybird, Harmonia axyridis. From 2006 to 2017, the same trees and meadows were sampled at least seven times per year using standard protocols. On 15 broadleaved hedges, H. axyridis quickly became the dominant species, representing 60 to 80% of adult ladybirds collected. It was second in abundance at five pine (Pinus sylvestris) stands and was a minor component of the ladybird complex at five spruce (Picea abies) stands and in 15 meadows. This survey revealed the severe decline of Adalia bipunctata, which was the most abundant native ladybird on broadleaved trees in 2006–2009 and has almost disappeared since 2010. So far, other native ladybirds do not seem to decline significantly, including species occupying the same ecological niches as H. axyridis. The total number of aphidophagous ladybirds did not decline either, suggesting that the biological control function of ladybirds on aphids living in these habitats has not been affected by the arrival of H. axyridis. Recommendations are given to further assess the impact of H. axyridis on native ladybirds and aphids.

scholarly journals Long-term supplementation with selenate and selenomethionine: urinary excretion by New Zealand women

1997 ◽  
Vol 77 (4) ◽  
pp. 551-563 ◽  
Author(s):  
Marion F. Robinson ◽  
Christine D. Thomson ◽  
Christopher P. Jenkinson ◽  
Gu Luzhen ◽  
Philip D Whanger
Keyword(s):  
New Zealand ◽  
Urinary Excretion ◽  
Minor Component ◽  
Double Blind Trial ◽  
Double Blind ◽  
Close Relationship ◽  
Glomerular Filtrate ◽  
Renal Clearances ◽  
A Minor

Thirty-six New Zealand women aged between 18 and 23 years received daily for 32 weeks, 200 µg Se as Se-enriched yeast (selenomethionine, SeMet), or brewer's yeast mixed with selenate, or no added Se (placebo) in a double-blind trial. Mean daily Se excretion increased with both supplements; the selenate group excreted more than the SeMet group, 123v. 66 µg/d respectively at week 2, equivalent to 57v. 27 % of the dose. Thereafter Se output increased for the SeMet group reaching a plateau at about 100 µg/d at week 16, when plasma Se had also plateaued at 190 ng/ml. The selenate group had reached an earlier plateau of 110 ng Se/ml at week 7. There was a close relationship between 24 h urine and plasma Se for the SeMet group but not for the selenate group. Renal plasma clearances showed two distinctly different responses; the clearance of 0·4 ml/min reached by the SeMet group at week 2 plateaued as plasma Se increased almost 2-fold; whereas for the selenate group the clearance varied between 0·8 and 1·1 ml/min whilst plasma Se remained almost constant at 110 ng/ml. Previous studies, also of 200 µgSe/d as Se-rich bread, in New Zealand (NZ) and elsewhere showed similar responses to Se-yeast; the selenite response was intermediate between selenate and Se-yeast (SeMet). The full significance of these studies awaits identification of Se components in plasma, glomerular filtrate and urine; meanwhile renal clearances serve as a pointer to changes in the distribution of Se-containing fractions in the plasma. Trimethylselenonium was detected in basal urines, and was a minor component in urines of supplemented NZ subjects at about 1 % of the total Se.

scholarly journals Tiefer See – a key site for lake sediment research in NE Germany

2019 ◽  
Vol 2 ◽  
pp. 89-93 ◽  
Author(s):  
Achim Brauer ◽  
Markus J. Schwab ◽  
Brian Brademann ◽  
Sylvia Pinkerneil ◽  
Martin Theuerkauf
Keyword(s):  
Algal Blooms ◽  
Environmental Changes ◽  
Minor Component ◽  
Last Glaciation ◽  
Sediment Research ◽  
Ne Germany ◽  
History Of ◽  
A Minor ◽  
Sedimentation Processes

Abstract. Tiefer See formed in a subglacial gully system at the end of the last glaciation in the northeast German lowlands. The lake has been selected as a focus site within the TERENO (Terrestrial Environmental Observatory) NE German observatory because it forms annual laminations (calcite varves) providing detailed information of past climate and environmental changes. Our research integrates palaeolimnology and limnology by combining high-resolution analyses of the sediment record with a comprehensive monitoring of the lake and its sedimentation processes since 2012. This allows evaluation of the observed effects of ongoing climate change in the context of the long-term history of the lake. The lacustrine sediment profile comprises the last 13 000 years and is dated by a multiple dating approach. The sedimentation is dominated by biochemical calcite formation and algal blooms. Detrital material from the catchment forms only a minor component even during times of increased human impact. Repeated changes between well-varved, poorly varved and homogeneous sediment intervals indicate that sedimentation processes in the lake are particularly sensitive to changes in lake circulation. The research at Tiefer See is embedded in ICLEA (https://www.iclea.de, last access: 2 August 2019) and BaltRap (https://www.io-warnemuende.de/projekt/167/baltrap.html, last access: 2 August 2019) projects.

scholarly journals Endocrine mechanisms of intrauterine programming

Reproduction ◽  
2004 ◽  
Vol 127 (5) ◽  
pp. 515-526 ◽  
Author(s):  
A L Fowden ◽  
A J Forhead
Keyword(s):  
Growth Factors ◽  
Fetal Growth ◽  
Fetal Development ◽  
Experimental Studies ◽  
In Utero ◽  
Tissue Growth ◽  
Postnatal Life ◽  
Organ Systems ◽  
Intrauterine Programming

Epidemiological findings and experimental studies in animals have shown that individual tissues and whole organ systems can be programmedin uteroduring critical periods of development with adverse consequences for their function in later life. Detailed morphometric analyses of the data have shown that certain patterns of intrauterine growth, particularly growth retardation, can be related to specific postnatal outcomes. Since hormones regulate fetal growth and the development of individual fetal tissues, they have a central role in intrauterine programming. Hormones such as insulin, insulin-like growth factors, thyroxine and the glucocorticoids act as nutritional and maturational signals and adapt fetal development to prevailing intrauterine conditions, thereby maximizing the chances of survival bothin uteroand at birth. However, these adaptations may have long-term sequelae. Of the hormones known to control fetal development, it is the glucocorticoids that are most likely to cause tissue programmingin utero. They are growth inhibitory and affect the development of all the tissues and organ systems most at risk of postnatal pathophysiology when fetal growth is impaired. Their concentrationsin uteroare also elevated by all the nutritional and other challenges known to have programming effects. Glucocorticoids act at cellular and molecular levels to alter cell function by changing the expression of receptors, enzymes, ion channels and transporters. They also alter various growth factors, cytoarchitectural proteins, binding proteins and components of the intracellular signalling pathways. Glucocorticoids act, directly, on genes and, indirectly, through changes in the bioavailability of other hormones. These glucocorticoid-induced endocrine changes may be transient or persist into postnatal life with consequences for tissue growth and development both before and after birth. In the long term, prenatal glucocorticoid exposure can permanently reset endocrine systems, such as the somatotrophic and hypothalamic–pituitary–adrenal axes, which, in turn, may contribute to the pathogenesis of adult disease. Endocrine changes may, therefore, be both the cause and the consequence of intrauterine programming.

Attachment of oral bacteria to titanium surfaces: An SEM study

1994 ◽  
Vol 52 ◽  
pp. 468-469
Author(s):  
J. E. Laffoon ◽  
R. L. Anderson ◽  
J. C. Keller ◽  
C. D. Wu-Yuan
Keyword(s):  
Technical Problem ◽  
Titanium Implant ◽  
Oral Bacteria ◽  
Bacterial Cells ◽  
Thin Sections ◽  
Surface Ultrastructure ◽  
Sem Study ◽  
Key Factor ◽  
Titanium Surfaces

Titanium (Ti) dental implants have been used widely for many years. Long term implant failures are related, in part, to the development of peri-implantitis frequently associated with bacteria. Bacterial adherence and colonization have been considered a key factor in the pathogenesis of many biomaterial based infections. Without the initial attachment of oral bacteria to Ti-implant surfaces, subsequent polymicrobial accumulation and colonization leading to peri-implant disease cannot occur. The overall goal of this study is to examine the implant-oral bacterial interfaces and gain a greater understanding of their attachment characteristics and mechanisms. Since the detailed cell surface ultrastructure involved in attachment is only discernible at the electron microscopy level, the study is complicated by the technical problem of obtaining titanium implant and attached bacterial cells in the same ultra-thin sections. In this study, a technique was developed to facilitate the study of Ti implant-bacteria interface.Discs of polymerized Spurr’s resin (12 mm x 5 mm) were formed to a thickness of approximately 3 mm using an EM block holder (Fig. 1). Titanium was then deposited by vacuum deposition to a film thickness of 300Å (Fig. 2).

INTRAUTERINE GROWTH RETARDATION - A REVIEW ARTICLE

2018 ◽  
pp. 184-195
Author(s):  
Minh Son Pham ◽  
Vu Quoc Huy Nguyen ◽  
Dinh Vinh Tran
Keyword(s):  
Fetal Growth ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Fetal Growth Restriction ◽  
Growth Restriction ◽  
Growth Potential ◽  
National Guidelines ◽  
Intrauterine Growth ◽  
No Gold Standard

Small for gestational age (SGA) and fetal growth restriction (FGR) is difficult to define exactly. In this pregnancy condition, the fetus does not reach its biological growth potential as a consequence of impaired placental function, which may be because of a variety of factors. Fetuses with FGR are at risk for perinatal morbidity and mortality, and poor long-term health outcomes, such as impaired neurological and cognitive development, and cardiovascular and endocrine diseases in adulthood. At present no gold standard for the diagnosis of SGA/FGR exists. The first aim of this review is to: summarize areas of consensus and controversy between recently published national guidelines on small for gestational age or fetal growth restriction; highlight any recent evidence that should be incorporated into existing guidelines. Another aim to summary a number of interventions which are being developed or coming through to clinical trial in an attempt to improve fetal growth in placental insufficiency. Key words: fetal growth restriction (FGR), Small for gestational age (SGA)

Designing a CRM Framework for online & offline sports footwear retailers

2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Rodrigo Cueva ◽  
Guillem Rufian ◽  
Maria Gabriela Valdes
Keyword(s):  
Environmental Changes ◽  
Customer Relationship ◽  
Business Strategies ◽  
Economic Sectors ◽  
Running Shoes ◽  
Brick And Mortar ◽  
Key Factor ◽  
On Line ◽  
The Impact

The use of Customer Relationship Managers to foster customers loyalty has become one of the most common business strategies in the past years.  However, CRM solutions do not fill the abundance of happily ever-after relationships that business needs, and each client’s perception is different in the buying process.  Therefore, the experience must be precise, in order to extend the loyalty period of a customer as much as possible. One of the economic sectors in which CRM’s have improved this experience is retailing, where the personalized attention to the customer is a key factor.  However, brick and mortar experiences are not enough to be aware in how environmental changes could affect the industry trends in the long term.  A base unified theoretical framework must be taken into consideration, in order to develop an adaptable model for constructing or implementing CRMs into companies. Thanks to this approximation, the information is complemented, and the outcome will increment the quality in any Marketing/Sales initiative. The goal of this article is to explore the different factors grouped by three main domains within the impact of service quality, from a consumer’s perspective, in both on-line and off-line retailing sector.  Secondly, we plan to go a step further and extract base guidelines about previous analysis for designing CRM’s solutions focused on the loyalty of the customers for a specific retailing sector and its product: Sports Running Shoes.

Protonation effects on dynamic flux properties of aqueous metal complexes

2009 ◽  
Vol 74 (10) ◽  
pp. 1543-1557 ◽  
Author(s):  
Herman P. Van Leeuwen ◽  
Raewyn M. Town
Keyword(s):  
Complex Formation ◽  
Metal Ion ◽  
Good Description ◽  
Minor Component ◽  
Outer Sphere ◽  
Metal Species ◽  
Central Metal ◽  
Inner Sphere ◽  
A Minor ◽  
Protonated Ligand

The degree of (de)protonation of aqueous metal species has significant consequences for the kinetics of complex formation/dissociation. All protonated forms of both the ligand and the hydrated central metal ion contribute to the rate of complex formation to an extent weighted by the pertaining outer-sphere stabilities. Likewise, the lifetime of the uncomplexed metal is determined by all the various protonated ligand species. Therefore, the interfacial reaction layer thickness, μ, and the ensuing kinetic flux, Jkin, are more involved than in the conventional case. All inner-sphere complexes contribute to the overall rate of dissociation, as weighted by their respective rate constants for dissociation, kd. The presence of inner-sphere deprotonated H2O, or of outer-sphere protonated ligand, generally has a great impact on kd of the inner-sphere complex. Consequently, the overall flux can be dominated by a species that is a minor component of the bulk speciation. The concepts are shown to provide a good description of experimental stripping chronopotentiometric data for several protonated metal–ligand systems.

Sign in / Sign up

Export Citation Format

Share Document