Bovine theileriosis in Australia: a decade of disease

2018 ◽  
Vol 39 (4) ◽  
pp. 215 ◽  
Author(s):  
Cheryl Jenkins
Keyword(s):  
East Coast ◽  
Clinical Disease ◽  
Diverse Range ◽  
Theileria Orientalis ◽  
The Past ◽  
Wildlife Species ◽  
Sequencing Studies ◽  
Cattle Herds ◽  
Bovine Theileriosis ◽  
Theileria Spp

Theileriosis refers to the clinical disease caused by organisms from the genus Theileria, tick-borne haemoprotozoans infecting a diverse range of mammalian hosts. In Australia, Theileria spp. have been identified in both domestic and wildlife species but the bovine parasite, Theileria orientalis, has received the most attention due to the emergence and spread of clinical disease over the past 12 years, particularly in cattle herds on the east coast. At an estimated $20million per annum, the burden to cattle production is significant but despite over a decade of disease, there are still no effective chemotherapeutic treatments or vaccines available in Australia. Recent insights from genome sequencing studies reveal species level diversity within T. orientalis, which may help direct efforts at disease control.

scholarly journals Genetic Diversity of Bovine Hemoprotozoa in South Korea

Pathogens ◽  
2020 ◽  
Vol 9 (9) ◽  
pp. 768
Author(s):  
Dongmi Kwak ◽  
Min-Goo Seo
Keyword(s):  
South Korea ◽  
Clinical Symptoms ◽  
Surface Protein ◽  
18S Rrna Gene ◽  
Rrna Gene ◽  
Theileria Orientalis ◽  
Bovine Theileriosis ◽  
Major Piroplasm Surface Protein ◽  
Theileria Spp ◽  
Epidemiological Information

Tick-borne pathogens cause economically significant diseases in cattle. Theileria spp. are parasitic protozoa and the causative agent of bovine theileriosis. Here we report the distribution and risk factors of bovine Theileria using blood samples taken between 2018 and 2019. Of 737 tested cattle, nine animals (1.2%) were positive for Theileria orientalis infection by 18S rRNA gene amplification. Further analysis of the infected samples using the T. orientalis major piroplasm surface protein (MPSP) gene revealed five different genotypes circulating in the population: Types 1, 2, 3, 7, and N3. To the best of our knowledge, this is the first research to describe the existence of the T. orientalis MPSP genotype N3 in South Korea. Although the prevalence of bovine T. orientalis was low, our study offers data on the geographical distribution and prevalence of bovine Theileria spp. in South Korea. Further studies are warranted to determine the correlation of clinical symptoms with parasite MPSP genotypes. Our data provide epidemiological information to help control bovine theileriosis in South Korea.

Theileria orientalis MPSP types in Australian cattle herds associated with outbreaks of clinical disease and their association with clinical pathology findings

2013 ◽  
Vol 191 (3-4) ◽  
pp. 209-217 ◽  
Author(s):  
Graeme J. Eamens ◽  
Jocelyn R. Gonsalves ◽  
Cheryl Jenkins ◽  
Damian Collins ◽  
Graham Bailey
Keyword(s):  
Clinical Pathology ◽  
Clinical Disease ◽  
Theileria Orientalis ◽  
Cattle Herds

Nine Centuries of Man

2017 ◽  
Keyword(s):  
Twentieth Century ◽  
Diverse Range ◽  
Gender Expectations ◽  
Court Records ◽  
The Past ◽  
Wide Range ◽  
Police Reports ◽  
Late Twentieth ◽  
Scottish History ◽  
Late Twentieth Century

What did it mean to be a man in Scotland over the past nine centuries? Scotland, with its stereotypes of the kilted warrior and the industrial ‘hard man’, has long been characterised in masculine terms, but there has been little historical exploration of masculinity in a wider context. This interdisciplinary collection examines a diverse range of the multiple and changing forms of masculinities from the late eleventh to the late twentieth century, exploring the ways in which Scottish society through the ages defined expectations for men and their behaviour. How men reacted to those expectations is examined through sources such as documentary materials, medieval seals, romances, poetry, begging letters, police reports and court records, charity records, oral histories and personal correspondence. Focusing upon the wide range of activities and roles undertaken by men – work, fatherhood and play, violence and war, sex and commerce – the book also illustrates the range of masculinities that affected or were internalised by men. Together, the chapters illustrate some of the ways Scotland’s gender expectations have changed over the centuries and how, more generally, masculinities have informed the path of Scottish history

scholarly journals Current Strategies for Noble Metal Nanoparticle Synthesis

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Giyaullah Habibullah ◽  
Jitka Viktorova ◽  
Tomas Ruml
Keyword(s):  
Noble Metal ◽  
Noble Metals ◽  
Drug Carriers ◽  
Industrial Applications ◽  
Metal Nanoparticle ◽  
Noble Metal Nanoparticles ◽  
Synthesis Methods ◽  
Gold And Silver Nanoparticles ◽  
Diverse Range ◽  
The Past

AbstractNoble metals have played an integral part in human history for centuries; however, their integration with recent advances in nanotechnology and material sciences have provided new research opportunities in both academia and industry, which has resulted in a new array of advanced applications, including medical ones. Noble metal nanoparticles (NMNPs) have been of great importance in the field of biomedicine over the past few decades due to their importance in personalized healthcare and diagnostics. In particular, platinum, gold and silver nanoparticles have achieved the most dominant spot in the list, thanks to a very diverse range of industrial applications, including biomedical ones such as antimicrobial and antiviral agents, diagnostics, drug carriers and imaging probes. In particular, their superior resistance to extreme conditions of corrosion and oxidation is highly appreciated. Notably, in the past two decades there has been a tremendous advancement in the development of new strategies of more cost-effective and robust NMNP synthesis methods that provide materials with highly tunable physicochemical, optical and thermal properties, and biochemical functionalities. As a result, new advanced hybrid NMNPs with polymer, graphene, carbon nanotubes, quantum dots and core–shell systems have been developed with even more enhanced physicochemical characteristics that has led to exceptional diagnostic and therapeutic applications. In this review, we aim to summarize current advances in the synthesis of NMNPs (Au, Ag and Pt).

scholarly journals Chronic Myelomonocytic Leukemia—Hematopathology Perspective

2021 ◽  
Author(s):  
Siba El Hussein ◽  
Sa A. Wang ◽  
Naveen Pemmaraju ◽  
Joseph D. Khoury ◽  
Sanam Loghavi
Keyword(s):  
Risk Stratification ◽  
Large Scale ◽  
Chronic Myelomonocytic Leukemia ◽  
Clinical Implications ◽  
The Past ◽  
Genomic Landscape ◽  
Sequencing Studies ◽  
Myelomonocytic Leukemia ◽  
Insight Into

ABSTRACT Our understanding of chronic myelomonocytic leukemia (CMML) has evolved tremendously over the past decade. Large-scale sequencing studies have led to increased insight into the genomic landscape of CMML and clinical implications of these changes. This in turn has resulted in refined and improved risk stratification models, which to date remain versatile and subject to remodeling, as new and evolving studies continue to refine our understanding of this disease. In this article, we present an up-to-date review of CMML from a hematopathology perspective, while providing a clinically practical summary that sheds light on the constant evolution of our understanding of this disease.

scholarly journals Late Holocene temperature variability in Tasmania inferred from borehole temperature data

2017 ◽  
Vol 13 (6) ◽  
pp. 559-572 ◽  
Author(s):  
Asadusjjaman Suman ◽  
Fiona Dyer ◽  
Duanne White
Keyword(s):  
East Coast ◽  
Past Century ◽  
Borehole Data ◽  
Depth Profiles ◽  
The Past ◽  
North East ◽  
The North ◽  
Borehole Temperature ◽  
Temperature Depth

Abstract. Thirty-six borehole temperature–depth profiles were analysed to reconstruct the ground surface temperature history (GSTH) of eastern Tasmania for the past 5 centuries. We used the singular value decomposition method to invert borehole temperatures to produce temperature histories. The quality of borehole data was classified as high or low based on model misfit. The quality of the borehole data was not dependent on topography or land use. Analysis reveals that three to five high-quality borehole temperature–depth profiles were adequate to reconstruct robust paleotemperature records from any area. Average GSTH reconstructed from Tasmanian boreholes shows temperature increases about 1.2 ± 0.2 °C during the past 5 centuries. Reconstructed temperatures were consistent with meteorological records and other proxy records from Tasmania during their period of overlap. Temperature changes were greatest around the north-east coast and decreased towards the centre of Tasmania. The extension of the East Australian Current (EAC) further south and its strengthening around the north-east coast of Tasmania over the past century was considered a prime driver of warmer temperatures observed in north-east Tasmania.

Two Historical Archaeological Periods in Florida

1948 ◽  
Vol 13 (4Part1) ◽  
pp. 313-319 ◽  
Author(s):  
Hale G. Smith
Keyword(s):  
East Coast ◽  
Archaeological Survey ◽  
Jefferson County ◽  
Late Period ◽  
The Past ◽  
New Period ◽  
Park Service ◽  
Georgia Coast

In the past year through excavations of sites and examination of various collections, there have appeared elements in a late context that do not follow or conform to the archaeological traditions known for Florida up to this time. On the east coast the collections of material excavated by W. J. Winter gave us new data on the late period around St. Augustine and its cultural affiliations to the Georgia coast. This has been named the St. Augustine Period. In the excavation of a Spanish mission site3 in Jefferson County by the Archaeological Survey of the Florida Park Service there appeared elements sufficiently different in time and content to name a new period the Leon-Jefferson.Here follows a discussion and summary of the characteristics of the two periods.

scholarly journals Diagnostic Testing for Zika Virus: a Postoutbreak Update

2018 ◽  
Vol 56 (4) ◽  
Author(s):  
Elitza S. Theel ◽  
D. Jane Hata
Keyword(s):  
Drug Administration ◽  
Zika Virus ◽  
Food And Drug Administration ◽  
Diagnostic Testing ◽  
Clinical Disease ◽  
Diagnostic Assays ◽  
Molecular Assays ◽  
The Past ◽  
The U.S

ABSTRACT Since the emergence and dissemination of Zika virus (ZIKV) in late 2015, our understanding of the biology, transmission, clinical disease, and potential sequelae associated with infection has markedly expanded. Over the past 2 years, the number of diagnostic assays for ZIKV has increased from none in 2015 to 5 serological assays and 14 molecular assays in 2017, all with emergency use authorization granted through the U.S. Food and Drug Administration. Here we provide an update on ZIKV, addressing what we have collectively learned since the outbreak began, including a summary of currently available diagnostic assays for this virus.

Bombay Before Mumbai

2019 ◽  
Keyword(s):  
Urban Communities ◽  
South Asian ◽  
Urban History ◽  
Historical Writing ◽  
Diverse Range ◽  
The Public ◽  
The Past ◽  
Public Imagination ◽  
The City

‘City of Gold’, ‘Urbs Prima in Indis’, ‘Maximum City’: no Indian metropolis has captivated the public imagination quite like Mumbai. The past decade has seen an explosion of historical writing on the city that was once Bombay. This book, featuring new essays by its finest historians, presents a rich sample of Bombay’s palimpsestic pasts. It considers the making of urban communities and spaces, the workings of power and the nationalist makeover of the colonial city. In addressing these themes, the contributors to this volume engage critically with the scholarship of a distinguished historian of this frenetic metropolis. For over five decades, Jim Masselos has brought to life with skill and empathy Bombay’s hidden histories. His books and essays have traversed an extraordinarily diverse range of subjects, from the actions of the city’s elites to the struggles of its most humble denizens. His pioneering research has opened up new perspectives and inspired those who have followed in his wake. Bombay Before Mumbai is a fitting tribute to Masselos’ enduring contribution to South Asian urban history

scholarly journals Diversity and origins of anaerobic metabolism in mitochondria and related organelles

2015 ◽  
Vol 370 (1678) ◽  
pp. 20140326 ◽  
Author(s):  
Courtney W. Stairs ◽  
Michelle M. Leger ◽  
Andrew J. Roger
Keyword(s):  
Metabolic Pathways ◽  
Anaerobic Metabolism ◽  
Low Oxygen ◽  
Metabolic Potential ◽  
Free Living ◽  
Eukaryotic Diversity ◽  
The Past ◽  
Microbial Eukaryotes ◽  
Sequencing Studies ◽  
Diversity Of Life

Across the diversity of life, organisms have evolved different strategies to thrive in hypoxic environments, and microbial eukaryotes (protists) are no exception. Protists that experience hypoxia often possess metabolically distinct mitochondria called mitochondrion-related organelles (MROs). While there are some common metabolic features shared between the MROs of distantly related protists, these organelles have evolved independently multiple times across the breadth of eukaryotic diversity. Until recently, much of our knowledge regarding the metabolic potential of different MROs was limited to studies in parasitic lineages. Over the past decade, deep-sequencing studies of free-living anaerobic protists have revealed novel configurations of metabolic pathways that have been co-opted for life in low oxygen environments. Here, we provide recent examples of anaerobic metabolism in the MROs of free-living protists and their parasitic relatives. Additionally, we outline evolutionary scenarios to explain the origins of these anaerobic pathways in eukaryotes.

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