Failure of antisomatostatin antibodies to stimulate the growth of crossbred lambs

1988 ◽  
Vol 28 (2) ◽  
pp. 161 ◽  
Author(s):  
RM Hoskinson ◽  
P Djura ◽  
RJ Welch ◽  
BE Harrison ◽  
GH Brown ◽  
...  
Keyword(s):  
Antibody Response ◽  
Antibody Titre ◽  
Growth Promotion ◽  
Freund’S Complete Adjuvant ◽  
Freund's Complete Adjuvant ◽  
Response Profile

The effect of antisomatostatin antibodies on the growth of crossbred female and wether lambs was studied over 8 months. The antibody response profile established in the immune lambs, following a sequence of 3 vaccinations with an immunogenic somatostatin-haemocyanin conjugate in Freund's complete adjuvant, reached a maximum mean antisomatostatin antibody titre of 1:11 400. There were no effects (P>0.05) of the treatment on liveweight or shoulder height of immune lambs. There were predictable overall effects due to sex but not to level of antibody titre within the immunisation treatment. These data indicate circumstances where immunological growth promotion does not result when antisomatostatin antibodies are raised in growing crossbred lambs that are typical of a commercial breed.

Humoral antibody response to cattle to formalinized Staphylococcus aureus vaccine

1975 ◽  
Vol 21 (11) ◽  
pp. 1756-1759
Author(s):  
T. K. S. Mukkur ◽  
Usha J. Tewari
Keyword(s):  
Staphylococcus Aureus ◽  
Antibody Response ◽  
Post Partum ◽  
Post Inoculation ◽  
Freund’S Complete Adjuvant ◽  
Humoral Antibody ◽  
Freund's Complete Adjuvant ◽  
Agglutination Titer

Five cows were inoculated intradermally with formalinized Staphylococcus aureus suspension in Freund's complete adjuvant and the development of the humoral antibody response was followed as judged by the agglutination titer of sera, at various intervals post inoculation. Highest titers were observed at 78–87 days post inoculation. Agglutinating activity was found in IgM and IgG fractions (IgG1 and IgG2) of both serum and colostrum. The agglutinating activity of colostrum was significantly higher at 12 than at 24 and 36 h, post partum. However, no such activity was detected in either normal cow serum or colostrum against S. aureus.

Immune Response of Juvenile Coho Salmon (Oncorhynchus kisutch) to Aeromonas salmonicida Cells Administered Intraperitoneally in Freund's Complete Adjuvant

1974 ◽  
Vol 31 (11) ◽  
pp. 1751-1755 ◽  
Author(s):  
W. D. Paterson ◽  
J. L. Fryer
Keyword(s):  
Immune Response ◽  
Antibody Response ◽  
Protective Immunity ◽  
Coho Salmon ◽  
Oncorhynchus Kisutch ◽  
Aeromonas Salmonicida ◽  
Homogeneous Population ◽  
Freund’S Complete Adjuvant ◽  
Freund's Complete Adjuvant ◽  
Single Vaccination

The antibody response of a population of juvenile coho salmon (Oncorhynchus kisutch) held at 12 C approached 100% following a single parenteral vaccination with Aeromonas salmonicida cells emulsified in Freund's complete adjuvant. This response indicates that coho salmon behave as a homogeneous population with respect to immunological competence.Fish as small as 1.2 g produced antibodies as early as 4 wk after administration of this vaccine; high levels of antibody persisted for at least 1 yr after injection. This single vaccination provided juvenile coho salmon with protective immunity against furunculosis.

Experimental Amyloidosis Induced by Immune Complex

1971 ◽  
Vol 29 ◽  
pp. 582-583
Author(s):  
A. Kawaoi
Keyword(s):  
Immune Complex ◽  
Systemic Amyloidosis ◽  
Human Diseases ◽  
Experimental Amyloidosis ◽  
Freund’S Complete Adjuvant ◽  
Freund's Complete Adjuvant ◽  
Immunological Approach ◽  
Experimentally Induced

Numbers of immunological approach have been made to the amyloidosis through the variety of predisposing human diseases and the experimentally induced animals by the greater number of agents. The results suggest an important role of impaired immunity involving both humoral and cell-mediated aspects.Recently the author has succeeded in producing amyloidosis in the rabbits and mice by the injections of immune complex of heat denatured DNA.The aim of this report is to demonstrate the details of the ultrastructure of the amyloidosis induced by heterologous insoluble immune complex. Eleven of twelve mice, dd strain, subcutaneously injected twice a week with Freund's complete adjuvant and four of seven animals intraperitonially injected developed systemic amyloidosis two months later from the initial injections. The spleens were electron microscopically observed.

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