Influence of some digestive processes on the digestion by cattle of cereal grain fed whole

1978 ◽  
Vol 18 (90) ◽  
pp. 29 ◽  
Author(s):  
PC Toland
Keyword(s):  
Particle Size ◽  
Cereal Grains ◽  
Lower Percentage ◽  
Whole Grain ◽  
Wheat Grain ◽  
Wheat Varieties ◽  
Hard Wheat ◽  
Cereal Grain ◽  
Size Index

Pen studies were conducted with cattle in which the digestibility, rate of fermentation, site of digestion and grain loss in faeces were measured in diets comprising 4.8 kg of one or other of four cereal grains together with 2.4 kg of pasture hay. The cereals were Avon oats, Swan oats, Olympic wheat and Emblem wheat with natural weights of 48.3, 60.5, 81.3 and 78.8 kg hl-1 and particle size index 24, 35, 31 and 14, respectively. The apparent in vivo digestibility of Avon and Swan oats of 71.9 and 74.6 did not differ significantly (P > 0.05). However, there was significantly less grain cracked during initial mastication (12.5 vs. 19.2 per cent and a lower percentage of grain voided in faeces (4.3 vs. 9.3) for Avon compared with Swan oats (P < 0.05). The in vivo digestibility of wheat grain was significantly higher for Olympic than for Emblem (77.5 vs. 72.6 per cent) ;these performances were accompanied by lower percentages of grain cracked during initial mastication (17.0 vs. 22.3) and less whole grain DM voided in faeces (14.6 vs. 18.4 per cent) for Olympic compared with Emblem (P < 0.05). The major difference in the digestion of oat and wheat varieties was that rumination accounted for a high proportion of the breakdown of oat grain whereas the wheat varieties were digested by rumen fermentation with only a small proportion of grains broken down by rumination. The breakdown of whole grain in rumination was important for all rations. For the light oats, heavy oats, soft wheat and hard wheat, rumination accounted for 66 per cent, 44 per cent, 27 per cent and 17 per cent of the total breakdown respectively.

Influence of a gene causing hardness on the milling and baking quality of two wheats

1969 ◽  
Vol 20 (6) ◽  
pp. 971 ◽  
Author(s):  
KJ Symes
Keyword(s):  
Particle Size ◽  
Genetic Background ◽  
Loaf Volume ◽  
Near Isogenic Lines ◽  
Simple Process ◽  
Hard Wheat ◽  
Baking Quality ◽  
Handling Characteristics ◽  
Size Index

Near-isogenic lines of Falcon, a hard wheat with good baking quality and high milling extraction, and Heron, a soft wheat of medium baking quality and rather low milling extraction, were produced differing only in the gene which determines hardness as measured by the particle size index. It is shown that the superiority of Falcon in milling extraction, loaf texture, and dough handling characteristics is very strongly associated with the gene which causes it to be a hard wheat. While Falcon generally has a loaf volume superior to that of Heron, if the genetic background of two wheats is identical except for hardness, soft wheats have higher loaf volumes. Because these three variables, which largely constitute total loaf score, are not all favoured by the same particle size index, total loaf score is less clearly influenced by hardness. Nevertheless hard wheats are always superior to, or not significantly different from, soft wheats of the same pedigree in this respect. This work points out the difficulty of producing really good quality soft wheats but on the other hand shows that soft wheats can easily be improved in at least some features of baking quality by the simple process of making them hard.

scholarly journals Cereal Grain Classification by Optimal Features and Intelligent Classifiers

2010 ◽  
Vol 5 (4) ◽  
pp. 506 ◽  
Author(s):  
Ali Douik ◽  
Mehrez Abdellaoui
Keyword(s):  
Cereal Grains ◽  
Classification Methods ◽  
Hard Wheat ◽  
Cereal Grain ◽  
Wavelet Features ◽  
Different Types ◽  
Grain Classification

The present paper focused on the classification of cereal grains using different classifiers combined to morphological, colour and wavelet features. The grain types used in this study were Hard Wheat, Tender Wheat and Barley. Different types of features (morphological, colour and wavelet) were extracted from colour images using different approaches. They were applied to different classification methods.

Classification of Australian wheat varieties based on the granularity of their wholemeal

1961 ◽  
Vol 1 (1) ◽  
pp. 18 ◽  
Author(s):  
KJ Symes
Keyword(s):  
Particle Size ◽  
Environmental Factors ◽  
Moisture Content ◽  
Protein Level ◽  
The Other ◽  
Original Sample ◽  
Wheat Varieties ◽  
Size Index ◽  
Australian Wheat

A simple and accurate test for determining the granularity of wheat wholemeal is described. Ten grams of wheat are ground, sieved for five minutes and the amount passing through the sieve is expressed as a percentage of the original sample and recorded as the particle size index. Particle size index is shown to be a varietal character that divides Australian varieties into two distinct groups. As all typical hard varieties fall into one of these groups and all typical soft varieties into the other group, particle size index is suggested as the most satisfactory criterion for designating these categories. Variations in protein level and moisture content do influence the particle size index, without in any way invalidating the test. The effect of changes in these environmental factors, on particle size index, varies from variety to variety both in degree and direction.

Loss of starch and fibre of whole grain in nylon bags suspended in the rumen of steers

1979 ◽  
Vol 92 (1) ◽  
pp. 243-245 ◽  
Author(s):  
P. C. Toland
Keyword(s):  
Chemical Composition ◽  
Dry Matter ◽  
Alimentary Tract ◽  
Rumen Fermentation ◽  
Cereal Grains ◽  
Whole Grain ◽  
Cereal Grain

Several investigations (Shaw & Norton, 1906; Darnell & Copeland, 1936; Kimberley, 1976) have reported no appreciable loss of nutrients of unbroken grain voided by cattle. Although the chemical composition of voided whole grain may be similar to the grain as fed, losses in grain dry matter ranging from 10 to 26% for cereal grains passing through the alimentary tract of steers have been measured (Toland, 1976, 1978a, 6). In one of these studies (Toland, 19786) the disappearance of grain dry matter of whole oats and wheat in nylon bags suspended in the rumen for 48 h was approximately 20 and 35 % respectively. Further analyses of this dry matter remaining in the nylon bags for 48 and 96 h of incubation would indicate which components of the grain were being broken down in rumen fermentation. This report provides information on the differential loss of the fibre and starch components of the grain dry matter from incubation in nylon bags for the two varieties each of oats and wheat and for an additional cereal grain, triticale.

The inheritance of grain hardness in wheat as measured by the particle size index

1965 ◽  
Vol 16 (2) ◽  
pp. 113 ◽  
Author(s):  
KJ Symes
Keyword(s):  
Particle Size ◽  
Major Gene ◽  
Soft Wheat ◽  
Grain Hardness ◽  
Modifying Genes ◽  
Hard Wheat ◽  
Wheat Improvement ◽  
Size Index ◽  
Donor Parent ◽  
The Difference

The difference in particle size index between a hard wheat (Falcon) and a soft wheat (Heron) is shown to be due to a single major gene. Tests of F2 populations of seven other crosses between hard and soft wheats indicate that this is not uncommon. The existence of minor genes which modify the action of the major gene in determining the hardness or softness of wheat grain is also demonstrated. In at least one case (Spica) a different level of hardness appears to be due to a different major gene from that found in Falcon and not to modifying genes. The conversion of a hard wheat to a soft wheat or vice versa can be achieved by backcrossing. The grain hardness of the new wheat will be influenced both by the hardness of the donor parent and by the degree to which modifying genes are carried over. This demonstration of the simple inheritance of grain hardness as measured by particle size index is of significance to wheat improvement programmes.

Formulation and Evaluation of Nanosuspension of Simvastatin

2015 ◽  
Vol 8 (2) ◽  
pp. 2858-2873
Author(s):  
Rupali L. Shid ◽  
Shashikant N. Dhole ◽  
Nilesh Kulkarni ◽  
Santosh L Shid
Keyword(s):  
Particle Size ◽  
Zeta Potential ◽  
Factorial Design ◽  
Dissolution Rate ◽  
In Vitro Dissolution ◽  
Total Drug ◽  
23 Factorial Design ◽  
Rate Of Dissolution

Poor water solubility and slow dissolution rate are issues for the majority of upcoming and existing biologically active compounds. Simvastatin is poorly water-soluble drug and its bioavailability is very low from its crystalline form. The purpose of this study wasto increase the solubility and dissolution rate of simvastatin by the  preparation of nanosuspension by emulsification solvent diffusion method at laboratory scale. Prepared nanosus-pension was evaluated for its particle size and in vitro dissolution study and characterized by zeta potential,differential scanning calorimetry (DSC) and X-Ray diffractometry (XRD), motic digital microscopy, entrapment efficiency, total drug content, saturated solubility study and in vivo study. A 23 factorial design was employed to study the effect of independent variables, amount of SLS (X1), amount of PVPK-30 (X2) and poloxamer-188 (X3) and dependent variables are total drug content and polydispersity Index. The obtained results showed that particle size (nm) and rate of dissolution has been improved when nanosuspension prepared with the higherconcentration of PVPK-30 with the higher concentration of PVP K-30 and Poloxamer-188 and lower concentration of SLS. The particle size and zeta potential of optimized formulation was found to be 258.3 nm and 23.43. The rate of dissolution of the optimized nanosuspension was enhanced (90% in 60min), relative to plain simvastatin  (21% in 60 min), mainly due to the formation of nanosized particles. These results indicate the suitability of 23 factorial  design for preparation of simvastatin loaded nano-suspension significantly improved in vitro dissolution rate and thus possibly enhance fast onset of therapeutic drug effect. In vivo study shows increase in bioavailability in nanosuspension formulation than the plain simvastatin drug.

scholarly journals Investigating the Feasibility of Mefenamic Acid Nanosuspension for Pediatric Delivery: Preparation, Characterization, and Role of Excipients

Processes ◽  
2021 ◽  
Vol 9 (4) ◽  
pp. 574
Author(s):  
Nikhat Perween ◽  
Sultan Alshehri ◽  
T. S. Easwari ◽  
Vivek Verma ◽  
Md. Faiyazuddin ◽  
...  
Keyword(s):  
Particle Size ◽  
Mefenamic Acid ◽  
Hydroxypropyl Methylcellulose ◽  
Sodium Dodecyl ◽  
Aqueous Solubility ◽  
Oral Route ◽  
Precipitation Method ◽  
Antisolvent Precipitation

Molecules with poor aqueous solubility are difficult to formulate using conventional approaches and are associated with many formulation delivery issues. To overcome these obstacles, nanosuspension technology can be one of the promising approaches. Hence, in this study, the feasibility of mefenamic acid (MA) oral nanosuspension was investigated for pediatric delivery by studying the role of excipients and optimizing the techniques. Nanosuspensions of MA were prepared by adopting an antisolvent precipitation method, followed by ultrasonication with varying concentrations of polymers, surfactants, and microfluidics. The prepared nanosuspensions were evaluated for particle size, morphology, and rheological measures. Hydroxypropyl methylcellulose (HPMC) with varying concentrations and different stabilizers including Tween® 80 and sodium dodecyl sulfate (SLS) were used to restrain the particle size growth of the developed nanosuspension. The optimized nanosuspension formula was stable for more than 3 weeks and showed a reduced particle size of 510 nm with a polydispersity index of 0.329. It was observed that the type and ratio of polymer stabilizers were responsive on the particle contour and dimension and stability. We have developed a biologically compatible oral nanoformulation for a first-in-class drug beautifully designed for pediatric delivery that will be progressed toward further in vivo enabling studies. Finally, the nanosuspension could be considered a promising carrier for pediatric delivery of MA through the oral route with enhanced biological impact.

scholarly journals Lightening Effect of Skin Lightening Cream Containing Piper betle L. Extract in Human Volunteers

Cosmetics ◽  
2021 ◽  
Vol 8 (2) ◽  
pp. 32
Author(s):  
Sharifah Shakirah Syed Omar ◽  
Hazrina Hadi ◽  
Nadzira Mohd Hanif ◽  
Hawa Mas Azmar Ahmad ◽  
Shiow-Fern Ng
Keyword(s):  
Particle Size ◽  
Zeta Potential ◽  
Human Subjects ◽  
Skin Barrier ◽  
Skin Tone ◽  
In Vivo Studies ◽  
Piper Betle ◽  
Melanin Content ◽  
Skin Lightening

Hyperpigmentation affects people globally with negative psychological impacts. Piper betle L. leaf (PBL) extract has many benefits including skin lightening which may reduce hyperpigmentation. The objective of this study was to develop an effective skin-lightening cream containing PBL with ideal characteristics. A formulation of base cream and PBL cream was prepared and characterized by centrifugation, particle size and zeta potential analysis, rheological profile studies and physical properties’ observation. In vivo studies on 30 human subjects tested the effects of base and PBL cream on skin-lightening, hydration, trans-epidermal water loss (TEWL) and elasticity through weekly tests 4 weeks in duration. Base and PBL creams had a non-Newtonian property with acceptable color, odor, texture, zeta potential, particle size and showed no phase separation. The in vivo study indicated a significant reduction in melanin content and an improvement in skin tone for PBL cream but not in base cream. TEWL and elasticity also showed significant reduction for both formulations, indicating a healthier skin barrier and supple skin with consistent use, although hydration fluctuated with no significant changes. The developed PBL cream showed significant results in the reduction in melanin content and improving skin tone, which shows the formulation can confer skin-lightening effect.

Cereal grain digestion by selected strains of ruminal fungi

1993 ◽  
Vol 39 (4) ◽  
pp. 367-376 ◽  
Author(s):  
T. A. McAllister ◽  
Y. Dong ◽  
L. J. Yanke ◽  
H. D. Bae ◽  
K.-J. Cheng ◽  
...  
Keyword(s):  
Corn Starch ◽  
Fungal Growth ◽  
Wheat Starch ◽  
Cereal Grains ◽  
Starch Granules ◽  
Starch Digestion ◽  
Protein Matrix ◽  
Cereal Grain ◽  
Neocallimastix Patriciarum ◽  
Grain Starch

The ruminal fungi Orpinomyces joyonii strain 19-2, Neocallimastix patriciarum strain 27, and Piromyces communis strain 22 were examined for their ability to digest cereal starch. All strains digested corn starch more readily than barley or wheat starch. Orpinomyces joyonii 19-2 exhibited the greatest propensity to digest starch in wheat and barley, whereas the digestion of these starches by N. patriciarum 27 and P. communis 22 was limited. Media ammonia concentrations were lower when fungal growth was evident, suggesting that all strains assimilate ammonia. Fungi formed extensive rhizoidal systems on the endosperm of corn, but O. joyonii 19-2 was the only strain to form such systems on the endosperm of wheat and barley. All strains penetrated the protein matrix of corn but did not penetrate starch granules. Starch granules from all three cereals were pitted, evidence of extensive digestion by extracellular amylases produced by O. joyonii 19-2. Similar pitting was observed on the surface of corn starch granules digested by N. patriciarum 27 and P. communis 22, but not on wheat and barley starch granules. The ability of ruminal fungi to digest cereal grains depends on both the strain of fungus and the type of grain. The extent to which fungi digest cereal grain in the rumen remains to be determined.Key words: ruminal fungi, cereal grain, starch digestion, ruminant.

scholarly journals In vitro and in vivo Evaluation of Ibuprofen Nanosuspensions for Enhanced Oral Bioavailability

2021 ◽  
Author(s):  
Mohsen Hedaya ◽  
Farzana Bandarkar ◽  
Aly Nada
Keyword(s):  
Particle Size ◽  
Tween 80 ◽  
Aqueous Solubility ◽  
In Vitro Dissolution ◽  
In Vivo Evaluation ◽  
Poorly Soluble ◽  
Extent Of Absorption ◽  
Better Than

Introduction: The objectives were to prepare, characterize and in vivo evaluate different ibuprofen (IBU) nanosuspensions prepared by ultra-homogenization, after oral administration to rabbits. Methods: The nanosuspensions produced by ultra-homogenization were tested and compared with a marketed IBU suspension for particle size, in vitro dissolution and in vivo absorption. Five groups of rabbits received orally 25 mg/kg of IBU nanosuspension, nanoparticles, unhomogenized suspension, marketed product and untreated suspension. A sixth group received 5 mg/kg IBU intravenously. Serial blood samples were obtained after IBU administration. Results: The formulated nanosuspensions showed significant decrease in particle size. Polyvinyl Pyrrolidone K30 (PP) was found to improve IBU aqueous solubility much better than the other tested polymers. Addition of Tween 80 (TW), in equal amount as PP (IBU: PP:TW, 1:2:2 w/w) resulted in much smaller particle size and better dissolution rate. The Cmax achieved were 14.8±1.64, 11.1±1.37, 9.01±0.761, 7.03±1.38 and 3.23±1.03 μg/ml and the tmax were 36±8.2, 39±8.2, 100±17.3, 112±15 and 105±17 min for the nanosuspension, nanoparticle, unhomogenized suspension, marketed IBU suspension and untreated IBU suspension in water, respectively. Bioavailability of the different formulations relative to the marketed suspension were the highest for nanosuspension> unhomogenized suspension> nanoparticles> untreated IBU suspension. Conclusion: IBU/PP/TW nanosuspensions showed enhanced in vitro dissolution as well as faster rate and higher extent of absorption as indicated from the higher Cmax, shorter tmax and larger AUC. The in vivo data supported the in vitro results. Nanosuspensions prepared by ultra-high-pressure-homogenization technique can be used as a good formulation strategy to enhance the rate and extent of absorption of poorly soluble drugs.

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