The Reaction of Thiols and α,ω-Dithiols With Triphenylphosphine and Diisopropyl Azodicarboxylate

1990 ◽  
Vol 43 (1) ◽  
pp. 161 ◽  
Author(s):  
D Camp ◽  
ID Jenkins
Keyword(s):  
Chain Length ◽  
Disulfide Bond ◽  
Alkyl Chain ◽  
Bond Formation ◽  
Product Distribution ◽  
Alkyl Chain Length ◽  
Disulfide Bond Formation ◽  
Reaction Conditions ◽  
Mitsunobu Reactions

α,ω-Dithiols in the presence of triphenylphosphine and diisopropyl azodicarboxylate are converted into a mixture of monomeric and polymeric disulfides. The product distribution is dependent on the alkyl chain length and the reaction conditions. In contrast to normal Mitsunobu reactions, disulfide bond formation is achieved with regeneration of triphenylphosphine. The mechanism of this reaction is discussed.

scholarly journals Silver Nanoparticles Stabilized with Phosphorus-Containing Heterocyclic Surfactants: Synthesis, Physico-Chemical Properties, and Biological Activity Determination

Nanomaterials ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1883
Author(s):  
Martin Pisárčik ◽  
Miloš Lukáč ◽  
Josef Jampílek ◽  
František Bilka ◽  
Andrea Bilková ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Biological Activity ◽  
Zeta Potential ◽  
Chain Length ◽  
Alkyl Chain ◽  
Chemical Properties ◽  
Alkyl Chain Length ◽  
Microbial Pathogens ◽  
Physico Chemical ◽  
Phosphorus Containing

Phosphorus-containing heterocyclic cationic surfactants alkyldimethylphenylphospholium bromides with the alkyl chain length 14 to 18 carbon atoms were used for the stabilization of silver nanodispersions. Zeta potential of silver nanodispersions ranges from +35 to +70 mV, which indicates the formation of stable silver nanoparticles (AgNPs). Long-chain heptadecyl and octadecyl homologs of the surfactants series provided the most intensive stabilizing effect to AgNPs, resulting in high positive zeta potential values and smaller diameter of AgNPs in the range 50–60 nm. A comparison with non-heterocyclic alkyltrimethylphosphonium surfactants of the same alkyl chain length showed better stability and more positive zeta potential values for silver nanodispersions stabilized with heterocyclic phospholium surfactants. Investigations of biological activity of phospholium-capped AgNPs are represented by the studies of antimicrobial activity and cytotoxicity. While cytotoxicity results revealed an increased level of HepG2 cell growth inhibition as compared with the cytotoxicity level of silver-free surfactant solutions, no enhanced antimicrobial action of phospholium-capped AgNPs against microbial pathogens was observed. The comparison of cytotoxicity of AgNPs stabilized with various non-heterocyclic ammonium and phosphonium surfactants shows that AgNPs capped with heterocyclic alkyldimethylphenylphospholium and non-heterocyclic triphenyl-substituted phosphonium surfactants have the highest cytotoxicity among silver nanodispersions stabilized by the series of ammonium and phosphonium surfactants.

scholarly journals Oxygen-independent disulfide bond formation in VEGF-A and CA9

2021 ◽  
pp. 100505
Author(s):  
Fiana Levitin ◽  
Sandy Che-Eun Serena Lee ◽  
Stephanie Hulme ◽  
Ryan A. Rumantir ◽  
Amy S. Wong ◽  
...  
Keyword(s):  
Disulfide Bond ◽  
Bond Formation ◽  
Disulfide Bond Formation

scholarly journals Physico-chemical and gel properties of heat-induced pasteurized liquid egg white gel: effect of alkyl chain length of alcohol

2021 ◽  
Vol 24 (1) ◽  
pp. 1229-1243
Author(s):  
Danai Charoensuk ◽  
Robert G. Brannan ◽  
Wilailuk Chaiyasit ◽  
Wanlop Chanasattru
Keyword(s):  
Chain Length ◽  
Alkyl Chain ◽  
Egg White ◽  
Alkyl Chain Length ◽  
Gel Properties ◽  
Gel Effect ◽  
Physico Chemical
Sign in / Sign up

Export Citation Format

Share Document