Photoinitiated Synthesis of Sulfides in Water

2016 ◽  
Vol 69 (8) ◽  
pp. 919 ◽  
Author(s):  
Sergio A. Rodriguez ◽  
Leandro D. Mena ◽  
Maria T. Baumgartner
Keyword(s):  
Aqueous Medium ◽  
Synthetic Route ◽  
Water As Solvent ◽  
Photoinduced Reaction ◽  
Aryl Sulfides

Herein, we report a synthetic route to obtain aryl sulfides using inexpensive and non-toxic reactants and water as solvent, that avoids the use of catalysts or heating. The photoinduced reaction between soluble substrates and a series of thiols in alkaline aqueous medium produces the corresponding sulfides in moderate to good yields.

Reaction of Coumarin Derivatives with Nucleophiles in Aqueous Medium

2008 ◽  
Vol 63 (1) ◽  
pp. 71-76 ◽  
Author(s):  
Mazaahir Kidwai ◽  
Shweta Rastogi ◽  
Keyword(s):  
Microwave Irradiation ◽  
Aqueous Medium ◽  
Reaction Times ◽  
Parallel Synthesis ◽  
Synthetic Approach ◽  
Coumarin Derivatives ◽  
Green Catalyst ◽  
Unsaturated Ketones ◽  
Water As Solvent

A series of heterocycles was synthesized by the reaction of α,β -unsaturated ketones of benzopyrans or coumarins with various nucleophiles in aqueous medium bearing two points of diversity. Compared to an identical library generated by conventional parallel synthesis, a microwaveassisted procedure dramatically decreased reaction times from hours to minutes, and yields of products and intermediates were improved remarkably. This synthetic approach is ecofriendly in nature which features water as solvent, microwave irradiation, and usage of a “green” catalyst (K2CO3).

Ruthenium-Promoted Acceptorless and Oxidant-Free Lactone Synthesis in Aqueous Medium

Synlett ◽  
2019 ◽  
Vol 30 (06) ◽  
pp. 721-725 ◽  
Author(s):  
Senthilkumar Muthaiah ◽  
Anita Bhatia ◽  
Muthukumar Kannan
Keyword(s):  
Aqueous Medium ◽  
Ruthenium Complexes ◽  
Water Soluble ◽  
Side Product ◽  
Mechanistic Studies ◽  
Hydrogen Acceptor ◽  
Water As Solvent ◽  
Lactone Synthesis

Ruthenium-catalyzed formation of lactones from diols in aqueous medium has been demonstrated. 1,3,5-Triazaphosphaadamantane (PTA) included water-soluble ruthenium complexes [RuCl2(PPh3)(2,6-Py-(CH2-PTA)2]·2Br and [RuCl2(PPh3)2(2-PyCH2PTA)]·Br in the presence of KOH were found to be efficient for the synthesis of lactones from diols. The reported synthetic protocol is green as it uses water as solvent, avoids the use of any hydrogen acceptor/oxidant, and produces hydrogen as the only side product. Mechanistic studies revealed that lactone formation involved aldehyde intermediate and followed dehydrogenative pathway.

Molecular iodine catalysed domino cyclization in aqueous medium: a simple and efficient synthetic route to 1,4-dihydropyridazines

RSC Advances ◽  
2015 ◽  
Vol 5 (65) ◽  
pp. 52355-52360 ◽  
Author(s):  
I. R. Siddiqui ◽  
Rahila Rahila ◽  
Pragati Rai ◽  
Hozeyfa Sagir ◽  
Malik A. Waseem
Keyword(s):  
Aqueous Medium ◽  
Molecular Iodine ◽  
Synthetic Route ◽  
Green Catalyst

An efficient protocol has been developed for the synthesis of dihydropyridazines using molecular iodine as green catalyst.

ChemInform Abstract: Molecular Iodine Catalyzed Domino Cyclization in Aqueous Medium: A Simple and Efficient Synthetic Route to 1,4-Dihydropyridazines.

ChemInform ◽  
2015 ◽  
Vol 46 (43) ◽  
pp. no-no
Author(s):  
I. R. Siddiqui ◽  
Rahila Rahila ◽  
Pragati Rai ◽  
Hozeyfa Sagir ◽  
Malik A. Waseem
Keyword(s):  
Aqueous Medium ◽  
Molecular Iodine ◽  
Synthetic Route

scholarly journals Novel β-cyclodextrin–eosin conjugates

2017 ◽  
Vol 13 ◽  
pp. 543-551 ◽  
Author(s):  
Gábor Benkovics ◽  
Damien Afonso ◽  
András Darcsi ◽  
Szabolcs Béni ◽  
Sabrina Conoci ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Aqueous Medium ◽  
2D Nmr ◽  
Eosin Y ◽  
Synthetic Route ◽  
2D Nmr Spectroscopy ◽  
Reaction Conditions ◽  
Amide Linkage ◽  
Eosin B ◽  
Light Excitation

Eosin B (EoB) and eosin Y (EoY), two xanthene dye derivatives with photosensitizing ability were prepared in high purity through an improved synthetic route. The dyes were grafted to a 6-monoamino-β-cyclodextrin scaffold under mild reaction conditions through a stable amide linkage using the coupling agent 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride. The molecular conjugates, well soluble in aqueous medium, were extensively characterized by 1D and 2D NMR spectroscopy and mass spectrometry. Preliminary spectroscopic investigations showed that the β-cyclodextrin–EoY conjugate retains both the fluorescence properties and the capability to photogenerate singlet oxygen of the unbound chromophore. In contrast, the corresponding β-cyclodextrin–EoB conjugate did not show either relevant emission or photosensitizing activity probably due to aggregation in aqueous medium, which precludes any response to light excitation.

Asymmetric catalytic sulfoxidation by a novel VIV8 cluster catalyst in the presence of serum albumin: a simple and green oxidation system

RSC Advances ◽  
2016 ◽  
Vol 6 (50) ◽  
pp. 44154-44162 ◽  
Author(s):  
Jie Tang ◽  
Peng-Fei Yao ◽  
Xiao-Ling Xu ◽  
Hai-Ye Li ◽  
Fu-Ping Huang ◽  
...  
Keyword(s):  
Serum Albumin ◽  
Aqueous Medium ◽  
Environmentally Friendly ◽  
Alkyl Aryl ◽  
Enantioselective Oxidation ◽  
Asymmetric Catalytic ◽  
Green Oxidation ◽  
System P ◽  
Aryl Sulfides ◽  
Oxidation System

Enantioselective oxidation of a series of alkyl aryl sulfides catalyzed by a novel VIV8 cluster is tested in an aqueous medium in the presence of serum albumin. The procedure is simple, environmentally friendly, selective, and highly reactive.

Synthesis of sulfonamides via I2-mediated reaction of sodium sulfinates with amines in an aqueous medium at room temperature

2015 ◽  
Vol 17 (3) ◽  
pp. 1400-1403 ◽  
Author(s):  
Xiaojun Pan ◽  
Jian Gao ◽  
Juan Liu ◽  
Junyi Lai ◽  
Huanfeng Jiang ◽  
...  
Keyword(s):  
Transition Metal ◽  
Aqueous Medium ◽  
Room Temperature ◽  
Metal Catalysts ◽  
Transition Metal Catalysts ◽  
Synthetic Route

A convenient and green synthetic route has been developed to synthesize sulfonamides in an aqueous medium at room temperature, without the use of transition metal catalysts and oxidants.

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