3D-Printable Biodegradable Polyester Tissue Scaffolds for Cell Adhesion

2015 ◽  
Vol 68 (9) ◽  
pp. 1409 ◽  
Author(s):  
Justin M. Sirrine ◽  
Allison M. Pekkanen ◽  
Ashley M. Nelson ◽  
Nicholas A. Chartrain ◽  
Christopher B. Williams ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Soft Tissue ◽  
Cell Attachment ◽  
Three Dimensional ◽  
Glycol Adipate ◽  
Tissue Engineering Scaffolds ◽  
Ethylene Glycol Adipate ◽  
Biodegradable Poly ◽  
Soft Tissue Engineering ◽  
Tissue Scaffolding

Additive manufacturing, or three-dimensional (3D) printing, has emerged as a viable technique for the production of vascularized tissue engineering scaffolds. In this report, a biocompatible and biodegradable poly(tri(ethylene glycol) adipate) dimethacrylate was synthesized and characterized for suitability in soft-tissue scaffolding applications. The polyester dimethacrylate exhibited highly efficient photocuring, hydrolyzability, and 3D printability in a custom microstereolithography system. The photocured polyester film demonstrated significantly improved cell attachment and viability as compared with controls. These results indicate promise of novel, printable polyesters for 3D patterned, vascularized soft-tissue engineering scaffolds.

Assessment of polyglycolic acid mesh and bioactive glass for soft-tissue engineering scaffolds

Biomaterials ◽  
2004 ◽  
Vol 25 (27) ◽  
pp. 5857-5866 ◽  
Author(s):  
Richard M. Day ◽  
Aldo R. Boccaccini ◽  
Sandra Shurey ◽  
Judith A. Roether ◽  
Alastair Forbes ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Soft Tissue ◽  
Bioactive Glass ◽  
Polyglycolic Acid ◽  
Tissue Engineering Scaffolds ◽  
Polyglycolic Acid Mesh ◽  
Soft Tissue Engineering

Polymer structure-property requirements for stereolithographic 3D printing of soft tissue engineering scaffolds

Biomaterials ◽  
2017 ◽  
Vol 140 ◽  
pp. 170-188 ◽  
Author(s):  
Ryan J. Mondschein ◽  
Akanksha Kanitkar ◽  
Christopher B. Williams ◽  
Scott S. Verbridge ◽  
Timothy E. Long
Keyword(s):  
Tissue Engineering ◽  
Soft Tissue ◽  
3D Printing ◽  
Polymer Structure ◽  
Structure Property ◽  
Tissue Engineering Scaffolds ◽  
Soft Tissue Engineering

Architecture control of three-dimensional polymeric scaffolds for soft tissue engineering. I. Establishment and validation of numerical models

2004 ◽  
Vol 71A (1) ◽  
pp. 81-89 ◽  
Author(s):  
Yang Cao ◽  
Malcolm R. Davidson ◽  
Andrea J. O'Connor ◽  
Geoffrey W. Stevens ◽  
Justin J. Cooper-White
Keyword(s):  
Tissue Engineering ◽  
Soft Tissue ◽  
Numerical Models ◽  
Three Dimensional ◽  
Polymeric Scaffolds ◽  
Soft Tissue Engineering

Preparation of three-dimensional interconnected macroporous cellulosic hydrogels for soft tissue engineering

Biomaterials ◽  
2010 ◽  
Vol 31 (32) ◽  
pp. 8141-8152 ◽  
Author(s):  
Zhilian Yue ◽  
Feng Wen ◽  
Shujun Gao ◽  
Ming Yi Ang ◽  
Pramoda K. Pallathadka ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Soft Tissue ◽  
Three Dimensional ◽  
Soft Tissue Engineering

scholarly journals Apigenin Induces Browning in White Adipocytes Mediated by VEGF-PRDM16 Signaling.

2022 ◽  
Author(s):  
Sreelekshmi Sreeku ◽  
Vinu Vijayan ◽  
Fathe Singh ◽  
Manu Sudhakar ◽  
Kiran M S
Keyword(s):  
Tissue Engineering ◽  
Soft Tissue ◽  
De Novo ◽  
Metabolic Shift ◽  
Tissue Engineering Scaffolds ◽  
White Adipocyte ◽  
White Adipocytes ◽  
Soft Tissue Engineering ◽  
Treatment Of Obesity ◽  
Endothelial Growth Factor

Abstract The white adipose tissues are metabolically inert which results in deranged biological signalling disorders resulting in obesity. Lack of vascularisation in these tissues is mainly responsible to make them metabolically inert. Not much work has been done in this direction to understand the role of angiogenesis in white adipocytes metabolism. In the present study, we evaluated the effect of angiogenic modulator in modulating the metabolism in white adipocyte. Nutraceuticals apigenin (Apg) was employed as angiogenic modulator. The results indicated that promoting angiogenesis by Apg enhanced the de novo differentiation and trans-differentiation of white adipocyte into brown like phenotype by triggering vascular endothelial growth factor A. Cross talk between endothelial and adipocytes were observed in co-culture studies. The metabolic shift in white adipocytes was observed to be due to the upregulation of PRDM16 cascade. The study provides new insights for inducing metabolic shift in white adipocytes by modulation of angiogenesis in white adipocyte to trigger browning for the treatment of obesity. Further the study opens scopes for development of medical devices for obese subjects, an area that needs to be addressed specifically with reference to soft tissue engineering as commercial soft tissue engineering scaffolds does not suit the obese patients.

Biodegradable poly(diol citrate) nanocomposite elastomers for soft tissue engineering

2007 ◽  
Vol 17 (9) ◽  
pp. 900-906 ◽  
Author(s):  
Antonio R. Webb ◽  
Vivek A. Kumar ◽  
Guillermo A. Ameer
Keyword(s):  
Tissue Engineering ◽  
Soft Tissue ◽  
Biodegradable Poly ◽  
Soft Tissue Engineering

Design and characterization of microcapsules-integrated collagen matrixes as multifunctional three-dimensional scaffolds for soft tissue engineering

2016 ◽  
Vol 62 ◽  
pp. 209-221 ◽  
Author(s):  
Loretta L. del Mercato ◽  
Laura Gioia Passione ◽  
Daniela Izzo ◽  
Rosaria Rinaldi ◽  
Alessandro Sannino ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Soft Tissue ◽  
Three Dimensional ◽  
Soft Tissue Engineering
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