Synthesis of N-Propargyl Iminosugar Scaffolds for Compound Library Generation using Click Chemistry

2010 ◽  
Vol 63 (5) ◽  
pp. 821 ◽  
Author(s):  
Brendan L. Wilkinson ◽  
Laurent F. Bornaghi ◽  
Marie Lopez ◽  
Peter C. Healy ◽  
Sally-Ann Poulsen ◽  
...  
Keyword(s):  
Click Chemistry ◽  
Functional Group ◽  
Efficient Synthesis ◽  
Compound Library ◽  
Library Development

We have developed an efficient synthesis of N-propargyl iminosugars for use in diversity-oriented library development. Through a common, crystalline intermediate both piperidine and azepane scaffolds can be prepared with an alkyne functional group, allowing for further elaboration through reaction with azides.

Efficient synthesis of diverse well-defined functional polypropylenes with high molecular weights and high functional group contents via thiol–halogen click chemistry

2015 ◽  
Vol 6 (7) ◽  
pp. 1150-1158 ◽  
Author(s):  
Xiao-Yan Wang ◽  
Yan-Guo Li ◽  
Hong-Liang Mu ◽  
Li Pan ◽  
Yue-Sheng Li
Keyword(s):  
Click Chemistry ◽  
Nucleophilic Substitution ◽  
Functional Group ◽  
Side Group ◽  
Efficient Synthesis ◽  
Molecular Weights

Originating from the reactive halogenated iPPs, diverse side-group and graft functionalized polypropylenes were synthesized via thiol–halogen nucleophilic substitution click chemistry.

An Efficient Synthesis of 2-Substituted Quinazolin-4(3H)-ones by Using Recyclable Wang Resin Supported Sulfonic Acid Catalyst

2020 ◽  
Vol 17 ◽  
Author(s):  
Kalyani K. ◽  
Srinivasa Reddy Kallam
Keyword(s):  
Sulfonic Acid ◽  
Functional Group ◽  
Acid Catalyst ◽  
Sulphonic Acid ◽  
Isatoic Anhydride ◽  
Efficient Synthesis ◽  
Wang Resin ◽  
Polymer Supported ◽  
High Yields

Abstract:: An efficient synthesis of 2-substituted Quinazolin-4(3H)-ones has been developed from isatoic anhydride with various amidoximes by using recyclable polymer supported sulphonic acid catalyst. Excellent functional group compatibil-ity and high yields are the important features of this protocol.

Highly efficient synthesis of polymer brushes with PEO and PCL as side chains via click chemistry

Polymer ◽  
2012 ◽  
Vol 53 (10) ◽  
pp. 1992-2000 ◽  
Author(s):  
Peng Zhao ◽  
Yechao Yan ◽  
Xiaoqin Feng ◽  
Lixin Liu ◽  
Chun Wang ◽  
...  
Keyword(s):  
Click Chemistry ◽  
Polymer Brushes ◽  
Side Chains ◽  
Efficient Synthesis ◽  
Highly Efficient

Cu(ii) PBS-bridged PMOs catalyzed one-pot synthesis of 1,4-disubstituted 1,2,3-triazoles in water through click chemistry

RSC Advances ◽  
2014 ◽  
Vol 4 (56) ◽  
pp. 29772-29781 ◽  
Author(s):  
Avvari N. Prasad ◽  
Benjaram M. Reddy ◽  
Eun-Young Jeong ◽  
Sang-Eon Park
Keyword(s):  
Click Chemistry ◽  
Heterogeneous Catalyst ◽  
Efficient Synthesis ◽  
One Pot ◽  
One Pot Synthesis

Efficient synthesis of 1,4-disubstituted 1,2,3-triazoles using Cu(ii)-PBS-HPMO as a heterogeneous catalyst.

Efficient Synthesis of “Star-like” Surfactants via “Click Chemistry” [3+2] Copper (I)-catalyzed Cycloaddition

2008 ◽  
Vol 27 (4) ◽  
pp. 231-237 ◽  
Author(s):  
Virginie Neto ◽  
Robert Granet ◽  
Grahame Mackenzie ◽  
Pierre Krausz
Keyword(s):  
Click Chemistry ◽  
Efficient Synthesis

Highly efficient synthesis and characterization of multiarm and miktoarm star-long-branched polymers via click chemistry

RSC Advances ◽  
2015 ◽  
Vol 5 (43) ◽  
pp. 34466-34474 ◽  
Author(s):  
Li Ma ◽  
Yichao Lin ◽  
Haiying Tan ◽  
Jun Zheng ◽  
Feng Liu ◽  
...  
Keyword(s):  
Click Chemistry ◽  
High Efficiency ◽  
Star Polymers ◽  
Branched Polymers ◽  
Synthesis And Characterization ◽  
Efficient Synthesis ◽  
Highly Efficient ◽  
Miktoarm Star ◽  
Star Copolymer

Two series of 3–12 multiarm star polymers and 4-miktoarm star copolymer of butadiene and styrene, in which the Mn of arm was higher than 20 kg mol−1, were synthesized with high efficiency (from 85.0% to 96.1%) via click chemistry.

Non-Nucleoside Building Blocks for Copper-Assisted and Copper-Free Click Chemistry for the Efficient Synthesis of RNA Conjugates

2010 ◽  
Vol 12 (23) ◽  
pp. 5410-5413 ◽  
Author(s):  
K. N. Jayaprakash ◽  
Chang Geng Peng ◽  
David Butler ◽  
Jos P. Varghese ◽  
Martin A. Maier ◽  
...  
Keyword(s):  
Click Chemistry ◽  
Building Blocks ◽  
Efficient Synthesis

One-Pot RAFT/“Click” Chemistry via Isocyanates: Efficient Synthesis of α-End-Functionalized Polymers

2012 ◽  
Vol 134 (30) ◽  
pp. 12596-12603 ◽  
Author(s):  
Guillaume Gody ◽  
Christian Rossner ◽  
John Moraes ◽  
Philipp Vana ◽  
Thomas Maschmeyer ◽  
...  
Keyword(s):  
Click Chemistry ◽  
Functionalized Polymers ◽  
Efficient Synthesis ◽  
One Pot
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