Uncatalyzed Knoevenagel Condensation in PEG-600 at Room Temperature

2008 ◽  
Vol 61 (9) ◽  
pp. 700 ◽  
Author(s):  
Babasaheb P. Bandgar ◽  
Balaji L. Korbad ◽  
Sachin A. Patil ◽  
Sunita B. Bandgar ◽  
Hemant V. Chavan ◽  
...  
Keyword(s):  
Polyethylene Glycol ◽  
Room Temperature ◽  
Knoevenagel Condensation ◽  
Active Methylene Compounds ◽  
Active Methylene ◽  
Peg 600

A rapid, efficient, and ecofriendly protocol has been developed for the Knoevenagel condensation of active methylene compounds with aromatic, aliphatic, conjugated and heteroaromatic aldehydes in polyethylene glycol-600 (PEG-600) with good to excellent yields.

Bi-functional NH2-MIL-101(Fe) for one-pot tandem photo-oxidation/Knoevenagel condensation between aromatic alcohols and active methylene compounds

2015 ◽  
Vol 5 (3) ◽  
pp. 1623-1628 ◽  
Author(s):  
Dengke Wang ◽  
Zhaohui Li
Keyword(s):  
Visible Light ◽  
Room Temperature ◽  
Knoevenagel Condensation ◽  
One Pot ◽  
Photo Oxidation ◽  
Aromatic Alcohols ◽  
Active Methylene Compounds ◽  
The One ◽  
Active Methylene

Bi-functional NH2-MIL-101(Fe) can efficiently catalyze the one-pot reaction between aromatic alcohols and active methylene compounds via a tandem photo-oxidation/Knoevenagel condensation under visible light and at room temperature.

The remarkable catalytic activity of ultra-small free-CeO2 nanoparticles in selective carbon–carbon bond formation reactions in water at room temperature

2015 ◽  
Vol 39 (7) ◽  
pp. 5350-5353 ◽  
Author(s):  
Subhash Banerjee
Keyword(s):  
Catalytic Activity ◽  
Room Temperature ◽  
Bond Formation ◽  
Ceo2 Nanoparticles ◽  
Cerium Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Reusable Catalyst ◽  
Carbon Carbon Bond ◽  
Active Methylene Compounds ◽  
Active Methylene

A simple and efficient protocol for selective bis-Michael addition and mono-allylation of active methylene compounds has been demonstrated using ultra-small size (∼5 nm) uncapped cerium oxide nanoparticles (free-CeO2 NPs) as a reusable catalyst in water at room temperature.

scholarly journals Microwave-assisted urea catalyzed Knoevenagel condensation of aldehydes with active methylene compounds

2020 ◽  
Vol 55 (2) ◽  
pp. 159-164
Author(s):  
WT Purba ◽  
PS Roy ◽  
S Jannat ◽  
SA Begum ◽  
MM Rahman
Keyword(s):  
Microwave Irradiation ◽  
Efficient Method ◽  
Knoevenagel Condensation ◽  
Efficient Catalyst ◽  
Microwave Assisted ◽  
Solvent Free Conditions ◽  
Wide Range ◽  
Active Methylene Compounds ◽  
Reaction Proceeds ◽  
Active Methylene

Rapid and efficient method for the synthesis of substituted olefins such as 2-(4-chlorophenylmethylene) malononitrile, 2-(4-hydroxyphenylmethylene) malononitrile and 2-cyano-3-(4-hydroxyphenyl) acrylamide etc under the influence of microwave irradiation are described. Urea has been utilized as an efficient catalyst for the Knoevenagel condensation of aldehydes with acidic active methylene compounds such as malononitrile, ethylcyanoacetate and cyanoacetamide to afford substituted olefins under the influence of microwave irradiation. The reaction proceeds smoothly under mild and solvent free conditions and the products are obtained in good yield. The method is applicable for a wide range of aldehydes including aromatic and heterocyclic substrates. Bangladesh J. Sci. Ind. Res.55(2), 159-164, 2020

Cellulose Supported Tetraethylenepentamine as a Catalyst for the Knoevenagel Condensation

2003 ◽  
Vol 2003 (3) ◽  
pp. 134-135 ◽  
Author(s):  
Yi-Qun Li ◽  
Mei-Yun Zhou ◽  
Xin-Ming Xu
Keyword(s):  
Knoevenagel Condensation ◽  
Active Methylene Compounds ◽  
Active Methylene

The Knoevenagel condensation of carbonyl substrates with active methylene compounds proceeds smoothly in commercial 95% ethanol and catalysed by cellulose supported tetraethylenepentamine to afford the desired products of good purity in moderate to excellent yields.

Ionic-liquid-supported 1,5,7-triazabicyclo[4.4.0]dec-5-ene — An efficient and recyclable organocatalyst for Michael addition to α,β-unsaturated ketones

2012 ◽  
Vol 90 (3) ◽  
pp. 290-297 ◽  
Author(s):  
Manoj Kumar Muthyala ◽  
Bhupender S Chhikara ◽  
Keykavous Parang ◽  
Anil Kumar
Keyword(s):  
Ionic Liquid ◽  
Michael Addition ◽  
Room Temperature ◽  
Significant Loss ◽  
Unsaturated Ketones ◽  
Ability To Act ◽  
Solvent Free Conditions ◽  
Active Methylene Compounds ◽  
Active Methylene ◽  
The Michael Addition

A novel ionic-liquid-supported 1,5,7-triazabicyclo[4.4.0]dec-5-ene (IL–TBD) was synthesized and investigated for its ability to act as an active organocatalyst in the Michael addition of active methylene compounds and thiophenols to chalcones under solvent-free conditions. The IL–TBD afforded Michael addition products in excellent yields (82%–94%) at room temperature, and it was simply recycled and reused at least five times without significant loss of catalytic activity.

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