Uncatalyzed Synthesis of β-Enamino Ketones in PEG - Water

2008 ◽  
Vol 61 (7) ◽  
pp. 552 ◽  
Author(s):  
Babasaheb P. Bandgar ◽  
Sachin A. Patil ◽  
Balaji L. Korbad ◽  
Sunita B. Bandgar ◽  
Baliram S. Hote
Keyword(s):  
Polyethylene Glycol ◽  
Aliphatic Amines ◽  
Dicarbonyl Compounds ◽  
Enamino Ketones ◽  
Excellent Yield ◽  
Peg 600

β-Enamino ketones have been synthesized in excellent yield by the reaction of aromatic or aliphatic amines with 1,3-dicarbonyl compounds in polyethylene glycol (PEG)-600–water. The PEG-600 is recycled and reused.

Dinuclear cobalt complexes supported by biphenol and binaphthol-derived bis(salicylaldimine) ligands: synthesis, characterization and catalytic application in β-enaminone synthesis from 1,3-dicarbonyl compounds and aliphatic amines

2020 ◽  
Vol 44 (35) ◽  
pp. 15109-15121
Author(s):  
Adelew Estifanos Filkale ◽  
Chandni Pathak
Keyword(s):  
Cobalt Complexes ◽  
Aliphatic Amines ◽  
Ambient Conditions ◽  
Dicarbonyl Compounds ◽  
Catalytic Application ◽  
Scaffolding Ligands

Biaryl scaffolding ligands form dicobalt clusters, which serve as efficient catalysts in enaminone synthesis under ambient conditions.

scholarly journals PERIODATE OXIDATION OF PEG–600, AN ESSENTIAL PHARMACEUTICAL POLYMER

2019 ◽  
pp. 251-256
Author(s):  
K. V. S. KOTESWARA RAO ◽  
R. VENKATA NADH ◽  
K. VENKATA RATNAM
Keyword(s):  
Polyethylene Glycol ◽  
Oxygen Atom ◽  
Temperature Dependence ◽  
Reaction Rate ◽  
Periodate Oxidation ◽  
Alkali Concentration ◽  
Rate Of Reaction ◽  
Atom Loss ◽  
Kinetics Of ◽  
Peg 600

Objective: To study the kinetics of periodate oxidation of polyethylene glycol-600 (PEG-600), a familiar non-toxic polymer used in pharmaceutical and other fields of industry. Methods: Reactions were carried out in alkaline medium and measured the kinetics by iodometry. One oxygen atom loss or two electrons transfer was observed per each molecule of periodate i.e., the rate of reaction was measured periodate converts to iodate because the formed iodate species is unable to oxidize the substrate molecules. Results: Based on log (a-x) versus t plots, order w. r. t. oxidant (periodate) is unity. Reactions were found to be independent of substrate (PEG-600) concentration. A decrease in rate with an increase in alkali concentration [OH–] was found and order was inverse fractional. Temperature dependence of reaction rate was studied and then calculated the corresponding Arrhenius parameters. Conclusion: An appropriate rate law was proposed by considering the above experimental results.

Ionic Liquid 4-(3-Methyl-1-imidazolio)-1-butanesulfonic Acid Hydrogen Sulfate-catalyzed Synthesis of Phthalazinetrione Derivatives

2012 ◽  
Vol 67 (7) ◽  
pp. 717-724
Author(s):  
Shihua Song ◽  
Xiang Deng ◽  
Zhi Guan ◽  
Yanhong He
Keyword(s):  
Ionic Liquid ◽  
Polyethylene Glycol ◽  
Condensation Reaction ◽  
Reaction Times ◽  
Solvent System ◽  
Environmentally Benign ◽  
Hydrogen Sulfate ◽  
One Pot ◽  
Simple Method ◽  
Peg 600

A simple method for the synthesis of phthalazinetrione derivatives by a one-pot three-component condensation reaction of phthalhydrazide, 1,3-dicarbonyl compounds and aldehydes catalyzed by the ionic liquid 4-(3-methyl-1-imidazolio)-1-butanesulfonic acid hydrogen sulfate ([BSO3HmIm]HSO4) is reported. Good to excellent yields were obtained in short reaction times in the solvent PEG 600 (polyethylene glycol 600) at 120 °C. The strategy proved to be efficient and environmentally benign. The catalyst/solvent system could easily be recovered and reused for at least 5 times without noticeable loss of activity

ChemInform Abstract: Metal-Free Synthesis of Methylene-Bridged Bis-1,3-dicarbonyl Compounds via Oxidative C-C Bond Cleavage of Tertiary Aliphatic Amines.

ChemInform ◽  
2015 ◽  
Vol 46 (5) ◽  
pp. no-no
Author(s):  
Li-Juan Xing ◽  
Xi-Mei Wang ◽  
Hong-Ying Li ◽  
Wen Zhou ◽  
Ning Kang ◽  
...  
Keyword(s):  
Bond Cleavage ◽  
Aliphatic Amines ◽  
Dicarbonyl Compounds ◽  
Metal Free

SYNTHÈSES D'ACIDES AMINOBUTYRIQUES. 1. ACIDES ALKYLAMINO-2 AMINO-4 BUTYRIQUES

1960 ◽  
Vol 38 (10) ◽  
pp. 1933-1938 ◽  
Author(s):  
Réal Laliberté ◽  
Louis Berlinguet
Keyword(s):  
Phthalic Acid ◽  
Starting Material ◽  
Aliphatic Amines ◽  
Alcoholic Medium ◽  
Excellent Yield

The syntheses of eight 2-alkylamino-4-aminobutyric acids are described. The starting material is 4-butyrolactone, which is opened with potassium phthalimide to give 4-phthalimidobutyric acid. After bromination the 2-bromo-4-phthalimidobutyric acid, obtained in excellent yield, is treated with aliphatic amines in alcoholic medium to give the desired substituted 2,4-diaminobutyric acids, which were characterized as the monohydrochlorides and the di(phenylcarbamates). Three of them cyclized easily to give the corresponding hydantoins. In the course of the reaction, substituted diamides of phthalic acid were isolated and characterized.

scholarly journals Characteristics, Performance of Blend CA/SPEEK Ultrafiltration Membranes Prepared by Phase Inversion Method using PEG 600 as an Additive

2017 ◽  
Vol 10 (1) ◽  
Author(s):  
G. Arthanareeswaran ◽  
N. Anatharaman ◽  
M. Raajenthiren
Keyword(s):  
Polyethylene Glycol ◽  
Water Content ◽  
Phase Inversion ◽  
Polymer Composition ◽  
Inversion Method ◽  
Hydraulic Permeability ◽  
Equilibrium Water Content ◽  
Ultrafiltration Membranes ◽  
Phase Inversion Method ◽  
Peg 600

Flat sheet asymmetric polymeric membranes is prepared by phase inversion method from homogeneous solution of 17.5 wt% cellulose acetate (CA) and sulfonated poly ether ether ketone (SPEEK) with polar solvent of N, N’– dimethylformamide (DMF). The different concentration of polyethylene glycol is used as the polymeric additives in the CA/SPEEK casting solution. The effects of polyethylene glycol 600 (PEG 600) concentration on the structure and performance of CA/SPEEK ultrafiltration membranes were investigated in more detail. The optimal preparation conditions were: 17.5 wt% total polymer composition, 65/35 wt% CA/SPEEK blend composition and 10 wt% PEG 600. The permeation performances of the membranes were evaluated in terms of pure water flux, equilibrium water content, hydraulic permeability, and solute rejection. The morphology and structure of the resulting membranes were observed by scanning electron microscope (SEM). CA/SPEEK membranes with higher concentration of 10 wt% PEG have higher PWF and equilibrium water content due to high porosity. With increase in PEG concentration from 0 to 10 wt%, the PWF increases from 129 to 259 lm–2h–1 in 65/35 wt% of CA/SPEEK as blend. When increasing concentration of PEG is substituted for SPEEK in proportion to form a homogeneous blend, the membrane hydraulic resistance reduces from 9.2 to 2.9 kPa/l.m–2.h–1for blend membranes with 0 to 10 wt % PEG 600 at 95/5 wt % CA/SPEEK composition. Solution of proteins of different molecular weight was used to study the permeation performance of prepared membranes using a batch membrane cell of 400 ml capacity.

Gold(III) N-Heterocyclic Carbene Complexes Mediated Synthesis of β-Enaminones From 1,3-Dicarbonyl Compounds and Aliphatic Amines

2011 ◽  
Vol 50 (5) ◽  
pp. 1840-1848 ◽  
Author(s):  
Manoja K. Samantaray ◽  
Chandrakanta Dash ◽  
Mobin M. Shaikh ◽  
Keliang Pang ◽  
Ray J. Butcher ◽  
...  
Keyword(s):  
Aliphatic Amines ◽  
Dicarbonyl Compounds ◽  
Carbene Complexes
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