Selective On-Resonance N.M.R. Irradiation of a Dipolar Double.

2000 ◽  
Vol 53 (4) ◽  
pp. 355 ◽  
Author(s):  
Frances Separovic ◽  
Nikolai R. Skrynnikov ◽  
Bryan C. Sanctuary
Keyword(s):  
Continuous Wave ◽  
Double Quantum ◽  
Relaxation Processes ◽  
Multiple Quantum ◽  
Detection Scheme ◽  
Experimental Scheme ◽  
Near Resonance ◽  
Quantum Transitions ◽  
Selective Irradiation ◽  
Efficient Transfer

Raman magnetic resonance where double-quantum transitions are observed without the need for multidimensional n.m.r. spectroscopy has been investigated further. Theoretical analysis of the on-resonance case where weak continuous-wave irradiation was applied at the frequency of a single-quantum transition was performed and guidelines for a consistent perturbation treatment were devised. Theoretical results agree well with experimental data obtained for a system of two dipolar coupled nuclei of spin oriented by a liquid crystal. The same approach is applicable to near-resonance experiments which are shown to be the optimal experimental scheme for Raman n.m.r. By using weak selective irradiation, a symmetric excitation–detection scheme can be realized for multiple-quantum n.m.r. experiments. Near- or on-resonance selective irradiation provides an efficient transfer of multiquantum coherence into observable coherences and could be used to study multiquantum relaxation processes.

Detection of Chemical Exchange in Methyl Groups of Macromolecules

2019 ◽  
Author(s):  
Michelle Gill ◽  
Andrew Hsu ◽  
Arthur G. Palmer, III
Keyword(s):  
Relaxation Rate ◽  
Chemical Exchange ◽  
Double Quantum ◽  
Methyl Groups ◽  
Multiple Quantum ◽  
Relaxation Data ◽  
E Coli ◽  
Methyl Trosy ◽  
Dynamics Simulations ◽  
Exchange Broadening

<div> <div> <div> <p>The zero- and double-quantum methyl TROSY Hahn-echo and the methyl <sup>1</sup>H-<sup>1</sup>H dipole- dipole cross-correlation nuclear magnetic resonance experiments enable estimation of multiple quantum chemical exchange broadening in methyl groups in proteins. The two relaxation rate constants are established to be linearly dependent using molecular dynamics simulations and empirical analysis of experimental data. This relationship allows chemical exchange broadening to be recognized as an increase in the Hahn-echo relaxation rate constant. The approach is illustrated by analyzing relaxation data collected at three temperatures for <i>E. coli </i>ribonuclease HI and by analyzing relaxation data collected for different cofactor and substrate complexes of <i>E. coli </i>AlkB. </p> </div> </div> </div>

Multiple quantum transitions

Physica ◽  
1961 ◽  
Vol 27 (7) ◽  
pp. 707-709 ◽  
Author(s):  
P. Jung
Keyword(s):  
Multiple Quantum ◽  
Quantum Transitions

NMR Multiple Quantum Transitions by Second Quantization Formalism

1970 ◽  
Vol 52 (8) ◽  
pp. 4041-4045 ◽  
Author(s):  
P. Bucci ◽  
P. Cavaliere ◽  
S. Santucci
Keyword(s):  
Multiple Quantum ◽  
Second Quantization ◽  
Quantum Transitions ◽  
Quantization Formalism
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