scholarly journals Detoxification as a Mechanism of Resistance I a Strain of the Cattle Tick Boophilus Micropluse (Canestrini) Resistant to Organophosphorus and Carbamate Compounds

1969 ◽  
Vol 22 (6) ◽  
pp. 1585 ◽  
Author(s):  
WJ Roulston ◽  
CA Schuntner ◽  
HJ Schnitzerling ◽  
JT Wilson

Strains of the cattle tick resistant to organophosphorus compounds were first found at Ridgelands in central Queensland in 1963 (Shaw and Malcolm 1964; Shaw 1966; Roulston, Stone, Wilson, and White 1968). Resistance of a different type was subsequently found at Biarra in south-eastern Queensland in 1966 (Roulston and Wharton 1967; Wharton 1967; Shaw, Cook, and Carson 1968). Ridgelands and Biarra strains of ticks both exhibit resistance to a wide range of organophosphorus and carbamate chemicals but differ in that resistance levels are higher and resistance extends to a wider range of chemicals in the Biarra strain. Biochemical investigations have shown that resistance in both strains is due to the presence of an acetylcholin-esterase system which is relatively insensitive to inhibition by organophosphorus chemicals (Lee and Batham 1966; Roulston, Schnitzerling, and Schuntner 1968; Schuntner, Roulston, and Schnitzerling 1968)

2016 ◽  
Vol 67 (2) ◽  
pp. 126-135 ◽  
Author(s):  
Syed M. Nurulain ◽  
Mohamed Shafiullah ◽  
Javed Yasin ◽  
Abdu Adem ◽  
Juma Al Kaabi ◽  
...  

AbstractOrganophosphorus compounds (OPCs) have a wide range of applications, from agriculture to warfare. Exposure to these brings forward a varied kind of health issues globally. Terbufos is one of the leading OPCs used worldwide. The present study investigates the cardiac effect of no observable dose of a metabolite of terbufos, terbufos-sulfone (TS), under non-diabetic and streptozotocin-induced diabetic condition. One hundred nanomoles per rat (1/20 of LD50) was administered intraperitoneally to adult male Wister rats daily for fifteen days. The left ventricle was collected for ultrastructural changes by transmission electron microscopy. The blood samples were collected for biochemical tests including RBC acetylcholinesterase, creatinine kinase (CK), lactate dehydrogenase (LDH), cholesterol, high density lipoprotein (HDL), low density lipoprotein (LDL), triglycerides, ALT, AST, and GGT. The study revealed about 10 % inhibition of RBC-AChE in two weeks of TS treatment in non-diabetic rats whereas RBC-AChE activity was significantly decreased in diabetic TS treated rats. CK, LDH, and triglycerides were significantly higher in diabetic TS treated rats. Electron microscopy of the heart showed derangement and lesions of the mitochondria of cardiomyocytes in the TS treated groups. The present study concludes that a non-lethal dose of TS causes cardiac lesions which exacerbate under diabetic condition. Biochemical tests confirmed the ultrastructural changes. It is concluded that a non-lethal dose of TS may be a risk factor for a cardiovascular disease, which may be fatal under diabetic condition.


CrystEngComm ◽  
2021 ◽  
Author(s):  
Ricardo D. Sosa ◽  
Jacinta C. Conrad ◽  
Michael Reynolds ◽  
Jeffrey D Rimer

Molecular modifiers can display a wide range of interactions with crystal interfaces to impede their growth. In this work we evaluate the efficacy of a naturally derived phosphorous-containing molecule, phytate,...


2019 ◽  
Vol 13 (1) ◽  
pp. 57-67
Author(s):  
Monica Dumitrașcu ◽  
Mihaela Lungu ◽  
Sorin Liviu Ștefănescu ◽  
Victoria Mocanu ◽  
Gabi Mirela Matei ◽  
...  

Abstract As low-input environmentally friendly agricultural practices are currently associated with the delivery of a wide range of public goods and socioeconomic benefits, the strategy of European Union in mitigating climate change effects, protecting environment and ensuring public health has, among others, focused around preserving the High Natural Value (HNV) areas. About a quarter of the land in Romania is potentially covered by HNV farming and eligible for associated support payments, mostly along the chain of the Carpathian Mountains. Since soil systematic data on HNV area are scarce, recent research developments currently undertake to build up a first national HNV soil data base. Soil fertility state in a HNV payment eligible area of south-eastern Transylvania was studied in seven in-depth dug profiles and seven additional shallow dug profiles. Soil samples were taken by genetic horizons as well as agrochemical samples from the upper soil layers (0-20 cm). Physical, chemical, and microbiological analyses revealed that the studied soils have a medium clayey loamy texture, good fertility and are subject to an adequate HNV management in the area, as the analytical values mostly range in favorable intervals for plant growth and nutrition. Thus, soil reaction is moderately acid up to slightly alkaline in the presence of carbonates, the soil organic matter, generally well mineralized, reaches fair levels and the high and very high cation exchange capacity ensure good conditions for plants growth and nutrition whilst nitrogen and potassium supply is adequate. Phosphorus is the only element in short supply – a situation often encountered in Romania unfertilized soils. Soil bulk density and total porosity are also favorable for root growth and spreading and plant nutrition. Microorganisms’ activity is diverse and is also adequate for plant nutrition.


1973 ◽  
Vol 21 (1) ◽  
pp. 113 ◽  
Author(s):  
VJ Hill ◽  
RH Groves

Three variants or forms of Chondrilla juncea L. (skeleton weed) are distinguished in south-eastern Australia. The forms (designated A, B, and C) differ in inflorescence morphology and fruit characters, but mainly in the shape of rosette leaves, for which quantitative expressions of the differences have been developed. There were no significant differences within each form in rosette leaf shape when grown in a wide range of environments. First and second progenies of the three forms, presumably apomictic, retained the identity of their parents, as did leaves of rosettes arising vegetatively from the root system after removal of the parental rosette. The geographical limits of distribution of the forms are given, based on results from field observations and from plants grown in a glasshouse either from seed or clonal material. Plants of form A are widespread and occur in south-eastern Australia over a wide range of latitude, climate, and soil type. With one exception, the distribution of plants of forms B and C in 1969 was restricted to central New South Wales, where the forms are distributed sympatrically with plants of form A. Form B plants are confined at present to an area bounded approximately by Young, Orange, Peak Hill, and Marsden, though these boundaries are extending. Leaf emergence rates, times to stem elongation, and times to flowering are presented for the three forms. Differences between forms in these characters under some conditions are shown to exist, as well as differences between forms in their ability to regenerate vegetatively. Form C plants, at present more restricted geographically, seem to have a greater potential for regeneration from rootstocks than form A plants, already widespread throughout south-eastern Australia. The variation described in this paper is discussed in relation to control of other weed species, especially apomicts.


1988 ◽  
Vol 28 (3) ◽  
pp. 377 ◽  
Author(s):  
GJ Leach ◽  
DF Beech

Interception of radiation by chickpea (Cicer arietinum L.), in a year of below-average rainfall, and water use in both wet and dry years, were studied on a deep vertisol soil at Dalby, south-eastern Queensland. Measurements were made on 4 accessions (cv. Tyson, K223, CPI 56287 and CPI 56289) grown at a number of row spacings. Canopies intercepted less than 20% of incident radiation during the first 70 days after sowing (DAS) in the dry year (1980) before radiation interception reached a peak in mid-September (100 DAS) at about 70% interception in 250 mm rows. Above-ground dry matter was linearly related to intercepted radiation to the end of September (119 DAS), giving an efficiency of radiation conversion of 1.4 g DM per MJ of intercepted photosynthetically active radiation. Efficiency of conversion was marginally higher with 125 mm than with 62.5 mm intra-row spacing in rows 250 mm apart. In a wet year (1979), chickpea extracted water from below 1 m depth in the soil profile and used 356 mm water. In the dry year, only 16 1 mm water was used and none was extracted from below 1 m. K223 used water faster than cv. Tyson, and extraction was faster with close than with wide row spacing. Above-ground dry matter was produced at an efficiency of 3.4 (1980) to 4.2 (1979) g m-2 mm-I of water during the main period of growth through September, and a mean of 0.7 g m-2 seed for 2 seasons was produced per mm of water used over the whole season. The small differences in water extraction between accessions and spacing treatments were reflected during pod-filling as differences in plant water potential of 0.1-0.2 MPa during the early afternoon stress period. Chickpea appears to have poor stomata1 control over water loss, being comparable to summer legumes like soybean rather than to cowpea. We conclude that the benefit of close row spacing in enhancing radiation interception outweighs the small disadvantage from accelerated water depletion. The ability of chickpea to produce useful seed yields over a wide range of soil water availability makes it well suited for opportunistic winter cropping.


2017 ◽  
Vol 68 (12) ◽  
pp. 2366 ◽  
Author(s):  
Paul I. Boon

The distribution and productivity of mangroves is directly affected by a wide range of climatic drivers, including temperature, frost, rainfall, evaporation and storm activity, which, in turn, influence a suite of secondary drivers, including changes in freshwater run-off and sediment supply, groundwater dynamics and inter-species competitiveness. The highest-latitude expression of mangroves globally is at Millers Landing, Victoria (38°45′S), and because the vigour and productivity of mangroves across much of Victoria is thought to be limited by low winter temperatures and the incidence and severity of frosts, it is likely that mangroves will be among the first plant communities to be affected by climate change in coastal south-eastern Australia. An increase in plant vigour is likely, but there are almost no historical data with which to compare current rates of primary production. An extension of mangroves to higher latitudes on the mainland is impossible because of the geomorphology of the land that lies further to the south. Small-scale changes in distribution, including the progressive encroachment of mangroves into coastal saltmarsh, are likely to be among the clearest indications of the response of mangroves to a warming climate. Increased effort into tracking changes in mangrove vigour, productivity and distribution is clearly warranted.


PRILOZI ◽  
2015 ◽  
Vol 36 (3) ◽  
pp. 154-159
Author(s):  
Zoran Gucev ◽  
Velibor Tasic ◽  
Momir Polenakovic

Abstract The 4th meeting on rare diseases in South Eastern Europe (SEE) was held in Skopje, at the Macedonian Academy of Sciences and Arts (MASA) on the 14th of November 2015. The focuses were metabolic, rare brain diseases as well as the rare dysmorphic syndrome. The authors of the report are particularly keen on stating that one of the main goals of the meeting, namely to help the treatment of patients with rare disease has begun to bear fruits. The talk on an iminosugar-based pharmacological chaperone compound as a drug candidate for the treatment of GM1-gangliosidosis and mucopolysaccharidosis IVB (Morquio disease type B) was enlightening. To date, there is no treatment available to be offered to patients, but chaperones lead mutated proteins to adopt a native-like conformation and to successfully traffic to their normal cellular destination. DORPHAN is developing an iminosugar-based pharmacological chaperone compound for the treatment of GM1-gangliosidosis and mucopolysaccharidosis IVB. A talk on recent developments in the laboratory diagnosis of mucopolysaccharidoses (MPS) was particularly interesting, covering the laboratory diagnosis of the MPS diseases by a strategy of clinical examination, biochemical analysis of urine samples, enzyme tests and genetic characterization of underlying mutations. New techniques were developed, including analysis of urinary glycosaminoglycans with tandem mass spectrometry, miniaturized enzyme tests or novel synthetic substrates for enzyme assays using mass spectrometry detection of products using dried blood spots. Feasibility and cost-effectiveness of these methods in newborn screening programs have been demonstrated. Neuromuscular RDs, and especially familial amyloid polyneuropathy (FAP) were a topic of the Bulgarian colleagues. Diagnosis, screening and the role of microglia were also topics of particular interest. In summary, this year RD meeting was exciting and productive on a wide range of diseases and on a novel insights on diagnosis and treatment. New methods are expanding our capabilities for a fast and precise diagnosis. Novel knowledge offers better distinction on whom to treat with which medications (e.g. steroid dependent nephrotic syndrome). Novel diseases or variants are published (segmental overgrowth). The authors of the report are particularly keen on stating that one of the main goals of the meeting, namely to help the treatment of patients with rare disease has begun to bear fruits. Namely, the Health Fund of Macedonia for the first time treats the patients with Gaucher′s disease. We are hopeful that the number of patients treated for Gaucher′s disease and the number of treated patients with other treatable RDs diseases will continue to grow.


Author(s):  
D. Abate ◽  
A. Avgousti ◽  
M. Faka ◽  
S. Hermon ◽  
N. Bakirtzis ◽  
...  

The World Heritage Convention, drawn by various international bodies in 1972, was designed to protect cultural or natural places of outstanding universal value so that future generations may be able to enjoy them. Responding to these principles as well as to the Charter on the Preservation of Digital heritage (Vancouver, 2003), this multidisciplinary project, which involves archaeologists, art historians, conservators and computer scientists, aims to create an open access, 3D interactive online geo-database of endangered architectural and archaeological heritage in the South Eastern Mediterranean basin; a region of tremendous cultural importance whose rech heritage is unfortunately threatened by both natural and human factors. A wide range of 3D modelling and topographic techniques have been applied to create accurate reconstructions of heritage sites, enriched by a extensive array of metadata.


EDIS ◽  
2020 ◽  
Vol 2020 (2) ◽  
Author(s):  
Yuexun Tian ◽  
Phillip E Kaufman

The Asian longhorned tick, Haemaphysalis longicornis Neumann, also known as the longhorned tick, bush tick (Australia), and cattle tick (New Zealand), is a three-host tick native to East Asia. This tick has been categorized as an invasive species in Australia, New Zealand, and several Pacific Islands. In the U.S., an Asian longhorned tick infestation was recorded in New Jersey during the fall of 2017. This tick is somewhat unique in that females are capable of parthenogenesis, meaning that females can produce offspring without having mated with males. The Asian longhorned tick feeds on a wide range of hosts including birds and mammals, including humans. This tick is considered a medical and veterinary vector due to its ability to transmit pathogens that cause disease in humans and other animals.https://edis.ifas.ufl.edu/in1263


1988 ◽  
Vol 36 (3) ◽  
pp. 355 ◽  
Author(s):  
KM Old ◽  
MJ Dudzinski ◽  
JC Bell

Isozyme characteristics of 280 isolates from populations of Phytophthora cinnamomi in native veg- etation in six locations in south-eastern Australia were examined at 19 enzyme loci. No new enzyme genotypic arrays were identified as compared with earlier samplings. This work indicates that the low variability for P. cinnamomi in Australia obtained in earlier work, from separate isolates in a wide range of locations, is paralleled in detailed population samples in south-eastern Australia. At one location, A1 and A2 mating types coexisted in soil samples. The lack of recombinants in these population samples suggests an absence of sexual reproduction in the field.


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