scholarly journals The Pre-Natal Development of Skin and hair in Cattle (Bos Taurus L.)

1959 ◽  
Vol 12 (1) ◽  
pp. 72 ◽  
Author(s):  
AG Lyne ◽  
Margaret J Heideman

A histological study has been made of the development of the skin and hair follicles in 33 foetuses, ranging in age from 68 to 274 days, and seven new-born specimens, of various breeds of Bos taurus L. Skin samples were taken from the mid-lateral region of the trunk, and both serial sections and whole mount preparations have been examined. Extensive use has been made of' counts of the follicle and hair population as well as skin and hair follicle measurements which hitherto have apparently received little attention in studies of this type.

2014 ◽  
Vol 2014 ◽  
pp. 1-6
Author(s):  
Alexandra Rippa ◽  
Olga Leonova ◽  
Vladimir Popenko ◽  
Andrey Vasiliev ◽  
Vasily Terskikh ◽  
...  

In adult skin, hair follicles cyclically self-renew in a manner that recapitulates embryonic hair follicle morphogenesis. The most common pathology of hair in adults is alopecia, which is hair loss to different extent. There are a number of murine models of alopecia including spontaneous mutations. In the present study, we worked with double homozygouswe/we wal/walmice which demonstrate symptoms closely resembling human alopecia. Using whole-mount preparations of epidermis of E18.5 embryos we show that hair follicle defects can be revealed as early as during embryonic morphogenesis in these mutants. The number of hair follicles was reduced almost 1.5-fold in mutant skin. The shape of the early stage small follicles was altered in mutant animals as compared to control ones. Additionally, follicles of mutant embryos were wider at the point of conjunction with interfollicular epidermis. We believe that the mutant mice studied represent a fascinating model to address the problem of hair loss. We demonstrated alterations in the morphogenesis of embryonic hair follicle inwe/we wal/waldouble homozygous mice developing alopecia postnatally. We suppose that incorrect morphogenesis of hair follicles during embryogenesis is closely related to alopecia in the adult life. Unveiling the mechanisms involved in altered embryogenesis may elucidate the pathogenesis of alopecia.


1954 ◽  
Vol 5 (4) ◽  
pp. 745 ◽  
Author(s):  
HB Carter ◽  
DF Dowling

Skin biopsy specimens were collected at a standard midside position from 321 individual cattle (Bos taurus L.) of known age or in defined age groups on pastoral properties in New South Wales and Queensland. Beef cattle were represented by samples from the breeds: Aberdeen Angus, Devon, Hereford, and Shorthorn. Dairy cattle were represented by samples from the breeds: Australian Illawarra Shorthorn, Holstein-Friesian, Jersey, and Red Poll. Data were also obtained on 30 beef Shorthorns repeatedly sampled from birth to the age of 2-1/2 years under severe drought conditions in north Queensland. In all specimens each hair follicle was associated with an apocrine gland as well as a sebaceous gland and an arrector pili muscle. Thus, all hair follicles were homologous with the primary follicles of sheep; no secondary follicles were at any time observed; hence, there was no follicle group comparable in its complexity to that in the sheep and many other mammalian species. Further and more systematic observations by the biopsy and histological methods used in this work are necessary to examine the true nature of breed differences in the follicle and apocrine gland population density of the skin. The Jersey appears to have a denser coat. The data presented in this paper emphasize the dual importance of age and nutritional status of the animal on the hair follicle population density.


1955 ◽  
Vol 6 (4) ◽  
pp. 645 ◽  
Author(s):  
DF Dowling

Skin samples taken with a trephine of known size from Shorthorn (Bos taurus L.) and Zebu (B. indicus L.) cattle were used to determine the density of hair follicles and apocrine glands in the skin. The repeatability of the measurement of density on the same animal was found to lie between 78 and 90 per cent. The expansion of the skin as the animal grows, and the manner in which the plane of nutrition can modify growth and so the extent of expansion, has a predominating effect on the hair follicle and apocrine gland density. There is a significant difference between ages, but for each breed the regression coefficients of log follicle number on log heart girth within age groups are not significantly different. The mean number of hair follicles per sq. cm in Zebus was 1698, in Zebu crosses 1321, and in Shorthorns on a low plane of nutrition 1064. In Shorthorns on a high plane the number was 764. All differences were statistically significant.


1960 ◽  
Vol 13 (4) ◽  
pp. 584 ◽  
Author(s):  
AG Lyne ◽  
Margaret J Heideman

A histological study has been made of the development of the skin and hair follicles in 22 crossbred (Brahman X Hereford or Brahman X Shorthorn) cattle foetuses, ranging in age from 77 to 263 days, and in three new�born calves.


1957 ◽  
Vol 10 (2) ◽  
pp. 197 ◽  
Author(s):  
AG Lyne

A histological study has been made of the development and replacement of pelage hairs in the bandicoot, Perameles nasuta Geoffroy. Skin samples were taken from the mid-lateral region of the trunks of 18 specimens from eight different litters at estimated ages ranging from birth to 526 days. Six specimens were sampled more than once.


1988 ◽  
Vol 50 (2) ◽  
pp. 271-276 ◽  
Author(s):  
Ryuichiro KUWANA ◽  
Seiji ARASE ◽  
Yasushi SADAMOTO ◽  
Hideki NAKANISHI ◽  
Katsuyuki TAKEDA

2020 ◽  
Vol 26 (27) ◽  
pp. 3251-3268
Author(s):  
Shweta Ramkar ◽  
Abhishek K. Sah ◽  
Nagendra Bhuwane ◽  
Ishwari Choudhary ◽  
Narayan Hemnani ◽  
...  

The pilosebaceous unit is the triad comprising of hair follicle, arrector pilli muscle, and sebaceous gland. Drug delivery to and through the hair follicles has garnered much attention of the researchers and the hair follicles represent an attractive target site via topical applications. They are bordered by capillaries and antigenpresenting cells, connected to the sebaceous glands and the bulge region of the hair follicle anchors the stem cells. The nano lipid carriers have the propensity to penetrate through the skin via transcellular route, intracellular route and follicular route. It has been established that nano lipid carriers have the potential for follicular drug delivery and provide some advantages over conventional pathways, including improved bioavailability, enhanced penetration depth, fast transport into the skin, tissue targeting and form a drug reservoir for prolonged release. This review describes the pilosebaceous unit (PSU) and related diseases and the recent lipid-based nanotechnology approaches for drug delivery to the follicular unit as well as related issues. Different types of nano lipid carriers, including ethosomes, liposomes, nanoparticles, solid lipid nanoparticles (SLNs), and nano lipid carriers (NLCs) have been reported for follicular drug delivery. Targeted drug delivery with nano-lipid carriers has the potential to augment the efficacy of drugs/bioactives to treat diseases of PSU. This review systematically introduces the activities of different formulations and the use of nano lipid carriers in treating PSU related disorders like alopecia, acne, and hirsutism.


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