The metabolism of phosphorus and calcium in sheep during intravenous infusion of phosphorus

1982 ◽  
Vol 33 (5) ◽  
pp. 827 ◽  
Author(s):  
KM Schneider ◽  
RC Boston ◽  
DD Leaver
Keyword(s):  
Soft Tissue ◽  
Control Period ◽  
Compartmental Analysis ◽  
Phosphorus Concentration ◽  
Hormonal Changes ◽  
Deconvolution Analysis ◽  
Tracer Techniques ◽  
Calcium And Phosphorus ◽  
The Difference ◽  
Tissue Accretion

The metabolism of calcium and phosphorus in mature sheep, given firstly a chaff diet and then chaff with an intravenous supplement of 1.5-2.0 g/day of phosphorus, was studied by using tracer techniques and compartmental analysis. Absorption was also studied by deconvolution analysis and a technique relating the excretion of tracer in faeces to that of an insoluble marker. Under the conditions of the experiment most of the additional phosphorus infused intravenously was excreted in the faeces, and this was due to a concurrent increase in the endogenous secretion and a decrease in the efficiency of absorption of phosphorus. In sheep given 2.0 g of phosphorus per day, the phosphorus concentration in plasma increased 2.5-4 times, but the excretion of phosphorus in the urine remained small (less than 0.3 g/day) compared with the excretion of 2.5 g/day of phosphorus in the faeces. One feature of the experiment was the difference in the behaviour of bone and soft tissue reservoirs between the sheep given 1.5 g/day of phosphorus and those given 2.0 g/day. In the former group accretion and resorption of calcium and phosphorus in bone and soft tissue increased when compared with the control period, whereas in the latter group bone and soft tissue accretion of phosphorus was unchanged and resorption increased slightly. These results are discussed in terms of the hormonal changes that occur following changes in plasma calcium and phosphorus.

Biokinetics of Bone Tracers by Means of Deconvolution Analysis - Comparison of 99mTc MDP, 99mTc DPD and 99mTc EHDP

1982 ◽  
Vol 21 (04) ◽  
pp. 145-149
Author(s):  
P. Stritzke ◽  
E. Kröger ◽  
C. Schneider ◽  
G. Wasmus ◽  
J. Knop
Keyword(s):  
Soft Tissue ◽  
Time Course ◽  
Soft Tissues ◽  
Transfer Functions ◽  
Plasma Concentrations ◽  
Deconvolution Analysis ◽  
Transfer Rates ◽  
Extravascular Fluid ◽  
Late Transfer ◽  
The Difference

Transfer functions of 99mTc methylene diphosphonate (MDP), 99mTc 2,3-dicarboxypropane-l,l-diphosphonate (DPD) and 99mTc ethane-l-hydroxy-l,l-diphosphonate (EHDP) into bone and extravascular fluid of soft tissues were determined in 5 dogs by deconvolution analysis of the time-course of plasma, soft tissue and bone radioactivity. The transfer rates 5 min after injection - indicating the rapid exchange of the tracer between plasma and the extravascular fluid -decrease in the order MDP > EHDP > DPD (P < 0.05). The transfer rates into bone - determined from transfer rates between 30 and 60 min - decreased in a different order, i.e. MDP > DPD > EHDP (P<0.05). The fractional bone uptake of diphosphonates estimated from the ratio of early to late transfer rates was slightly greater for DPD than for MDP and EHDP respectively. The difference between DPD and MDP was not significant (P > 0.05). The average bone and soft tissue concentrations of DPD 60 min after injection were greater than that of MDP and EHDP due to different plasma concentrations (DPD > EHDP > MDP), whereas the bone-to-soft tissue ratios decreased in the sequence MDP > DPD > EHDP (P < 0.05). - Our results reveal different biokinetics of MDP, DPD and EHDP explaining variations in osseous and soft tissue uptake suggesting that deconvolution analysis could play an important role in bone scan interpretation.

Comparative analysis of changes of bioelectrical activity of the brain during the neutral touch and during the performance of the myofascial release technique

2018 ◽  
pp. 46-55
Author(s):  
A. F. Belyaev ◽  
G. E. Piskunova
Keyword(s):  
Soft Tissue ◽  
Brain Activity ◽  
Direct Action ◽  
Brain Regions ◽  
Therapeutic Touch ◽  
Bioelectrical Activity ◽  
Therapeutic Action ◽  
Osteopathic Treatment ◽  
The Difference ◽  
Multiparameter Analysis

Introduction. One of the main tools of an osteopath are soft tissue techniques, which have a number of particular qualities such as minimization of force and duration of indirect techniques with an emphasis on muscle and ligamentous structures; combination of gestures, tendency to maximal relaxation and exclusion of direct action on pathological symptoms such as tension, overtone and pain. Minimization of the force applied during the performance of soft tissue techniques often invites a question whether there are differences between the usual touch and the therapeutic touch of an osteopath.Goal of research - to reveal the changes in the bioelectrical activity of the cerebral cortex arising in the process of osteopathic treatment in order to prove its specifi city in comparison with nonspecifi c tactile stimulation (neutral touch).Materials and methods. 75 people were examined with the use of multiparameter analysis of multichannel EEG in different times. 25 patients were clinically healthy adults, whereas 50 patients had signs of somatic dysfunctions.Results. Computer encephalography permits to perceive the difference between the neutral touch and the therapeutic action. An identifi cation reaction is a response to the neutral touch (changes in brain bioelectrical activity with an increase in statistically signifi cant connections in the temporal lobes), whereas the therapeutic action provokes the state of purposeful brain activity during still point (intensifi cation of frontooccipital interactions).Conclusions. Osteopathic action causes additional tension in the processing of incoming information, which requires participation of different brain regions, including interhemispheric mechanisms associated with analysis, maintenance of attention and regulation of targeted activities.

Quality characteristics and hatchability of eggs and serum electrolytes concentration of Gola, Giribaz and Ghiachundi pigeon breed

2021 ◽  
Vol 7 (2) ◽  
pp. 107-112
Author(s):  
Khaled Mahmud Sujan ◽  
Manik Biswas ◽  
Sakhawat Hossain Tareq ◽  
Md Kamrul Islam
Keyword(s):  
Body Weight ◽  
Serum Sodium ◽  
Analytical Techniques ◽  
The Body ◽  
Phosphorus Concentration ◽  
Serum Electrolytes ◽  
Final Body Weight ◽  
Sodium Potassium ◽  
Crop Fields ◽  
Calcium And Phosphorus

The weather and vast areas of crop fields along with housing premises of Bangladesh are suitable for pigeon farming. The experiment was conducted to evaluate the characteristics of eggs and serum electrolyte concentration of Gola, Giribaz and Ghiachundi pigeon squabs. Three pairs of each breed were reared in the cage with commercial feed and water. After laying eggs, the length and width of eggs were recorded. After hatching of eggs, eggshell thickness was recorded. The thickness of the eggshell was 0.15±0.01 mm, 0.15±0.01 mm, 0.15±0.00 mm for Gola, Giribaz and Ghiachundi breeds respectively. The body weights of the squabs were recorded at 7th and 45th day. The squabs were sacrificed on 45th day and the blood sample was collected and serum sodium, potassium, calcium and phosphorus concentration were measured by using appropriate analytical techniques. Serum sodium, potassium, calcium and phosphorus were: 102.93±15.95 (mmol/L), 11.18±2.19 (mmol/L), 6.20±1.11 (mmol/L), 4.53±0.45 (mmol/L) for Gola breed; 101.48±2.12 (mmol/L), 12.15±0.96 (mmol/L), 5.65±1.09 (mmol/L), 4.53±0.36 (mmol/L) for Giribaz breed and 95.18±6.71 (mmol/L), 11.99±0.91 (mmol/L), 5.09±0.75(mmol/L), 4.81±0.24 (mmol/L) for Ghiachundi breed respectively. A positive correlation has been found between thickness of eggshell and phosphorus while there is a negative correlation with calcium for Gola breed; both have been found insignificant for Giribaz breed and only calcium has been found significant for Ghiachundi breed. A strong correlation between the final body weight of the squab and K for the Gola breed; between the final body weight of the squab and Ca, P, K for Giribaz breed and between the final body weight of the squab and Ca, Na, K have been found. It could be concluded that serum electrolytes having an influential effect on egg characteristics and body weight of corresponding pigeon breed. Asian J. Med. Biol. Res. 2021, 7 (2), 107-112

Hormonal changes and enforced diving in the harbor seal Phoca vitulina. II. Plasma catecholamines

1982 ◽  
Vol 242 (5) ◽  
pp. R528-R532 ◽  
Author(s):  
A. J. Hance ◽  
E. D. Robin ◽  
J. B. Halter ◽  
N. Lewiston ◽  
D. A. Robin ◽  
...  
Keyword(s):  
Recovery Period ◽  
Control Period ◽  
Plasma Catecholamines ◽  
Harbor Seal ◽  
Phoca Vitulina ◽  
Harbor Seals ◽  
Hormonal Changes ◽  
Inotropic Effects ◽  
Arterial Constriction

Plasma epinephrine and norepinephrine concentrations were measured in five harbor seals, Phoca vitulina, during a control period, during a 6-min dive, and during a 30-min postdiving recovery period. Measurements were performed with and without prior glucose administration. Control epinephrine concentrations [189 +/- 118 (SD) pg/ml] and norepinephrine concentrations (340 +/- 191 pg/ml) were similar to resting values in humans. During diving there are dramatic increases in both epinephrine and norepinephrine concentrations, which returned to control values by 30 min of the postdiving recovery period. A similar pattern was found after glucose infusion. The increased catecholamines were not the primary mechanism responsible for arterial constriction during the dive. Persistent diving bradycardia suggests obliteration of the chronotropic effects of catecholamines during the dive. An unchanged stroke volume suggests obliteration of the inotropic effects of catecholamines during the dive. Catecholamines do not appear to be involved in postdiving hyperglycemia and hyperglucogenemia. Neither the regulatory role of increased catecholamines nor the physiological function of increased catecholamines was apparent from the studies. However, dramatic increases in plasma catecholamines during diving appear to be an important component of the hormonal response to prolonged diving in aquatic mammals.

A randomized trial for the treatment of high-grade soft-tissue sarcomas of the extremities: preliminary observations.

1986 ◽  
Vol 4 (4) ◽  
pp. 552-558 ◽  
Author(s):  
F Gherlinzoni ◽  
G Bacci ◽  
P Picci ◽  
R Capanna ◽  
P Calderoni ◽  
...  
Keyword(s):  
Adjuvant Chemotherapy ◽  
Soft Tissue ◽  
Local Treatment ◽  
Soft Tissue Sarcomas ◽  
Rank Test ◽  
High Grade ◽  
Chemotherapy Group ◽  
The Difference ◽  
To Receive ◽  
Observation Period

A new trial for evaluating the effectiveness of adjuvant chemotherapy in high-grade soft-tissue sarcomas of the extremities in adult patients is presented. All patients after local treatment were randomized into two arms, one without further therapy and the other to receive adjuvant chemotherapy (Adriamycin [Farmitalia-Carlo Erba, Milan, Italy], 450 mg/m2). The preliminary results of the study are reported at a median observation period of 27.6 months. Of the 59 patients who entered the study, 79.1% in the chemotherapy group are without sign of disease, whereas the corresponding figure in the nonadjuvant chemotherapy group is 54.3%. The difference between the two groups is statistically significant (P less than .005, log rank test). These preliminary observations encourage continuation of the study.

Effect of Ischemia on the Length-Tension Diagram of Mammalian Skeletal Muscle

1956 ◽  
Vol 188 (1) ◽  
pp. 113-117 ◽  
Author(s):  
L. C. Senay ◽  
B. A. Schottelius
Keyword(s):  
Skeletal Muscle ◽  
Soft Tissue ◽  
Mammalian Skeletal Muscle ◽  
Passive Tension ◽  
Active Tension ◽  
Rapid Loss ◽  
The Difference ◽  
And Control ◽  
Contralateral Muscle

Ischemia was produced in the gastrocnemii of 13 rats by ligation and section of all soft tissue between knee and thigh. The contralateral muscle in each case served as a control. Isometric length-tension diagrams were obtained for both control and experimental muscles from 4 mm below resting length to 9 mm beyond resting length, stretch being imposed in 1-mm increments. In comparing the experimental and control length-tension diagrams, a 15% loss in active tension at resting length was observed in both the experimental and control muscles when the tension developed during an initial isometric tetanus was compared with tension developed at this length during the course of the length-tension diagram. The cause of this decrease is not certain but fatigue and changes in muscle extensibility were thought to play prominent roles. The active tension developed by the ischemic muscles was found to be less at all degrees of stretch, and in most instances this difference was significant. This tension loss in the ischemic muscles was not constant; plotting the difference between control and ischemic active tension revealed that from –4 mm to +2 mm of stretch the difference increased, while from +2 to +9 mm of stretch the tension loss decreased. This latter finding was further investigated by determining fatigue rates at selected degrees of stretch in ischemic and control muscles of 40 rats. These studies indicated that the ischemic muscles suffered a more rapid loss of active tension developed at degrees of stretch less than +2 mm but the control muscles had a more rapid active tension loss at lengths greater than +2 mm of stretch. An explanation for this is suggested. Development of contracture was thought to be the cause of the increase in the passive tension exhibited by the ischemic muscles.

Effect of 1 α-hydroxycholecalciferol on calcium and phosphorus concentration in goat milk

1996 ◽  
Vol 21 (1) ◽  
pp. 45-49
Author(s):  
M.Ben Goumi ◽  
M.-J. Davicco ◽  
V. Coxam ◽  
F. De La Farge ◽  
J.-P. Barlet
Keyword(s):  
Goat Milk ◽  
Phosphorus Concentration ◽  
Calcium And Phosphorus

The influence of dietary calcium and phosphorus concentration on their absorption in the cow

1967 ◽  
Vol 68 (2) ◽  
pp. 263-268 ◽  
Author(s):  
R. Manston
Keyword(s):  
Dietary Intake ◽  
Dietary Calcium ◽  
Phosphorus Concentration ◽  
Isotope Techniques ◽  
Phosphorus Absorption ◽  
Calcium And Phosphorus

Experiments were carried out in dry, nonpregnant cows by varying dietary concentrations of calcium and phosphorus. Calcium and phosphorus absorption were measured by balance and isotope techniques. It was found that absorption of calcium or phosphorus increased when the dietary intake of the element increased, but only for a few days.

scholarly journals Serum calcium and phosphorus concentration and alkaline phosphatase activity in healthy children during growth and development

2008 ◽  
Vol 61 (7-8) ◽  
pp. 393-399 ◽  
Author(s):  
Ljiljana Savic ◽  
Dejan Savic
Keyword(s):  
Alkaline Phosphatase ◽  
Phosphatase Activity ◽  
Serum Calcium ◽  
Alkaline Phosphatase Activity ◽  
Growth And Development ◽  
Age Groups ◽  
Growth Spurt ◽  
Phosphorus Concentration ◽  
Healthy Children ◽  
Calcium And Phosphorus

Introduction. Many changes happen during growth and development in an organism as a result of important hormone changes, especially biohumoral ones. These changes make a problem when interpreting biochemical results in pediatric population. The most important changes are intensive calcium and phosphorus metabolic turnover in bone tissue with changes in alkaline phosphatase activity as a result of osteoblast activity. The aim of this study was to follow the serum calcium and phosphorus concentration and alkaline phosphatase activity in children 1-15 years old in different growth and development period and of different sexes and to fortify the influence of growth and development dynamics on biohumoral status in healthy male and female children. Material and methods. We evaluated 117 healthy children of both sexes from 1-15 years of age and divided them into three age groups: 1-5, 6-10 and 11-15 years. We followed the serum calcium and phosphorus concentration and alkaline phosphatase activity in different groups and in different sexes. Results and conclusion. Our investigation found significantly higher values of serum calcium in boys than in girls with no important changes between the age groups and significantly higher values of serum phosphorus in the youngest age group in all children and in different sexes with no important sex differences. Alkaline phosphatase activity followed the growth spurt and was the biggest in 6-10 years group in girls and in 11-15 years group in boys.

scholarly journals Reproducibility and reliability of three-dimensional soft tissue landmark identification using three-dimensional stereophotogrammetry

2016 ◽  
Vol 86 (6) ◽  
pp. 1004-1009 ◽  
Author(s):  
Asli Baysal ◽  
Ahmet Oguz Sahan ◽  
Mehmet Ali Ozturk ◽  
Tancan Uysal
Keyword(s):  
Soft Tissue ◽  
Statistical Significance ◽  
Intraclass Correlation ◽  
Three Dimensional ◽  
Correlation Coefficients ◽  
Intraclass Correlation Coefficients ◽  
Paired Samples ◽  
Landmark Identification ◽  
The Difference ◽  
Intraexaminer Reliability

ABSTRACT Objective: To evaluate the intraexaminer repeatability and interexaminer reproducibility of soft tissue landmarks on three-dimensional (3-D) stereophogrammetric images. Materials and Methods: Thirty-four stereophotogrammetric images were taken and 19 soft tissue points were identified. The images were obtained using the 3-DMD Face (3-DMD TM Ltd, Atlanta, Ga) system. Two examiners marked 34 images manually with a mouse-driven cursor 4 weeks apart. Intraexaminer marking differences were calculated and classified as &lt;0.5 mm, 0.5–1 mm, and &gt;1 mm. Intraclass correlation coefficients were calculated for intraexaminer reliability. A paired-samples t-test was used to evaluate the difference between the examiners. Interexaminer reproducibility was evaluated by kappa analysis. Statistical significance was set at P &lt; .05. Results: Only one landmark (labiale superior) had an intraexaminer marking difference less than 0.5 mm. Existing landmarks had an intraexaminer difference less than 1 mm, but higher than 0.5 mm. The intraclass correlation coefficients (ICCs) indicated good intraexaminer repeatability for both observers. The ICC range for examiners 1 and 2 was 0.986–1.000 and 0.990–1.000, respectively. Kappa scores showed good interexaminer agreement, especially on the z-axis. Conclusions: Except labiale superior, the soft tissue landmarks used in this study were shown to have moderate reproducibility, but the difference between the landmarks was less than 1 mm, and they had clinically acceptable reproducibility.

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