Some functional manifestations of the protein depletion of sheep tissues

1962 ◽  
Vol 13 (6) ◽  
pp. 1082 ◽  
Author(s):  
CJ Masters ◽  
DJ Horgan
Keyword(s):  
Functional Ability ◽  
Serum Levels ◽  
Low Energy ◽  
Urinary Volume ◽  
Experimental Diet ◽  
Total Proteins ◽  
Merino Sheep ◽  
Low Protein ◽  
Sequential Measurement ◽  
Low Energy Diet

In order to elucidate the alterations in tissue function of Merino sheep feeding on a low protein, low energy diet, the sequential measurement of a number of clinical parameters has been performed. Emphasis has been directed to the protein storage tissues, and the following indices were measured: bromsulphthalein clearance; serum levels of glutamic oxalacetic transaminase, glutamic pyruvic transaminase, total cholesterol, cholesterol esters, total proteins, electrophoretic protein fractions, and urea; urinary volume, and urine creatine, creatinine, and urea. Alterations in these indices were consistent with a marked degree of liver dysfunction occurring after several weeks on the experimental diet. No significant changes were apparent in the functional ability of kidney or muscle.

scholarly journals Effect of Low Protein and Low Energy Diet on Physiological Status and Digestibility of F344 Rats.

2002 ◽  
Vol 51 (5) ◽  
pp. 485-491 ◽  
Author(s):  
Hiroshi ITOH ◽  
Masahiro KANEKO ◽  
Seinosuke OHSHIMA ◽  
Seigo SHUMIYA ◽  
Ei SAKAGUCHI
Keyword(s):  
Low Energy ◽  
Physiological Status ◽  
Low Protein ◽  
F344 Rats ◽  
Low Energy Diet

scholarly journals Different mechanisms operating during different critical time-windows reduce rat fetal beta cell mass due to a maternal low-protein or low-energy diet

Diabetologia ◽  
2007 ◽  
Vol 50 (12) ◽  
pp. 2495-2503 ◽  
Author(s):  
O. Dumortier ◽  
B. Blondeau ◽  
B. Duvillié ◽  
B. Reusens ◽  
B. Bréant ◽  
...  
Keyword(s):  
Beta Cell ◽  
Time Windows ◽  
Cell Mass ◽  
Critical Time ◽  
Beta Cell Mass ◽  
Low Energy ◽  
Low Protein ◽  
Low Energy Diet

DIETS AND DIETARY INGREDIENTS SELECTION BY BROILER CHICKEN: EFFECTS ON GROWTH PERFORMANCE, CARCASS QUALITY AND ECONOMICS OF PRODUCTION

2021 ◽  
Vol 26 ◽  
pp. 35-42
Author(s):  
G. E. Onibi ◽  
A. P. Owoyemi ◽  
O. O. Akinyemi
Keyword(s):  
Weight Gain ◽  
Broiler Chicken ◽  
High Energy ◽  
Conversion Ratio ◽  
Feed Conversion Ratio ◽  
Low Energy ◽  
Feed Conversion ◽  
Low Protein ◽  
Choice Feeding ◽  
Low Energy Diet

A total of 90day – old Hypeco broiler chicks were used in a choice-feeding trial to investigate whether meat-type chicken could select adequate nutrients that would support fast growth rate from a choice of imbalanced diet and feed ingredients. Three diets were used: a control diet (diet A= 200g/kg CP, 3031 kcal/kg ME) and two test diets; a low protein, high-energy diet (diet B=166g/kgCP, 3021 kcal/kg ME) and a low-protein, low-energy diet (diet C=168g/kgCP, 2838 kcal/kg ME). The diets were fed singly. The test diets were also used in a choice-feeding with ground maize and soya-bean meal (SBM). The study lasted for 5weeks and the response criteria included growth performance, carcass and organ characteristics, and economics of production. Weight gain and feed conversion ratio were significantly (P < 0.01) and (P < 0.001 respectively) influenced. Birds on the control diets had the highest weight gain and best feed conversion ratio. Birds on the low-protein, high-energy diet had performances not significantly (P > 0.05) lower than the control. The low-protein, low-energy diet depressed performance. Feeding the imbalanced diets (diets B and C) singly produced better performances than feeding them with a choice of dietary ingredients. Birds exhibited selection potentials by selecting the ground maize and SBM to compensate for deficiencies in the imbalanced diets but not at a level adequate enough to improve performances. Only the relative chest weight was significantly (P < 0.05) influenced amongst the carcass and organ weights measured. It decreased with decreasing feed quality. Economics of production showed that low quality and cheaper priced feeds do not necessarily give higher income and profit. The benefits of feeding single balanced diets and the possibility of decreasing the protein content of broiler finisher diets without compromising profits were revealed. It was suggested that broiler chicken appeared to select nutrients for maximize economic performance and that feed quality control should be enforced.

Effects of a High Cholesterol–Oil Diet for Rabbits on Concentrations of Heparin and Total Sulfated Mucopolysaccharide in Aorta and Other Tissues Measured by Microelectrophoresis

1974 ◽  
Vol 52 (3) ◽  
pp. 661-668 ◽  
Author(s):  
T. K. Sue ◽  
L. B. Jaques
Keyword(s):  
Lipoprotein Lipase ◽  
Large Intestine ◽  
Serum Cholesterol ◽  
Lipase Activity ◽  
Serum Levels ◽  
Lipoprotein Lipase Activity ◽  
High Cholesterol ◽  
Experimental Diet ◽  
Small And Large Intestine

Rabbits were fed a high cholesterol–oil diet for 13 weeks. The amounts of total sulfated mucopolysaccharides and heparin in aorta, heart, skin, and small and large intestine were determined by microelectrophoresis. Aortic lipoprotein lipase activity, serum cholesterol, and triglycerides were also measured. The results showed that quantities of total sulfated mucopolysaccharides, heparin, and lipoprotein lipase activity increased markedly in aortas but were without change in other tissues in the rabbits on the experimental diet. There was a high correlation between lipoprotein lipase activity and concentrations of both heparin and total sulfated mucopolysaccharides in aorta, and also between concentrations of heparin and total sulfated mucopolysaccharides in aorta and serum levels of triglyceride and cholesterol.

MO580HYPOPROTEIC DIET SUPPLEMENTED WITH KETOANALOGUES IN PATIENTS WITH ADVANCED DIABETIC KIDNEY DISEASE – EFFECTS ON MINERAL BONE DISORDERS

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Liliana Garneata ◽  
Carmen-Antonia Mocanu ◽  
Tudor Petrisor Simionescu ◽  
Andreea Elena Mocanu ◽  
Gabriel Mircescu
Keyword(s):  
Kidney Disease ◽  
Diabetic Kidney Disease ◽  
Serum Levels ◽  
Protein Diet ◽  
Low Protein Diet ◽  
Diabetic Patients ◽  
Bone Disorders ◽  
Diabetic Kidney ◽  
Low Protein ◽  
Ckd Stage

Abstract Background and Aims Dietary protein restriction is rediscussed as mainstay approach in advanced Chronic Kidney Disease (CKD), both in diabetics and non-diabetics to defer renal replacement therapy (RRT), mainly by better metabolic control; improvements in mineral bone disorders (MBD) were also suggested, but less studied in Diabetic Kidney Disease (DKD). An unicentric prospective interventional trial aimed to assess the effects of ketoanalogue-supplemented low protein diet (sLPD) on proteinuria and CKD progression (data already presented). The parameters of MBD were also evaluated. Method Adult diabetic patients (452) with stable CKD stage 4+, proteinuria&gt;3g/g creatininuria and SGA A were enrolled in a run-in phase (3 mo), with LPD (0.6g/kg dry ideal bw). Those who proved adherent (92, 64% males, median age 55.7 yrs, 65% on insulin) received sLPD (Ketosteril®, 1 tablet/10kg) for 12mo. Monitoring and treatment followed the Best Practice Guidelines. The primary endpoint was proteinuria during intervention as compared to pre-enrolment. Serum levels of calcium, phosphates and iPTH were considered to assess MBD. Nutrition, inflammation (SGA, BMI, serum albumin, CRP) and compliance were safety parameters. Results In patients with advanced DKD and severe proteinuria, sLPD was associated with a 69 (63; 82) % reduction in proteinuria (data presented). Significant amelioration in MBD was noted: serum levels of calcium and phosphates were significantly ameliorated at the end of the study as compared to enrolment - 4.3 (4.2-4.9) vs 3.2 (3.1-3.5) mg/dL and 5.4 (4.9-6.1) vs 8.2 (7.8-8.9) mg/dL, respectively. Serum iPTH significantly decreased: 185 (168-212) vs 375 (354-585) pg/mL. The need for calcium supplementation decreased: 6.5 (6.0-6.7) vs 7.0 (6.8-7.3) g/day. Vitamin D was required by only 35% vs 65% of patients. Nutritional status was preserved and dietary compliance was very good throughout the study. Conclusion In patients with advanced DKD ketoanalogue supplemented low protein diet seems to be effective and safe as part of MBD management.

scholarly journals SP400VERY LOW PROTEIN DIET REDUCES SERUM LEVELS OF INDOXYL SULFATE AND P-CRESYL SULFATE IN CHRONIC KIDNEY DISEASE

2017 ◽  
Vol 32 (suppl_3) ◽  
pp. iii253-iii253 ◽  
Author(s):  
Maria Teresa Rocchetti ◽  
Carmela Cosola ◽  
Ighli di Bari ◽  
Lucia Di Micco ◽  
Emanuele De Simone ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Serum Levels ◽  
Indoxyl Sulfate ◽  
Protein Diet ◽  
Low Protein Diet ◽  
Low Protein
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