Studies of the effects of the gene N on body growth and fleece development of the New Zealand Romney. I. The body growth of the N type lamb

1959 ◽  
Vol 10 (3) ◽  
pp. 387 ◽  
Author(s):  
F Cockrem ◽  
AL Rae

A study has been made of the pleiotropic effects of the gene N on the body growth and the carcass of the Sew Zealand Romney lamb. Measurements of body weight and height at withers were taken from birth to about 5 months of age for lambs born in 1952 and 1953 from matings of N/+ x +/+, N/N x N/N, N/N x N/+, and N/+ x N/+ parents. In 1952, +/+ lambs grew faster than N/+ or N/N lambs and this was shown in the greater body weight of the +/+ lambs at 30 days of age. The differences in weight gains corrected for initial weight were greater for single lambs than for twin lambs. The differences in the height at withers were proportional to those in body weight except for the N/N lambs. The N/N lambs had a greater height at withers for their body weight but this could have been the result of factors other than the gene N which were associated with the N–type flock. N–type ewe lambs kept up to 18 months of age maintained lower body weights than +/+ lambs. In 1953 no differences between N/+ and +/+ lambs were found in body growth. It is suggested that a genetic-environment interaction exists for body growth and that the environmental factor is possibly one of climate. No differences were found between the carcass measurements of N/+ and +/+ ram lambs which could not be attributed to the previous differences in body growth.

1995 ◽  
Vol 147 (2) ◽  
pp. 217-223
Author(s):  
L G Moore ◽  
K P McNatty ◽  
K L Isaacs ◽  
S Lun ◽  
W Ng Chie ◽  
...  

Abstract The aim of this study was to examine the effect of the FecBB fecundity gene on plasma concentrations and pituitary content of growth hormone (GH) in sheep. No differences were found between homozygous carriers (BB) and non carriers (++) of the FecBB gene with regard to pituitary GH contents in both ovariectomized and intact ewes. However, ovariectomized ewes had higher levels of pituitary GH than intact ewes (P<0·01). There were no differences between FecBB genotypes with respect to plasma concentrations of GH in 6-year-old ovariectomized ewes bled every 10 min for 12 h or in ram lambs bled weekly during their first year of life. GH levels in the rams decreased until week 27, increased to a peak at week 31 then decreased before increasing again at week 43. Mean plasma GH concentrations in the ewe lambs bled weekly for a year decreased until week 19 then remained at approximately this level for the remainder of the year. Mean GH plasma concentrations in the ram lambs were higher than in the ewe lambs (P<0·001). Ewe lambs that were homozygous for the FecBB gene had lower body weights (P<0·05) and had higher levels of GH (P<0·01) than non carrier ewe lambs during their first year. Before the average age of first behavioural oestrus (36 weeks) GH levels in the ewe lambs were negatively correlated with body weights (r=−0·69, P<0·001, n=22). When body weight was included as a covariate in analysis of variance the genotype difference in ewe lamb plasma GH concentrations was no longer significant. In summary, pituitaries from ovariectomized ewes had higher levels of GH than those from intact ewes. There were no FecBB gene specific differences in pituitary levels of GH, the profile of plasma GH in 6-year-old ovariectomized ewes or in ram lambs during their first year of life. BB ewe lambs had higher levels of GH than ++ ewe lambs during their first year; however, this difference was probably due to the BB ewes having lower body weights than the ++ ewes because body weight was negatively correlated with mean GH levels. Journal of Endocrinology (1995) 147, 217–223


1957 ◽  
Vol 188 (3) ◽  
pp. 435-438 ◽  
Author(s):  
M. J. Fregly ◽  
N. B. Marshall ◽  
J. Mayer

Goldthioglucose-obese mice cannot adjust their food intake to meet the increased energy requirements due to cold. At all ambient temperatures above 15°C the spontaneous running activity of these animals is less than that observed for nonobese controls. Activity of obese mice is maximal at 19°C and minimal at 15°C or lower. Body weights decrease during exposure to cold. In contrast to that of obese mice, running activity of nonobese controls is maximal at an ambient temperature of 25°C but nearly ceases at 15°C or lower. The food intake of these animals increases in the cold and remains elevated even at temperatures at which activity decreases. The body weight of nonobese controls is either maintained constant or increases during exposure to cold air.


2021 ◽  
Vol 7 (1) ◽  
pp. 71-76
Author(s):  
B. I. Orji ◽  
J. Steinbach

Eleven ram lambs, all born between June and July (rainy season) were slaughtered at four age groups — 75, 100, 125 and 150 days. The body weights of animals prior to slaughter, the weights of the testes, the epididymis, the vesicular glands, the ampullae, the adrenals, the thyroids and the pituitary glands were determined and subjected to a step-wise multiple regression analysis using age or body weight as the independent variable. The weights of the reproductive organs – testes, epididymides, ampullae, vesicular glands - showed significantly higher correlation with the body weight than with the age, thus emphasizing the greater importance of the physiological age over the chronological age in the development of the body organs. The highest growth rate of the organs of the reproductive tract occurred during puberty and thus coincided with the enhanced endocrine function observed in ram lambs at this stage.


2014 ◽  
Vol 2014 ◽  
pp. 1-6
Author(s):  
Arda Yıldırım ◽  
Yüksel Aksoy ◽  
Nuh Ocak ◽  
Zafer Ulutaş

Thirty-one Karayaka ram lambs were slaughtered at different body weights (30n=7, 35n=6, 40n=7, 45n=6, and 50n=5 kg of body weight at fast) to evaluate the growth of their gastrointestinal tract (GIT) characteristics, to determine the relationship among slaughter body weight (SBW) and empty body weight (EBW), whole GIT and segments, and the influence of slaughter weight on the pH of rumen, jejunum, and cecal contents. The effects of the SBW on GIT weightP<0.05, stomachP<0.001, and intestineP<0.05, the body lengthP<0.001and caecumP<0.05, and the relative weights of GITP<0.05, stomachP<0.001, and intestineP<0.001were linear whereas that for the length of intestine were quadratic. The effect of SBW were quadraticP<0.05on ratios of stomach to GIT weight and intestine length to intestine weight and rumen pH while, for the intestine to GIT weight ratioP<0.001and caecum pHP<0.05, this effect was linear. The results indicated that for all parameters studied, with the exception of intestinal length and cecal pH, linear relationships were observed with SBW indicating steady growth rates for these tissues.


1972 ◽  
Vol 79 (1) ◽  
pp. 83-89 ◽  
Author(s):  
Ó. R. Dýrmundsson ◽  
J. L. Lees

SUMMARYSome aspects of sexual development and the attainment of puberty in Clun Forest ram lambs were studied during the two seasons 1970–1. Strong correlations existed between parameters of penial, scrotal and testicular development. Sexual development in general appeared to be more closely associated with the body growth than the chronological age of the ram lamb.Nevertheless, marked variation existed in both age and body weight at puberty. Although the majority of the lambs attained this stage of development at 4·5–5 months the age-range extended from 99 to 176 days. The mean body weight at puberty was 32·5 kg, ranging from 24·5 to 38·0 kg. There appeared to be an interaction between chronological age and general body development in relation to the appearance of sperm in the epididymides. Not only did it seem that a certain degree of body growth and testicular size was required before spermatozoa could be released, but also a limit of chronological age below which puberty was not attained. Large differences existed between individual lambs in both testicular and epididymal weights at puberty. There was a high degree of symmetry in growth between the left and the right testes and epididymides.Time of birth influenced the pattern and rate of body growth and sexual development. This seemed to be largely due to seasonal fluctuations in nutritional conditions during rearing but the results obtained do not preclude the possibility that other seasonal factors, such as the daylight environment experienced by the ram lamb, might have a certain limited influence on sexual development.


2021 ◽  
Vol 888 (1) ◽  
pp. 012010
Author(s):  
F Mustofa ◽  
A P Z N L Sari ◽  
E Suryanto ◽  
D Maharani ◽  
A Agus ◽  
...  

Abstract Body weight is a critical parameter to monitor in chickens due to its correlation with better performance during the production phase. Hence, this study aimed to present an overview of the body weight performance of indigenous Indonesian chickens in the grower phase. The study was conducted in Gunung Kidul, Yogyakarta. Data of body weight performance data of 227 Merawang, 157 Murung Panggang, and 416 KUB chickens in the grower phase were collected. These weights were measured 4 times at 6, 8, 10, and 12 weeks while rearing the chickens in battery cages in a closed house under similar management. The result showed that the Murung Panggang chickens at each age had the highest body weight and uniformity value (P<0.05), followed by Merawang and KUB. The body growth curve of the Merawang, Murung Panggang, and KUB chickens at the 6th week showed similar weights, ranging between 400-600 g. However, at the 8th, 10th, and 12th weeks, the Merawang and Murung Panggang chickens had higher body weight performance. Therefore, this study suggested that Merawang and Murung Panggang chickens may have a greater potential to attain higher final body weights.


Author(s):  
O. Derewicka ◽  
D. Maj ◽  
S. Pałka ◽  
J. Bieniek

The aim of the study was to determine the effect of genotypes on the growth and slaughter traits of Burgundy Fawn (BF), Flemish Giant (FG) and New Zealand White (NZW) rabbits and their crosses. Body weight was recorded from birth to slaughter on the 84th day of life. On the 84thday of life, significantly smaller body weight was recorded in pure bred NZW rabbits (2116 g), while the body weights of purebred FG rabbits (2957 g) were significantly heavier than rabbits with other genotypes. The highest dressing out percentage was obtained for BF rabbits and for BF × FG crosses. It was found that crossing of BF or NZW females with FG males results in a high final body weight and dressing out percentage; therefore, such crossing should be recommended for the production of slaughter rabbits.


Author(s):  
Barbara Hammer ◽  
Latha Kadalayil ◽  
Eistine Boateng ◽  
Dominik Buschmann ◽  
Faisal I. Rezwan ◽  
...  

Abstract Background Active smoking has been reported among 7% of teenagers worldwide, with ages ranging from 13 to 15 years. An epidemiological study suggested that preconceptional paternal smoking is associated with adolescent obesity in boys. We developed a murine adolescent smoking model before conception to investigate the paternal molecular causes of changes in offspring’s phenotype. Method Male and female C57BL/6J mice were exposed to increasing doses of mainstream cigarette smoke (CS) from onset of puberty for 6 weeks and mated with room air (RA) controls. Results Thirteen miRNAs were upregulated and 32 downregulated in the spermatozoa of CS-exposed fathers, while there were no significant differences in the count and morphological integrity of spermatozoa, as well as the proliferation of spermatogonia between CS- and RA-exposed fathers. Offspring from preconceptional CS-exposed mothers had lower body weights (p = 0.007). Moreover, data from offspring from CS-exposed fathers suggested a potential increase in body weight (p = 0.062). Conclusion We showed that preconceptional paternal CS exposure regulates spermatozoal miRNAs, and possibly influences the body weight of F1 progeny in early life. The regulated miRNAs may modulate transmittable epigenetic changes to offspring, thus influence the development of respiratory- and metabolic-related diseases such as obesity, a mechanism that warrants further studies for elaborate explanations.


2014 ◽  
Vol 84 (1-2) ◽  
pp. 5-11 ◽  
Author(s):  
Eun Y. Jung ◽  
Sung C. Jun ◽  
Un J. Chang ◽  
Hyung J. Suh

Previously, we have found that the addition of L-ascorbic acid to chitosan enhanced the reduction in body weight gain in guinea pigs fed a high-fat diet. We hypothesized that the addition of L-ascorbic acid to chitosan would accelerate the reduction of body weight in humans, similar to the animal model. Overweight subjects administered chitosan with or without L-ascorbic acid for 8 weeks, were assigned to three groups: Control group (N = 26, placebo, vehicle only), Chito group (N = 27, 3 g/day chitosan), and Chito-vita group (N = 27, 3 g/day chitosan plus 2 g/day L-ascorbic acid). The body weights and body mass index (BMI) of the Chito and Chito-vita groups decreased significantly (p < 0.05) compared to the Control group. The BMI of the Chito-vita group decreased significantly compared to the Chito group (Chito: -1.0 kg/m2 vs. Chito-vita: -1.6 kg/m2, p < 0.05). The results showed that the chitosan enhanced reduction of body weight and BMI was accentuated by the addition of L-ascorbic acid. The fat mass, percentage body fat, body circumference, and skinfold thickness in the Chito and Chito-vita groups decreased more than the Control group; however, these parameters were not significantly different between the three groups. Chitosan combined with L-ascorbic acid may be useful for controlling body weight.


2020 ◽  
Vol 20 (8) ◽  
pp. 1262-1267
Author(s):  
Haojun Yang ◽  
Hanyang Liu ◽  
YuWen Jiao ◽  
Jun Qian

Background: G protein-coupled bile acid receptor (TGR5) is involved in a number of metabolic diseases. The aim of this study was to identify the role of TGR5 after Roux-en-Y gastric bypass (GBP). Methods: Wild type and TGR5 knockout mice (tgr5-/-) were fed a high-fat diet (HFD) to establish the obesity model. GBP was performed. The changes in body weight and food intake were measured. The levels of TGR5 and peptide YY (PYY) were evaluated by RT-PCR, Western blot, and ELISA. Moreover, the L-cells were separated from wild type and tgr5-/- mice. The levels of PYY in L-cells were evaluated by ELISA. Results: The body weights were significantly decreased after GBP in wild type mice (p<0.05), but not tgr5-/- mice (p>0.05). Food intake was reduced after GBP in wild type mice, but also not significantly affected in tgr5-/- mice (p>0.05). The levels of PYY were significantly increased after GBP compared with the sham group (p<0.05); however, in tgr5-/- mice the expression of PYY was not significantly affected (p>0.05). After INT-777 stimulation in L-cells obtained from murine intestines, the levels of PYY were significantly increased in L-cells tgr5+/+ (p<0.05). Conclusion: Our study suggests that GBP up-regulated the expression of TGR5 in murine intestines, and increased the levels of PYY, which further reduced food intake and decreased the body weight.


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