scholarly journals Immunisation against gonadotrophin-releasing hormone (GnRH) reduces agonistic behaviours in male rangeland goats

2016 ◽  
Vol 56 (11) ◽  
pp. 1882 ◽  
Author(s):  
Catherine C. Bishop ◽  
Patricia A. Fleming ◽  
Anne L. Barnes ◽  
Teresa Collins ◽  
David W. Miller
Keyword(s):  
Social Stress ◽  
Body Condition Score ◽  
Control Group ◽  
Agonistic Interactions ◽  
Testosterone Concentration ◽  
Releasing Hormone ◽  
Sterile Saline ◽  
Scrotal Circumference ◽  
Condition Score ◽  
Gonadotrophin Releasing Hormone

Rangeland goat bucks were used to evaluate the efficacy of a commercially available anti-gonadotrophin-releasing hormone vaccine, Improvac (Zoetis Australia, West Ryde, NSW, Australia). The hypothesis tested was that immunisation would suppress testosterone secretion by the testis and agonistic behaviour between male goats. We also compared intervals of 2 and 4 weeks between primary and booster immunisations and monitored responses over a 2-month period. The 45 goats were split into three groups (n = 15): one group receiving the vaccination booster on Day 14, one group receiving the vaccination booster on Day 28, and the Control group receiving sterile saline injections. Body mass, body condition score and scrotal circumference were measured fortnightly, and blood was collected at 2-week intervals and analysed for testosterone concentration. Behavioural interaction tests of 2-min duration were also conducted fortnightly. There was a significant decrease in paired testicular circumference (P < 0.05) and testosterone concentration (P < 0.01) in both vaccination groups by the end of the experiment at Day 60, compared with the Control group. Agonistic interactions measured at Day 60 were significantly reduced in both vaccination groups (P < 0.05) compared with the Control group. These results support the efficacy of Improvac in reducing agonistic behaviours in rangeland goat bucks and suggest that the use of the vaccine may assist in reducing social stress and possible injury in groups of confined male goats.

101 Treatment with gonadotrophin-releasing hormone on Day 7 or 21 does not reduce pregnancy loss in dairy heifers receiving invitro-produced embryos

2020 ◽  
Vol 32 (2) ◽  
pp. 176
Author(s):  
B. J. Duran ◽  
R. V. Sala ◽  
P. L. J. Monteiro ◽  
C. Gamarra ◽  
M. Fosado ◽  
...  
Keyword(s):  
Embryo Transfer ◽  
Pregnancy Loss ◽  
Body Condition Score ◽  
Prostaglandin F2α ◽  
P Value ◽  
Releasing Hormone ◽  
Dairy Heifers ◽  
Condition Score ◽  
Pregnancy Status ◽  
Gonadotrophin Releasing Hormone

Previous research has shown that induction of an accessory corpus luteum (CL) by administration of gonadotrophin-releasing hormone (GnRH) on Day 5 increases circulating progesterone and reduces pregnancy loss between Days 33 and 60 in heifers receiving invitro-produced (IVP) embryos. Therefore, the objective of the present study was to determine whether timing of induction of an accessory CL influenced pregnancy loss in IVP recipients. Holstein heifers (n=1,658) were synchronized using a modified 5-day CIDR CO-Synch protocol. Briefly, heifers received an intravaginal progesterone device (CIDR) on Day −8, Day −3: CIDR removed and first prostaglandin F2α (PGF2α) treatment, Day −2: second PGF2α, and Day 0: GnRH (G1, 100µg of gonadorelin acetate). Oestrus expression was evaluated on Day 0 with the use of an oestrus detection device. Transfer of fresh IVP embryos was performed on Day 7±1 after G1. At the time of transfer, heifers were randomly assigned, in a 2×2 factorial design, to receive GnRH (200µg of gonadorelin acetate) or remain as Control (untreated) at two different times: Day 7 (time of embryo transfer (ET)) or Day 21. Thus, the following groups were formed: Control-Control (n=410); Control-GnRH (n=409); GnRH-Control (n=419); and GnRH-GnRH (n=420). All heifers were evaluated by transrectal ultrasonography to determine number, size, and location of CL on Days 5, 14, 21, 28, 32, and 60 and pregnancy status on Days 28, 32, and 60. Data collected from each heifer included embryo stage and quality, oestrus expression, body condition score, number of transfers, and technician. Pregnancies per embryo transfer (P/ET) and pregnancy loss data were analysed by logistic regression (SAS 9.4). Ovulation to Day 7 treatment was greater (P&lt;0.01) in GnRH treated heifers (70.0%; 585 out of 836) than in untreated Controls (2.7%; 22 of 819). Ovulation to Day 21 treatment was determined only in animals pregnant at Day 28 and was greater (P&lt;0.01) in heifers treated with GnRH (37.6%; 153 of 407) than in untreated controls (1.0%; 4 of 390). There was no effect of Day 7 treatment (P&gt;0.68) or Day 21 treatment (P&gt;0.18), nor a Day 7×Day 21 treatment interaction (P&gt;0.48) on P/ET at Day 32 or 60 (Table 1). Treatment with GnRH on Day 7 or 21 did not alter pregnancy loss between Days 32 and 60 (P&gt;0.10). Heifers with an accessory CL present at Day 32 (11.7%; 41 of 350) had similar (P=0.55) pregnancy loss compared with heifers with no accessory CL (14.4%; 54 of 375). The number of CL present on Day 32 did not affect (P=0.23) pregnancy loss; however, heifers with 3 CL (4.9%; 3 of 61) tended (P&lt;0.10) to have reduced pregnancy loss compared with heifers with 1 CL (14.4%; 54 of 375) or 2 CL (13.2%; 38 of 289). In conclusion, treatment with GnRH on Day 7 or 21 induced an accessory CL; however, it did not affect P/ET on Days 32 or 60 and pregnancy loss. Table 1.Pregnancies per embryo transfer (P/ET) and pregnancy loss in embryo recipients based on timing of treatment with gonadotrophin-releasing hormone (GnRH) Treatment P/ET Day 32% (n) P/ET Day 60% (n) Pregnancy loss% (n) Day 7 Day 21 Control Control 42.4 (410) 36.1 (410) 15.0 (174) GnRH 46.0 (409) 40.7 (409) 11.7 (188) GnRH Control 43.7 (419) 36.8 (419) 15.9 (183) P-value GnRH 43.1 (420) 38.8 (420) 10.0 (181) Day 7 treatment 0.68 0.72 0.96 Day 21 treatment 0.51 0.18 0.11 Interaction 0.48 0.66 0.71

Effect of pretreatment with insulin on the response of buffaloes with inactive ovaries to gonadotrophin-releasing hormone agonist treatment in summer

2007 ◽  
Vol 19 (2) ◽  
pp. 351 ◽  
Author(s):  
Adel A. Ramoun ◽  
Khalid T. Osman ◽  
Samy A. Darwish ◽  
Aly M. Karen ◽  
Magdy H. Gamal
Keyword(s):  
Intramuscular Injection ◽  
Control Group ◽  
Dominant Follicle ◽  
Once Daily ◽  
Releasing Hormone ◽  
Sterile Saline ◽  
Induction Rate ◽  
Gonadotrophin Releasing Hormone ◽  
Egyptian Buffalo ◽  
Buffalo Cow

The aim of the present study was to evaluate the effect of a pretreatment with insulin on the response of buffalo cows with inactive ovaries to gonadotrophin-releasing hormone agonist (GnRHa) treatment during hot summer months (July and August). Thirty-six Egyptian buffalo cows with inactive ovaries were randomly allocated into three groups: (1) group treated with GnRHa (G1, n = 16) in which each buffalo received an intramuscular injection of 250 mg of GnRHa (Day 0; gonadorelin, Fertagyl); (2) group treated with insulin before the GnRHa injection (G2, n = 8) in which each buffalo received a subcutaneous injection of biphasic insulin at a dose of 0.25 IU kg–1 bodyweight once daily starting at Day –3 for 3 consecutive days, followed by an intramuscular injection of 250 mg of GnRHa on Day 0; and (3) the control group (G3, n = 12) in which each buffalo cow received an intramuscular injection of 2.5 mL of sterile saline on Day 0. The ovaries of all animals were examined by trans-rectal ultrasonography (5 MHz) on Days –7, –3 and 0 and continued thereafter at 4-day intervals until oestrus or the end of the experiment. On the same days that ultrasound examinations were performed blood samples were collected to measure the progesterone concentrations. Administration of insulin for 3 days before GnRHa injection (G2) significantly (P < 0.05) increased the diameter of the largest follicle from 6.85 ± 0.64 to 12.4 ± 0.88 mm. There was a significant (P < 0.01) increase in the oestrous induction rate in G2 compared with both G1 and G3 during the first 12 days after the treatment interval. It is concluded that pretreatment with insulin for 3 days before GnRHa injection increases the diameter of the dominant follicle and therefore the oestrous induction rate of acyclic buffaloes.

scholarly journals Effects of a synthetic gonadotrophin-releasing hormone agonist, leuprolide, on rut-associated events in male red deer

2009 ◽  
Vol 49 (12) ◽  
pp. 1120 ◽  
Author(s):  
G. K. Barrell ◽  
S. C. T. Schaafsma ◽  
M. J. Ridgway ◽  
M. Wellby ◽  
L. A. Miller
Keyword(s):  
Cervus Elaphus ◽  
Red Deer ◽  
Body Condition Score ◽  
Plasma Testosterone ◽  
High Dose ◽  
Release Formulation ◽  
Releasing Hormone ◽  
Condition Score ◽  
Gonadotrophin Releasing Hormone ◽  
Farming Industry

This study examined the effectiveness of leuprolide, a gonadotrophin-releasing hormone agonist, in suppressing rut-associated events in farmed male red deer. In mid-January (~6 weeks before the rut period in the southern hemisphere) adult red deer (Cervus elaphus scoticus) stags that had been allocated to three groups (n = 10 per group) received leuprolide, administered subcutaneously in a 90-day release formulation, at zero (control), low (22.5 mg) or high (45 mg) doses. Following treatment with leuprolide there was evidence of suppression of mean plasma luteinising hormone concentration that was significant (P < 0.05) at 9 weeks. Mean plasma testosterone concentration of all three groups rose following treatment, then declined prematurely in the low- and high-dose leuprolide-treated groups, so that it was significantly (P < 0.05) suppressed (0.66 ± 0.29 and 2.0 ± 0.88 ng mL–1, low and high dose respectively) in early April when the peak value (9.0 ± 1.94 ng mL–1) was recorded from control stags. A reduction in mean liveweight occurred in all three groups through February–April and this did not differ among treatments. However, a corresponding reduction in mean body condition score was greater in the control stags (P < 0.05). There was little effect of leuprolide treatment on aggressive behaviours, but it lowered roaring frequency in the latter period of the rut. The results indicate that this gonadotrophin-releasing hormone agonist has potential for application in the deer farming industry to suppress undesirable effects of the rut.

scholarly journals Safety Study on Ketoprofen in Pigs: Evaluating the Effects of Different Dosing and Treatment Scheme on Hematological, Hepatic, and Renal Parameters

2021 ◽  
Vol 8 (2) ◽  
pp. 30
Author(s):  
Luis Emilio Fazzio ◽  
Santiago José Raggio ◽  
Juan Facundo Romero ◽  
Juver Membrebe ◽  
Antonio Humberto Hamad Minervino
Keyword(s):  
Body Condition Score ◽  
Clinical Signs ◽  
Study Groups ◽  
Control Group ◽  
Safety Study ◽  
Treatment Groups ◽  
Treatment Scheme ◽  
Condition Score ◽  
Biochemical Evaluation ◽  
Different Doses

A safety study on ketoprofen 10% was carried out on pigs using a different dosing and treatment scheme. Forty healthy crossbreed pigs with similar age, weight, and body condition score were distributed into five treatment groups. The pigs were intramuscularly injected once with different doses of ketoprofen: 3 mg/kg (group 1X), 6 mg/kg (group 2X), 9 mg/kg (group 3X). In addition, the 3 mg/kg dosis was administered on three consecutive days (group 1X ext.). Intramuscular injections of saline solution were used in control group (CTL). The pigs were clinically examined throughout the trial and blood samples were taken for hematological and biochemical evaluation on days −4 (before treatment), +3, +7, and +14 (the end of the trial). Any unusual behaviour or clinical signs were reported as potential toxic effects of ketoprofen. Serum measurements showed that none of the ketoprofen doses produced changes in renal or hepatic biochemical parameters, liver enzymes, or total bilirubin. Likewise, hematological assessment indicated no altered parameters or hematocrit percentage in the study groups. These results demonstrate that ketoprofen has no adverse effects in pigs when the doses and scheme evaluated in this study are applied.

scholarly journals Luteogenesis and Embryo Implantation Are Enhanced by Exogenous hCG in Goats Subjected to an Out-of-Season Fixed-Time Artificial Insemination Protocol

Biology ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 429
Author(s):  
Jorge A. Bustamante-Andrade ◽  
César A. Meza-Herrera ◽  
Rafael Rodríguez-Martínez ◽  
Zurisaday Santos-Jimenez ◽  
Oscar Ángel-García ◽  
...  
Keyword(s):  
Corpus Luteum ◽  
Artificial Insemination ◽  
Body Condition Score ◽  
Embryo Implantation ◽  
Implantation Rate ◽  
Fixed Time ◽  
Efficiency Index ◽  
Control Group ◽  
Condition Score ◽  
Interesting Approach

The aim of this study was to evaluate the possible effect of two doses of hCG (100 and 300 IU) applied at two different times (7 and 14 d) after a fixed-time artificial insemination protocol (FTAI) upon some variables involved in the embryonic implantation rate in goats during the natural deep anestrous season (April, 25° north). The experimental units considered crossbred, multiparous, anovulatory goats (n = 69, Alpine, Saanen, Nubian x Criollo), with average body weight (43.6 ± 5.7 kg) and body condition score (1.86 ± 0.28 units) located in northern–semiarid Mexico (25° N, 103° W). Once the goat’s anestrus status was confirmed, goats were subjected to an estrus induction protocol. Upon estrus induction confirmation, goats (n = 61) were subjected to a FTAI procedure. Immediately after the FTAI, the goats were randomly distributed to five experimental groups: (1). G100-7 (n = 13) 100 IU, hCG 7 d post-FTAI, (2). G100-14 (n = 12) 100 IU hCG, 14 d post-FTAI, (3). G300-7 (n = 12) 300 IU, hCG, 7 d post-FTAI, (4). G300-14 (n = 12) 300 IU hCG 14 d post-FTAI, and (5). Control group, CONT (n = 12) 0.5 mL saline, 7 and 14 d post-FTAI. The response variables conception rate (39.36 ± 0.23), fertility rate (27.96%), prolificacy rate (1.1 ± 0.29 kids), ovulation rate (0.74 ± 0.20 corpus luteum) corpus luteum diameter (10.15 ± 0.59 mm), embryo number (1.58 ± 0.20), and embryo implantation rate (48.96%), did not differ between treatments. However, while the variables fecundity rate (67%), embryo efficiency index-1 (33.99 ± 0.20%), and embryo efficiency index-2 (27.94 ± 0.30%) were favored by the G300-14 treatment, the corpus luteum area was favored (p < 0.05) by both G300-7 (113.30 ± 0.19 mm2) and G300-14 (103.04 ± 0.17 mm2). Such reproductive strategy emerges as an interesting approach, not only to enhance the out-of-season reproductive outcomes, but also to boost one of the main rulers defining the global reproductive efficiency of a heard, namely, the embryo implantation efficiency.

Male traits and herd reproductive capability in tropical beef cattle. 2. Genetic parameters of bull traits

2013 ◽  
Vol 53 (2) ◽  
pp. 101 ◽  
Author(s):  
N. J. Corbet ◽  
B. M. Burns ◽  
D. J. Johnston ◽  
M. L. Wolcott ◽  
D. H. Corbet ◽  
...  
Keyword(s):  
Body Condition ◽  
Semen Quality ◽  
Body Condition Score ◽  
Progressive Motility ◽  
Scrotal Circumference ◽  
Normal Sperm ◽  
Igf I ◽  
Condition Score ◽  
Mass Activity ◽  
Percent Normal

A total of 4063 young bulls of two tropical genotypes (1639 Brahman and 2424 Tropical Composite) raised in northern Australia were evaluated for a comprehensive range of production and reproduction traits up to 24 months of age. Prior to weaning, peripheral blood concentrations of luteinising hormone (LH) and inhibin were measured at 4 months of age. At weaning (6 months) blood insulin-like growth factor-1 (IGF-I) and flight time were recorded. Body composition traits of fat depth and eye-muscle area were determined by ultrasonography at 15 months of age when additional measurements of liveweight, hip height and body condition score were recorded. Bull breeding soundness was evaluated at ~12, 18 and 24 months of age when measurements of scrotal circumference, sheath score, semen mass activity, progressive motility of individual sperm and percent morphologically normal sperm were recorded. Magnitude of heritability and genetic correlations changed across time for some traits. Heritability of LH, inhibin, IGF-I and of 18-month scrotal circumference, mass activity, progressive motility and percent normal sperm was 0.31, 0.74, 0.44, 0.75, 0.24, 0.15 and 0.25, respectively, for Brahmans and 0.48, 0.72, 0.36, 0.43, 0.13, 0.15 and 0.20, respectively, for Tropical Composites. Inhibin and IGF-I had moderate genetic association with percent normal sperm at 24 months in Brahmans but low to negligible associations in Tropical Composites. Body condition score in Brahmans and sperm motility (mass and individual) traits in both genotypes had moderate to strong genetic correlation with percent normal sperm and may prove useful candidates for indirect selection. There is scope to increase scrotal circumference by selection and this will be associated with favourable correlated responses of improved semen quality in both genotypes. The lack of genetic antagonism among bull traits indicates that selection for improved semen quality will not adversely affect other production traits.

scholarly journals Tylosin injectable for the treatment of porcine proliferative enteropathy in experimentally inoculated pigs

2019 ◽  
Vol 39 (3) ◽  
pp. 168-174
Author(s):  
Luisa V.A. Otoni ◽  
Michelle P. Gabardo ◽  
Núbia R. Macêdo ◽  
Mariane M. Wagatsuma ◽  
Marina M. Pereira ◽  
...  
Keyword(s):  
Body Condition Score ◽  
Initial Period ◽  
Etiologic Agent ◽  
Economic Losses ◽  
Control Group ◽  
Lawsonia Intracellularis ◽  
Medication Group ◽  
Proliferative Enteropathy ◽  
Condition Score ◽  
And Control

ABSTRACT: Porcine proliferative enteropathy (PPE) is one of the most common enteric diseases in growing and finishing pigs. PPE is characterized by reduced growth performance, accompanied or not by diarrhea. PPE is highly prevalent in several countries of the Americas, Europe and Asia, causing high economic losses in swine herds. The most common form of PPE control in pigs is antibiotic therapy. The objective of this study was to evaluate a new product based on tylosin injectable (Eurofarma Laboratórios S.A.) to control PPE in experimentally inoculated animals. Sixty 5-week-old pigs with mean weight of 9.5kg were divided into two experimental groups of 30 animals: medication and control. All pigs were challenged with Lawsonia intracellularis, the etiologic agent of PPE, on day zero. Fecal score, body condition score, and behavior were daily evaluated. Pigs were weighted on days -2, 13 and 21 of the experiment. Pigs in the Medication Group received tylosin injectable 13 days after inoculation, in three doses with a 12-hour interval between them. Pigs in the Control Group received injectable saline solution following the same protocol. In the Control Group, 23pigs presented with diarrhea before day 13. After day 13, the number of diarrheic animals in this group was reduced to 17. In the Medication Group, 26 pigs presented with diarrhea in the initial period, and in the period after medication, only 11 animals had diarrhea. The score of gross intestinal PPE lesions in the Medication Group was lower than that in the Control Group (p=0.031). The Medication Group also showed lower score for Lawsonia intracellularis antigen-labeling by immunohistochemistry compared with that of the Control Group (p=0.032), showing lower level of infection. These results demonstrate that tylosin injectable (Eurofarma Laboratórios S.A.), administrated in three doses (1mL/20kg) every 12 hours, was effective for the control of PPE in experimentally inoculated pigs.

Genetic aspects of body weight, body condition score, scrotal circumference and reproductive performance in Italian Holstein young bulls

2003 ◽  
Vol 2003 ◽  
pp. 53-53 ◽  
Author(s):  
S. Biffani ◽  
A.B. Samoré ◽  
F. Canavesi ◽  
E. Olzi ◽  
M. Cassandro
Keyword(s):  
Body Weight ◽  
Body Condition ◽  
Reproductive Performance ◽  
Body Condition Score ◽  
Point Of View ◽  
Progeny Testing ◽  
Scrotal Circumference ◽  
Good Physical Condition ◽  
Condition Score ◽  
Recessive Genes

Apart from all the issues regarding health and undesirable recessive genes, which are determining factors to identify bulls not suitable for AI, there are other aspects which can be considered. The principal aims of AI studs are the selection of the best animals from a genetic point of view and the production of semen in a very short time, in order to start progeny testing as soon as possible. In Italy progeny testing starts when 1200 straws for each young bull are available. This requirement implies that bulls should be in good physical condition. According to this, the genetic centre of the Italian Holstein Breeder Association (ANAFI) has been paying growing attention to animal welfare and fitness, recording routinely some biometrical indicators. Body weight (BW), scrotal circumference (SC), body condition score (BCS) are some examples of this policy and could be helpful and easy predictors of reproductive performance for a young progeny testing dairy bull. The objective of this report was to conduct a preliminary analysis on the genetic aspects of BW, BCS, SC, age at the 1st usable straw (AGE1) and age at the 1200th straw (AGE1200) in Italian Holstein young bulls.

Effect of the body condition of ewes on the secretion of LH and FSH and the pituitary response to gonadotrophin-releasing hormone

1989 ◽  
Vol 120 (3) ◽  
pp. 497-502 ◽  
Author(s):  
S. M. Rhind ◽  
S. McMillen ◽  
W. A. C. McKelvey ◽  
F. F. Rodriguez-Herrejon ◽  
A. S. McNeilly
Keyword(s):  
Body Condition ◽  
Luteal Phase ◽  
Body Condition Score ◽  
Pulse Amplitude ◽  
Ovarian Hormones ◽  
Pulse Frequency ◽  
Follicular Phase ◽  
High Body ◽  
Condition Score ◽  
Gonadotrophin Releasing Hormone

ABSTRACT The effects of body fat content (body condition) of ewes on hypothalamic activity and gonadotrophin-releasing hormone (GnRH) secretion and on pituitary sensitivity to GnRH were investigated using Scottish Blackface ewes. Two groups of 12 ewes were fed so that they achieved either a high body condition score (2·98, s.e.m. = 0·046; approximately 27% of empty body weight as fat) or a low body condition score (1·94, s.e.m. = 0·031; approximately 19% of empty body weight as fat) by 4 weeks before the period of study. Thereafter, they were differentially fed so that the difference in mean condition score was maintained. Oestrus was synchronized, and on day 11 of the subsequent cycle half of the ewes of each group were ovariectomized. On day 12, the remaining ewes were injected (i.m.) with 100 μg prostaglandin F2α analogue and ovariectomized 30 h later. Numbers of large ovarian follicles and corpora lutea present at ovariectomy were recorded. Blood samples were collected at 15-min intervals for 12 h on day 10 of the cycle (luteal phase) and at 10-min intervals from 24 to 30 h after prostaglandin injection (follicular phase). At days 2 and 7 after ovariectomy, samples were collected at 15-min intervals for 8 h and ewes were then injected with 10 μg GnRH and samples were collected for a further 3 h. Samples were assayed for LH and FSH. Ewes in high body condition had more more large follicles than ewes in low body condition during the luteal phase (15·3 vs 6·5; P < 0·05) and follicular phase (11·5 vs 7·0; NS) and a slightly higher mean ovulation rate (1·50 vs 1·20; NS). However, during the luteal and follicular phases of the cycle before ovariectomy there was no effect of condition score on mean LH or FSH concentrations or mean LH pulse frequency or pulse amplitude. Two days after ovariectomy, ewes of high body condition had a higher mean LH pulse frequency than ewes of low body condition (P < 0·05) and higher mean FSH concentrations (P < 0·05). Mean LH concentration and pulse amplitude were not affected. LH and FSH profiles were not affected by body condition on day 7. GnRH-induced increases in LH and FSH concentrations on days 2 and 7 were not affected by body condition. At day 7, but not day 2, ewes ovariectomized during the luteal phase of the cycle had a significantly (P < 0·05) greater GnRH-induced LH release compared with ewes ovariectomized during the follicular phase. It is concluded that body condition directly affects hypothalamic activity and GnRH secretion, but not pituitary sensitivity to GnRH, and that effects on reproductive performance are also mediated through changes in ovarian hormones or in hypothalamo-pituitary sensitivity to ovarian hormones. Journal of Endocrinology (1989) 120, 497–502

Effect of α-tocopherol acetate and zinc supplementation on body condition, energy metabolites and milk production in Karan Fries cows

2016 ◽  
Vol 50 (1) ◽  
Author(s):  
Pankaj Kumar Maurya ◽  
Anjali Aggarwal ◽  
A. K. Singh ◽  
B. K. Chaudhari
Keyword(s):  
Body Weight ◽  
Treatment Group ◽  
Milk Production ◽  
Body Condition ◽  
Body Condition Score ◽  
Control Group ◽  
Experimental Animals ◽  
Tocopherol Acetate ◽  
Condition Score ◽  
Karan Fries

The study was conducted to investigate the effect of α-tocopherol acetate and zinc on body condition, energy metabolites and milk production in Karan Fries cows. Sixteen pregnant Karan Fries cows were selected two months before expected date of calving. The experimental animals were randomly divided in to two groups namely control group (eight cows) and treatment group (eight cows). Treatment group cows were supplemented with α-tocopherol acetate @ 1000 IU/day/cow and zinc @ 60 ppm/day/cow. Blood samples were collected on the days -60, -45, -30, -15, -7, 0, +7, +15, +30, +45 and +60 with respect to expected date of calving. The body weight and body condition score of all the experimental animals was recorded on the day of blood collection. After calving milk yield of the experimental animals was recorded till 60 days in milk. At parturition, body weight and body condition score differ significantly (P<0.001) in treatment group than control group (448.00 vs. 416.33 Kg and 4.42 vs. 4.17, respectively). The overall mean (±SEM) of plasma glucose was found to be significantly (P<0.001) higher in treatment group as compared to control group (62.39±1.23 vs. 57.44±1.59 mg/dl). The overall mean of non-esterified fatty acids was found to be significantly (P<0.001) lower in treatment group as compared to control group (197.10±3.38 vs. 239.21±3.48 μM/L). The overall mean of milk yield was found significantly (P<0.001) higher in treatment group as compared to control group (20.48±1.16 vs. 16.94±1.38 Kg/day i.e. 20.90%). The results of this study indicated that supplementation of antioxidants like α-tocopherol acetate and zinc have beneficial effects on milk production along with improved body condition and metabolic status of the animals.

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