Visual function in breast-fed term infants weaned to formula with or without long-chain polyunsaturates at 4 to 6 months: A randomized clinical trial

2003 ◽  
Vol 142 (6) ◽  
pp. 669-677 ◽  
Author(s):  
Dennis R. Hoffman ◽  
Eileen E. Birch ◽  
Yolanda S. Castañeda ◽  
Sherry L. Fawcett ◽  
Dianna H. Wheaton ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Visual Function ◽  
Term Infants ◽  
Breast Fed ◽  
Long Chain

Dietary Long-Chain Polyunsaturated Fatty Acids Do Not Influence Growth of Term Infants: A Randomized Clinical Trial

PEDIATRICS ◽  
1999 ◽  
Vol 104 (3) ◽  
pp. 468-475 ◽  
Author(s):  
Maria Makrides ◽  
Mark A. Neumann ◽  
Karen Simmer ◽  
Robert A. Gibson
Keyword(s):  
Clinical Trial ◽  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Randomized Clinical Trial ◽  
Term Infants ◽  
Long Chain

scholarly journals Reduced crying in term infants fed high beta-palmitate formula: a double-blind randomized clinical trial

2014 ◽  
Vol 14 (1) ◽  
Author(s):  
Ita Litmanovitz ◽  
Fabiana Bar-Yoseph ◽  
Yael Lifshitz ◽  
Keren Davidson ◽  
Alon Eliakim ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Double Blind ◽  
Term Infants ◽  
High Beta

Influence of Feeding Types during the First Months of Life on Calciuria Levels in Healthy Infants: A Secondary Analysis from a Randomized Clinical Trial

2017 ◽  
Vol 70 (2) ◽  
pp. 132-139 ◽  
Author(s):  
Natalia Ferré ◽  
Carmen Rubio-Torrents ◽  
Veronica Luque ◽  
Ricardo Closa-Monasterolo ◽  
Veit Grote ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Dietary Factors ◽  
Calcium Excretion ◽  
Dietary Intakes ◽  
Linear Regression Models ◽  
Term Infants ◽  
Spot Urine ◽  
Feeding Types ◽  
Healthy Infants

Background/Aims: Dietary factors can modify calciuria. We aim to investigate urinary calcium excretion in healthy infants according to their protein. Methods: Secondary data analysis from a randomized clinical trial where healthy term infants were randomized after birth to a higher (HP) or lower (LP) protein content formula that was consumed until age 1 year. A non-randomized group of breastfed (BF) infants was used for reference. Anthropometry, dietary intakes and calciuria (calcium/creatinine ratios) from spot urine samples were assessed at ages 3 and 6 months. At 6 months, the kidney volumes were assessed using ultrasonography, and the serum urea and creatinine levels were determined. Results: BF infants showed the highest calciuria levels, followed by the HP and the LP groups (p < 0.001 for all comparisons). Either protein intakes or formula types modulated the calciuria in linear regression models adjusted for other influencing dietary factors. The usual cut-off values classified 37.8% (BF), 16.8% (HP) and 4.9% (LP) of the infants as hypercalciuric. Conclusions: Feeding types during the first months of life affect calciuria, with BF infants presenting the highest levels. We propose new cut-off values, based on feeding types, to prevent the overestimation in hypercalciuria diagnoses among BF infants.

scholarly journals The Groningen LCPUFA study: no effect of postnatal long-chain polyunsaturated fatty acids in healthy term infants on neurological condition at 9 years

2010 ◽  
Vol 104 (4) ◽  
pp. 566-572 ◽  
Author(s):  
Corina de Jong ◽  
Hedwig K. Kikkert ◽  
Vaclav Fidler ◽  
Mijna Hadders-Algra
Keyword(s):  
Neurodevelopmental Outcome ◽  
Neurological Dysfunction ◽  
Control Group ◽  
Double Blind ◽  
Term Infants ◽  
Neurological Condition ◽  
Beneficial Effects ◽  
Chain Pufa ◽  
Breast Fed ◽  
Long Chain

Long-chain PUFA (LCPUFA) supplementation of formula can have beneficial effects on neurodevelopmental outcome in early infancy, but uncertainty exists regarding effects after 6 months. The present study is the first to investigate whether consumption by term infants of formula containing LCPUFA for the first 2 months after birth improves neurological condition of these children at 9 years of age. A prospective, double-blind, randomised control study was performed in two groups of healthy term infants: a control group with standard formula (n 169) and a LCPUFA-supplemented group (LF; n 146). A breast-fed group (BF; n 159) served as a reference. At age 9 years, children were neurologically assessed according to Touwen, resulting in a Neurological Optimality Score and information on severity and type of minor neurological dysfunction (MND). Information on potential confounders was collected at enrolment and follow-up. Multivariate analyses were carried out to evaluate the effect of nutrition while adjusting for confounders. Attrition (28 %) was selective: drop-outs in the LF group were more often boys and had a significantly lower mental developmental index at 18 months. Neurological optimality and severity and type of MND at 9 years did not differ between the two formula groups. Children in the BF group showed significantly less often fine manipulative dysfunction than formula-fed children. In conclusion, LCPUFA supplementation of formula during the first 2 postnatal months in healthy term infants does not alter neurological function at school age. The study confirmed that breast-fed infants have a slightly better neurodevelopmental outcome than formula-fed infants.

scholarly journals Visual Function after Correction of Distance Refractive Error with Ready-made and Custom Spectacles: A Randomized Clinical Trial

Ophthalmology ◽  
2012 ◽  
Vol 119 (10) ◽  
pp. 2014-2020 ◽  
Author(s):  
Christopher J. Brady ◽  
Andrea C. Villanti ◽  
Monica Gandhi ◽  
David S. Friedman ◽  
Lisa Keay
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Refractive Error ◽  
Visual Function
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