Effects of megestrol acetate on weight gain, body composition, and pulmonary function in patients with cystic fibrosis

2002 ◽  
Vol 140 (4) ◽  
pp. 439-444 ◽  
Author(s):  
Valerie Eubanks ◽  
Nicki Koppersmith ◽  
Nancy Wooldridge ◽  
J.P. Clancy ◽  
Raymond Lyrene ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Body Composition ◽  
Weight Gain ◽  
Pulmonary Function ◽  
Megestrol Acetate

Association between body composition and pulmonary function in children and young people with cystic fibrosis

Nutrition ◽  
2018 ◽  
Vol 48 ◽  
pp. 73-76 ◽  
Author(s):  
Patrizia Calella ◽  
Giuliana Valerio ◽  
Matt Thomas ◽  
Helen McCabe ◽  
Jake Taylor ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Body Composition ◽  
Young People ◽  
Pulmonary Function ◽  
Children And Young People

Body-composition changes in patients who gain weight while receiving megestrol acetate.

1993 ◽  
Vol 11 (1) ◽  
pp. 152-154 ◽  
Author(s):  
C L Loprinzi ◽  
D J Schaid ◽  
A M Dose ◽  
N L Burnham ◽  
M D Jensen
Keyword(s):  
Body Composition ◽  
Weight Gain ◽  
Body Fluid ◽  
Dual Energy ◽  
Megestrol Acetate ◽  
Controlled Clinical Trials ◽  
Maximum Weight ◽  
X Ray ◽  
Composition Changes ◽  
Composition Measurements

PURPOSE Randomized placebo-controlled clinical trials have now established that megestrol acetate causes appetite stimulation and weight gain in patients with anorexia and/or cachexia. There is a paucity of available data to delineate the substance of this increased weight. PATIENTS AND METHODS Using dual-energy x-ray absorptiometry and tritiated body water methodologies, we performed body-composition measurements in 12 patients with advanced cancer before the institution of oral megestrol acetate (800 mg/d) and at subsequent 2-month intervals. RESULTS Seven of the 12 patients gained weight (2.1 to 16.5 kg) and had repeat body-composition measurements performed at the time of maximum weight gain. The vast majority of the gained weight was clearly from an increase in adipose tissue, while there was a suggestion that an increase in body fluid was responsible for a minority of the weight gain. CONCLUSION Megestrol acetate-induced weight gain is primarily the result of an increase in body mass.

scholarly journals Body Composition and Pulmonary Function in Cystic Fibrosis

2014 ◽  
Vol 2 ◽  
Author(s):  
Saba Sheikh ◽  
Babette S. Zemel ◽  
Virginia A. Stallings ◽  
Ronald C. Rubenstein ◽  
Andrea Kelly
Keyword(s):  
Cystic Fibrosis ◽  
Body Composition ◽  
Pulmonary Function

Pulmonary Function, Body Composition, and Protein Catabolism in Adults with Cystic Fibrosis

2002 ◽  
Vol 165 (4) ◽  
pp. 495-500 ◽  
Author(s):  
ALINA A. IONESCU ◽  
LISETTE S. NIXON ◽  
STEPHEN LUZIO ◽  
VANESSA LEWIS-JENKINS ◽  
WILLIAM D. EVANS ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Body Composition ◽  
Pulmonary Function ◽  
Protein Catabolism
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