The Preterm Prediction Study: Sequential cervical length and fetal fibronectin testing for the prediction of spontaneous preterm birth

2000 ◽  
Vol 182 (3) ◽  
pp. 636-643 ◽  
Author(s):  
Robert L. Goldenberg ◽  
Jay D. Iams ◽  
Anita Das ◽  
Brian M. Mercer ◽  
Paul J. Meis ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Cervical Length ◽  
Spontaneous Preterm Birth ◽  
Fetal Fibronectin

Prediction of spontaneous preterm birth in asymptomatic twin pregnancies with the use of combined fetal fibronectin and cervical length

2009 ◽  
Vol 201 (3) ◽  
pp. 313.e1-313.e5 ◽  
Author(s):  
Nathan S. Fox ◽  
Daniel H. Saltzman ◽  
Chad K. Klauser ◽  
Danielle Peress ◽  
Christina V. Gutierrez ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Cervical Length ◽  
Spontaneous Preterm Birth ◽  
Fetal Fibronectin ◽  
Twin Pregnancies

α and β-defensins and bacterial vaginosis as preterm birth predictors. A systematic review and meta-analysis.

2020 ◽  
Vol 2020 (4) ◽  
pp. 1-13
Author(s):  
Mariel Castillo-López ◽  
Keyword(s):  
Preterm Birth ◽  
Early Identification ◽  
Meta Analysis ◽  
Cervical Length ◽  
Premature Delivery ◽  
Spontaneous Preterm Birth ◽  
Fetal Fibronectin ◽  
Potential Damage ◽  
Type Of Delivery ◽  
Children Under 5

Preterm birth is an entity with potential damage to the newborn and it is the leading cause of mortality in children under 5 years old. Even though research on this topic has been increasing in the last decade, it has not reflected in a reduction in the incidence of this problem. Nowadays, raised cervical-vaginal fetal fibronectin concentration and short cervical length are considered the only predictors of spontaneous preterm birth [1], and given the adverse and severe consequences of preterm birth, the early identification of women with a higher risk of presenting this type of delivery is crucial for pregnancy care. Several studies have tried to find new inflammation markers that may allow the early identification of pregnant women at high risk of premature delivery, because as on many diseases, inflammatory mediators play a role on the pathophysiology of this entity. This literature review aims to discuss recent findings regarding to the association between the innate immune response, specifically β-defensins with preterm birth.

Correlation of cervical length, fetal fibronectin, phIGFBP-1, and cytokines in spontaneous preterm birth up to 14 days from sampling

2015 ◽  
Vol 43 (5) ◽  
Author(s):  
Marija Hadži-Lega ◽  
Ana Daneva Markova ◽  
Milan Stefanovic ◽  
Mile Tanturovski
Keyword(s):  
Preterm Birth ◽  
Preterm Delivery ◽  
Preterm Labor ◽  
Cervical Length ◽  
Outcome Variable ◽  
Spontaneous Preterm Birth ◽  
Fetal Fibronectin ◽  
Tnf Α ◽  
Vaginal Swabs ◽  
The Relationship

AbstractThe aim of this study was to determine the relationship between sonographic cervical length, fetal fibronectin (fFN), phIGFBP-1 (actim partus test), cytokines (IL-6, IL-2R, and TNF-α), and spontaneous preterm birth (SPTB) up to 14 days from sampling.Fifty-eight patients were recruited in a period of 6 months from September 2013 until March 2014 with symptoms or complaints suggestive of preterm labor. Consenting women were treated according to usual hospital protocol, with addition of vaginal swabs taken for fetal fibronectin, phIGFBP-1 (actim partus test) and cervical IL6, IL2R, and TNF-α. The outcome variable was occurrence of preterm delivery within 14 days from the day of hospital admission.Thirty-six patients (62.07%) were delivered within 14 days from admission. Our results indicated that the cervical length significantly inversely correlates with the concentration of IL-6 in the CVF (Spearman’s coefficient R=–0.382, P<0.05). Cervical length also correlated with a positive phIGFBP-1 test, i.e., patients with a positive test had an average cervical length of 18.5±4.63 mm, which is significantly lower than patients with a negative test –23.43±7.39 mm (P=0.003).The studied biochemical markers were only moderately successful in the prediction of preterm delivery.

scholarly journals OC103: Prediction of spontaneous preterm birth using ultrasound cervical length measurement and fetal fibronectin immunoassay

2008 ◽  
Vol 32 (3) ◽  
pp. 276-276
Author(s):  
S. Rosales-Ortiz ◽  
R. Cano-Carrillo ◽  
C. Santelices-LLanos ◽  
O. Moreno-Alvarez ◽  
J. A. B. Ayala-Mendez
Keyword(s):  
Preterm Birth ◽  
Cervical Length ◽  
Length Measurement ◽  
Spontaneous Preterm Birth ◽  
Fetal Fibronectin ◽  
Cervical Length Measurement
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