Birthweight and the future risk of cardiovascular disease: Does intrauterine malnutrition have a role in fetal programming?

2001 ◽  
Vol 138 (6) ◽  
pp. 378-386 ◽  
Author(s):  
A.Selçuk Adabağ
Keyword(s):  
Cardiovascular Disease ◽  
Fetal Programming ◽  
The Future ◽  
Future Risk ◽  
Intrauterine Malnutrition

scholarly journals Different impacts of metabolic profiles on future risk of cardiovascular disease between diabetes with and without established cardiovascular disease: the Japan diabetes complication and its prevention prospective study 7 (JDCP study 7)

2021 ◽  
Author(s):  
Mitsuyoshi Takahara ◽  
Naoto Katakami ◽  
Yasuaki Hayashino ◽  
Rimei Nishimura ◽  
Hiroaki Suzuki ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Primary Prevention ◽  
Density Lipoprotein ◽  
Lipoprotein Cholesterol ◽  
Metabolic Profiles ◽  
Cvd Risk ◽  
Cholesterol Levels ◽  
The Future ◽  
Patients With Diabetes ◽  
Future Risk

Abstract Aims Most risk calculators that predict future cardiovascular disease (CVD) by baseline profiles are originally developed for primary prevention, but some studies applied the calculators to secondary prevention. We compared the impact of baseline profiles on the future CVD risk between patients with diabetes with and without a CVD history. Methods We analyzed a multicenter prospective cohort of 6338 Japanese patients with diabetes aged 40–74 years, including those with (n = 634) and without a CVD history (n = 5704). The future risk of CVD was investigated using the competing risk model, with adjustment for non-cardiovascular mortality. Results During the median follow-up of 6.9 years, 413 CVD events were observed. The 8-year cumulative incidence rates of CVD were 21.5% and 7.2% in patients with and without a CVD history, respectively. A higher systolic blood pressure and lower high-density lipoprotein cholesterol levels were independently associated with a future CVD risk in patients without a CVD history (both P < 0.05), whereas they were not associated in those with a CVD history. The P values for interaction were 0.040 and 0.005, respectively. The male sex, an older age, a longer duration of diabetes, higher hemoglobin A1c levels, and higher low-density lipoprotein cholesterol levels were common independent risk factors regardless of CVD history (all P < 0.05). Conclusions The prognostic impact of metabolic profiles on CVD risk would not be identical between patients with and without a CVD history, suggesting that it might be inappropriate to apply CVD risk calculators developed for primary prevention to patients with a CVD history.

scholarly journals Is hyperfiltration associated with the future risk of developing diabetic nephropathy? A meta-analysis

Diabetologia ◽  
2009 ◽  
Vol 52 (4) ◽  
pp. 691-697 ◽  
Author(s):  
G. M. Magee ◽  
R. W. Bilous ◽  
C. R. Cardwell ◽  
S. J. Hunter ◽  
F. Kee ◽  
...  
Keyword(s):  
Diabetic Nephropathy ◽  
Meta Analysis ◽  
The Future ◽  
Future Risk

scholarly journals Self-Fulfilling Risk Panics

2012 ◽  
Vol 102 (7) ◽  
pp. 3674-3700 ◽  
Author(s):  
Philippe Bacchetta ◽  
Cédric Tille ◽  
Eric van Wincoop
Keyword(s):  
Stochastic Process ◽  
Perceived Risk ◽  
Focal Point ◽  
Asset Price ◽  
Current Level ◽  
Price Risk ◽  
The Future ◽  
Future Risk ◽  
Negative Link

Recent crises have seen large spikes in asset price risk. We propose an explanation for such panics based on self-fulfilling shifts in beliefs about risk. A negative link between the current level and the future risk of an asset price leads to a circular relationship between the stochastic process of asset price risk and the price itself. Self-fulfilling shifts in perceived risk can be coordinated around a pure sunspot or around a macro fundamental. In a risk panic, a macro fundamental can be a focal point that affects both the magnitude of the panic and subsequent shifts in perceived risk.

scholarly journals Plasma retinol, β-carotene and vitamin E levels in relation to the future risk of breast cancer

1984 ◽  
Vol 49 (3) ◽  
pp. 321-324 ◽  
Author(s):  
N J Wald ◽  
J Boreham ◽  
J L Hayward ◽  
R D Bulbrook
Keyword(s):  
Breast Cancer ◽  
Vitamin E ◽  
The Future ◽  
Future Risk ◽  
Plasma Retinol ◽  
Β Carotene
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