Investigation of infection control practices and knowledge of hepatitis C among body-piercing practitioners

2003 ◽  
Vol 31 (4) ◽  
pp. 215-220 ◽  
Author(s):  
Margaret Hellard ◽  
Campbell Aitken ◽  
Andrew Mackintosh ◽  
Allison Ridge ◽  
Scott Bowden
Keyword(s):  
Hepatitis C ◽  
Infection Control ◽  
Body Piercing

Hepatitis C Virus Transmission in Hemodialysis Units Importance of Infection Control Practices and Aseptic Technique

2009 ◽  
Vol 30 (9) ◽  
pp. 900-903 ◽  
Author(s):  
Nicola D. Thompson ◽  
Ryan T. Novak ◽  
Deblina Datta ◽  
Susanne Cotter ◽  
Matthew J. Arduino ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Infection Control ◽  
Virus Transmission ◽  
Hcv Infection ◽  
Cross Contamination ◽  
Aseptic Technique ◽  
Hcv Transmission ◽  
Intravenous Medication ◽  
Hepatitis C Virus Transmission

We investigated 4 hepatitis C virus (HCV) infection outbreaks at hemodialysis units to identify practices associated with transmission. Apparent failures to follow recommended infection control precautions resulted in patient-to-patient HCV transmission, through cross-contamination of the environment or intravenous medication vials. Fastidious attention to aseptic technique and infection control precautions are essential to prevent HCV transmission.

INSIDE INDUSTRY

2016 ◽  
Vol 20 (09) ◽  
pp. 38-48
Keyword(s):  
Systematic Review ◽  
Hepatitis C ◽  
Disease Prevention ◽  
Infection Control ◽  
Proton Beam ◽  
Array Cgh ◽  
Proton Beam Therapy ◽  
World Congress ◽  
Cardiac Inflammation

Experts at World Congress of Internal Medicines Reinforce Importance of BETADINE® in Disease Prevention, Infection Control and Oral Mucositis Treatment. First Dengue Vaccination Program in the Americas Starts in Paraná State of Brazil. Agilent Technologies Array CGH Platform Assures Quality of Cancer Cell Lines Used in Biomedical Research. ARTES and Burnet Institute Join Forces to Develop Novel Hepatitis C Vaccine. Cardiac Imaging Reveals the Association Between Increased Prevalence of Coronary Issues Among Men with HIV and Higher Indications of Cardiac Inflammation. NCCS Awards Contract for Proton Beam Therapy System to Hitachi Asia Ltd. Hitachi is Selected by National Cancer Centre Singapore for Southeast Asia’s First Proton Beam Therapy System. FEI Introduces New Talos S/TEM for Life and Materials Sciences. Systematic Review of 58 Publications of Real-World Use of GARDASIL® Presented at AOGIN Congress.

scholarly journals Mechanisms of Methods for Hepatitis C Virus Inactivation

2014 ◽  
Vol 81 (5) ◽  
pp. 1616-1621 ◽  
Author(s):  
Stephanie Pfaender ◽  
Janine Brinkmann ◽  
Daniel Todt ◽  
Nina Riebesehl ◽  
Joerg Steinmann ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Infection Control ◽  
Viral Envelope ◽  
Enzyme Linked Immunosorbent Assay ◽  
Virus Inactivation ◽  
Protection Assay ◽  
Uv Treatment ◽  
Enveloped Viruses ◽  
Enveloped Virus

ABSTRACTVirus inactivation by chemical disinfectants is an important instrument for infection control in medical settings, but the mechanisms involved are poorly understood. In this study, we systematically investigated the effects of several antiviral treatments on hepatitis C virus (HCV) particles as model for enveloped viruses. Studies were performed with authentic cell culture-derived viruses, and the influence of chemical disinfectants, heat, and UV treatment on HCV was analyzed by the determination of infectious particles in a limiting-dilution assay, by quantitative reverse transcription-PCR, by core enzyme-linked immunosorbent assay, and by proteolytic protection assay. All different inactivation methods resulted in a loss of HCV infectivity by targeting different parts of the virus particle. Alcohols such as ethanol and 2-propanol did not affect the viral RNA genome integrity but disrupted the viral envelope membrane in a capsid protection assay. Heat and UV treatment of HCV particles resulted in direct damage of the viral genome since transfection of viral particle-associated RNA into permissive cells did not initiate RNA replication. In addition, heat incubation at 80°C disrupted the HCV envelope, rendering the viral capsid susceptible to proteolytic digest. This study demonstrated the molecular processes of viral inactivation of an enveloped virus and should facilitate the development of effective disinfection strategies in infection control not only against HCV but also against other enveloped viruses.

scholarly journals Infection control of hepatitis C in Dutch dialysis centres

1998 ◽  
Vol 13 (12) ◽  
pp. 3037-3040 ◽  
Author(s):  
P. Schneeberger ◽  
N. Toonen ◽  
I. Keur ◽  
H. van Hamersvelt
Keyword(s):  
Hepatitis C ◽  
Infection Control

scholarly journals Hepatitis C Virus Transmission at a Long-Term Care Facility (LTCF) Providing Hemodialysis Services—Georgia, United States, 2019

2020 ◽  
Vol 41 (S1) ◽  
pp. s248-s249
Author(s):  
JoAnna Wagner ◽  
Ami Gandhi ◽  
Bill Johnson ◽  
Nicole Gualandi ◽  
Danae Bixler ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Infection Control ◽  
Long Term Care ◽  
Care Facility ◽  
Multiple Infection ◽  
Term Care ◽  
Hcv Genotype ◽  
Hcv Transmission

Background: Hepatitis C virus (HCV) transmission at outpatient hemodialysis clinics is well documented, but little is known about HCV transmission risks in long-term care facilities (LTCFs) providing hemodialysis services. LTCFs can provide onsite hemodialysis for residents by contracting with a licensed hemodialysis clinic to either provide its staff to the LTCF or to train LTCF staff as caregivers. In August 2019, the Georgia Department of Public Health (DPH) was notified about an HCV seroconversion in patient A at a LTCF providing onsite hemodialysis. Methods: Three residents (including patient A) were receiving hemodialysis at the LTCF in August 2019; patients B and C had chronic HCV infection upon admission. Records were reviewed for medical history, behavioral risk factors, and healthcare exposures. We conducted onsite infection control assessments and interviewed staff. Serum specimens were collected for all 3 patients in August 2019 and HCV tested for genetic similarity using Global Hepatitis Outbreak Surveillance Technology (GHOST). Results: The facility reported initiating onsite hemodialysis in November 2018; facility staff were trained by a dialysis provider. Patient A, admitted in September 2018, was anti-HCV negative in June 2019 and both anti-HCV and HCV RNA positive in July 2019. Patient B was admitted in December 2018, discharged for 1 month in May 2019, and then readmitted. Patients A and B reported previous injection drug use, and they were not observed by staff to use during their stay and had limited mobility. Patient A was wheelchair confined and B was bed confined. Patient C was admitted in May 2019. HCV samples from patients A and B both had HCV genotype 1b and demonstrated 100% genetic relatedness, indicating that patient B was the likely source. Patient C had HCV genotype 1a. Hemodialysis was provided to residents simultaneously in a converted resident room with 4 hemodialysis stations, and the LTCF operated 2 shifts, 3 times per week. We observed multiple infection control gaps, such as preparation of IV medications and inadequate disinfection in the shared dialysis treatment area. Recommendations addressing gaps were issued, and a follow-up site visit was conducted to validate implementation. With the exception of May 2019, patients A and B received hemodialysis on the same shift and days from December 2018 to September 2019. Conclusions: Phylogenetic and epidemiological results indicate HCV transmission likely occurred during hemodialysis services provided by the LTCF. As the provision of dialysis expands to nontraditional settings such as LTCFs, it is essential that proper infection control procedures and oversight are in place.Funding: NoneDisclosures: None

Seroprevalence of Hepatitis B, Hepatitis C, and Human Immunodeficiency Viruses in End-Stage Renal Disease Patients, Southern Iran

2020 ◽  
Vol 16 (1) ◽  
pp. 44-51
Author(s):  
Nahid T. Movaghar ◽  
Saber Mojarrad ◽  
Hadi R. Shahraki ◽  
Mohammadreza Nazari ◽  
Mahtab Hadadi ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Hepatitis B ◽  
Infection Control ◽  
Hiv Infection ◽  
Demographic Data ◽  
Control Measures ◽  
Fars Province ◽  
Cross Sectional ◽  
Strict Adherence ◽  
Southern Iran

Background: Hemodialysis [HD] patients are more prone to blood-borne viruses, such as hepatitis B virus [HBV], hepatitis C virus [HCV], and, to a lesser extent, Human Immunodeficiency Virus [HIV]. Chronic HBV and HCV infections are associated with liver cirrhosis, hepatocellular carcinoma, and early graft failure after kidney transplantation. As there was no recent information, this study aimed to evaluate the prevalence of HBV, HCV, and HIV infection in HD patients in Fars province, southern Iran. This could help health policymakers to run more effective infection control practices for reducing such blood-borne virus infections, if necessary. Methods: This cross-sectional study was performed on 906 HD patients in Fars province, southern Iran. A total of 906 blood samples were obtained from patients and diagnostic tests of HBV, HCV, and HIV were done. Demographic data and some other information, such as duration of dialysis, were extracted from the patients’ medical records. Data were analyzed in SPSS, version 18. Results: Out of the patients enrolled in the study, 547 [60.4%] were male and 359 [39.6%] female. The mean ± SD age of the patients was 58.0 ± 15.8 years. The prevalence of HBV, HCV, and HIV infection was 0.88%, 0.55% and 0.44%, respectively. HIV-infected subjects were significantly younger than the HIV-negative group [P <0.017]. Conclusion: It seems that Fars is among the provinces with low HBV and HCV prevalence in HD patients in comparison to other provinces of Iran. On the other hand, HIV prevalence here is higher than other provincial studies. Strict adherence to preventive infection control measures is recommended in HD centers.

Sign in / Sign up

Export Citation Format

Share Document