Study of the iron distribution profile and the influence of annealing on the structure implanted in silicon

2021 ◽  
Author(s):  
B. E. Egamberdiev ◽  
A. S. Mallayev ◽  
Sh. A. Sayfulloev ◽  
M. I. Rahmatov
Keyword(s):  
Distribution Profile ◽  
Iron Distribution

scholarly journals Regulation of intracellular iron distribution in K562 human erythroleukemia cells.

1986 ◽  
Vol 261 (10) ◽  
pp. 4587-4593 ◽  
Author(s):  
E Mattia ◽  
D Josic ◽  
G Ashwell ◽  
R Klausner ◽  
J van Renswoude
Keyword(s):  
Intracellular Iron ◽  
Iron Distribution ◽  
Erythroleukemia Cells

scholarly journals PSMA-D4 Radioligand for Targeted Therapy of Prostate Cancer: Synthesis, Characteristics and Preliminary Assessment of Biological Properties

2021 ◽  
Vol 22 (5) ◽  
pp. 2731
Author(s):  
Piotr Garnuszek ◽  
Urszula Karczmarczyk ◽  
Michał Maurin ◽  
Arkadiusz Sikora ◽  
Jolanta Zaborniak ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Targeted Therapy ◽  
Ex Vivo ◽  
Specific Binding ◽  
Biological Evaluation ◽  
In Vitro Assays ◽  
The Novel ◽  
Distribution Profile ◽  
System L

A new PSMA ligand (PSMA-D4) containing the Glu-CO-Lys pharmacophore connected with a new linker system (L-Trp-4-Amc) and chelator DOTA was developed for radiolabeling with therapeutic radionuclides. Herein we describe the synthesis, radiolabeling, and preliminary biological evaluation of the novel PSMA-D4 ligand. Synthesized PSMA-D4 was characterized using TOF-ESI-MS, NMR, and HPLC methods. The novel compound was subject to molecular modeling with GCP-II to compare its binding mode to analogous reference compounds. The radiolabeling efficiency of PSMA-D4 with 177Lu, 90Y, 47Sc, and 225Ac was chromatographically tested. In vitro studies were carried out in PSMA-positive LNCaP tumor cells membranes. The ex vivo tissue distribution profile of the radioligands and Cerenkov luminescence imaging (CLI) was studied in LNCaP tumor-bearing mice. PSMA-D4 was synthesized in 24% yield and purity >97%. The radio complexes were obtained with high yields (>97%) and molar activity ranging from 0.11 to 17.2 GBq mcmol−1, depending on the radionuclide. In vitro assays confirmed high specific binding and affinity for all radiocomplexes. Biodistribution and imaging studies revealed high accumulation in LNCaP tumor xenografts and rapid clearance of radiocomplexes from blood and non-target tissues. These render PSMA-D4 a promising ligand for targeted therapy of prostate cancer (PCa) metastases.

The iron-chelate transporter OsYSL9 plays a role in iron distribution in developing rice grains

2017 ◽  
Vol 95 (4-5) ◽  
pp. 375-387 ◽  
Author(s):  
Takeshi Senoura ◽  
Emi Sakashita ◽  
Takanori Kobayashi ◽  
Michiko Takahashi ◽  
May Sann Aung ◽  
...  
Keyword(s):  
Iron Chelate ◽  
Iron Distribution ◽  
Rice Grains

Effects of morphology of buffer layers on ZnO/sapphire heteroepitaxial growth by RF magnetron sputtering

2015 ◽  
Vol 1741 ◽  
Author(s):  
Tomoaki Ide ◽  
Koichi Matsushima ◽  
Ryota Shimizu ◽  
Daisuke Yamashita ◽  
Hynwoong Seo ◽  
...  
Keyword(s):  
Rf Magnetron Sputtering ◽  
Buffer Layers ◽  
Crystal Nucleation ◽  
Zno Films ◽  
Growth Stages ◽  
Initial Growth ◽  
Height Distribution ◽  
Heteroepitaxial Growth ◽  
Distribution Profile

ABSTRACTEffects of surface morphology of buffer layers on ZnO/sapphire heteroepitaxial growth have been investigated by means of “nitrogen mediated crystallization (NMC) method”, where the crystal nucleation and growth are controlled by absorbed nitrogen atoms. We found a strong correlation between the height distribution profile of NMC-ZnO buffer layers and the crystal quality of ZnO films. On the buffer layer with a sharp peak in height distribution, a single-crystalline ZnO film with atomically-flat surface was grown. Our results indicate that homogeneous and high-density nucleation at the initial growth stages is critical in heteroepitaxy of ZnO on lattice mismatched substrates.

scholarly journals Mortality in traffic accidents with older adults in Colombia

2017 ◽  
Vol 51 (0) ◽  
Author(s):  
Angela Maria Segura Cardona ◽  
Doris Cardona Arango ◽  
Dedsy Yajaira Berbesí Fernández ◽  
Alejandra Agudelo Martínez
Keyword(s):  
Older Adults ◽  
Traffic Accident ◽  
Traffic Accidents ◽  
Adult Population ◽  
Years Of Life Lost ◽  
Distribution Profile ◽  
Safety Measures ◽  
Risk Of Death ◽  
Increased Risk ◽  
Age Range

ABSTRACT OBJECTIVE To analyze the traffic accident mortality in the Colombian older adults during the 1998-2012 period and show the loss of productive years and mortality from this cause. METHODS Quantitative study of the trend analysis of deaths in Colombia in traffic accidents, from 1998 to 2012, according to death records and population projected by the Colombian National Administrative Department of Statistics. Frequency distribution profile of the deceased, death rates per hundred thousand inhabitants, potential years of life lost and calculation of excess mortality by age in the over 60 were made. RESULTS In the study period 100,758 deaths occurred in traffic accidents, 6,717 annual average, of which 18.5% occurred in people aged 60 years and over. The predominated deaths were men; the risk of dying was 32.15 per hundred thousand people in this age range, with double risk of dying those under 60 years. CONCLUSIONS The young population has a higher proportion of deaths, but those over 60 years are at increased risk of death, leading to the need to turn our gaze to the improvement of road infrastructure and standards, to educate the population in self-care and compliance with safety measures and prepare society for an ever more adult population, more numerous and more prone to take risks.

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