Research on optimized structure of a 220-GHz extended interaction oscillator

2021 ◽  
Vol 28 (9) ◽  
pp. 093108
Author(s):  
Jielong Li ◽  
Zhenhua Wu ◽  
Min Hu ◽  
Renbin Zhong ◽  
Kaichun Zhang ◽  
...  
Keyword(s):  
Extended Interaction

scholarly journals Extended Interactions between HIV-1 Viral RNA and tRNALys3 Are Important to Maintain Viral RNA Integrity

2020 ◽  
Vol 22 (1) ◽  
pp. 58
Author(s):  
Thomas Gremminger ◽  
Zhenwei Song ◽  
Juan Ji ◽  
Avery Foster ◽  
Kexin Weng ◽  
...  
Keyword(s):  
Reverse Transcription ◽  
Potential Interaction ◽  
Viral Rna ◽  
Primer Binding Site ◽  
Rna Integrity ◽  
Immunodeficiency Virus ◽  
Infected Cells ◽  
Extended Interaction ◽  
Hiv 1

The reverse transcription of the human immunodeficiency virus 1 (HIV-1) initiates upon annealing of the 3′-18-nt of tRNALys3 onto the primer binding site (PBS) in viral RNA (vRNA). Additional intermolecular interactions between tRNALys3 and vRNA have been reported, but their functions remain unclear. Here, we show that abolishing one potential interaction, the A-rich loop: tRNALys3 anticodon interaction in the HIV-1 MAL strain, led to a decrease in viral infectivity and reduced the synthesis of reverse transcription products in newly infected cells. In vitro biophysical and functional experiments revealed that disruption of the extended interaction resulted in an increased affinity for reverse transcriptase (RT) and enhanced primer extension efficiency. In the absence of deoxyribose nucleoside triphosphates (dNTPs), vRNA was degraded by the RNaseH activity of RT, and the degradation rate was slower in the complex with the extended interaction. Consistently, the loss of vRNA integrity was detected in virions containing A-rich loop mutations. Similar results were observed in the HIV-1 NL4.3 strain, and we show that the nucleocapsid (NC) protein is necessary to promote the extended vRNA: tRNALys3 interactions in vitro. In summary, our data revealed that the additional intermolecular interaction between tRNALys3 and vRNA is likely a conserved mechanism among various HIV-1 strains and protects the vRNA from RNaseH degradation in mature virions.

Feasibility study of a THz sheet beam extended interaction oscillator

2018 ◽  
Author(s):  
Che Xu ◽  
Bin Wang ◽  
Yong Yin ◽  
Liangjie Bi ◽  
Hailong Li ◽  
...  
Keyword(s):  
Feasibility Study ◽  
Extended Interaction

scholarly journals Improvement of the extended interaction by modifying the monopole field

2001 ◽  
Vol 688 (3-4) ◽  
pp. 765-788 ◽  
Author(s):  
M. Hasegawa ◽  
K. Kaneko ◽  
S. Tazaki
Keyword(s):  
Extended Interaction

scholarly journals Structural elastic and thermal properties of SrxCd1−x O mixed compounds — a theoretical approach

2014 ◽  
Vol 32 (3) ◽  
pp. 350-357
Author(s):  
Purvee Bhardwaj
Keyword(s):  
Phase Transition ◽  
Vibrational Energy ◽  
Zero Point ◽  
Study Phase ◽  
Energy Effect ◽  
Phase Transition Pressure ◽  
Vegard’S Law ◽  
Extended Interaction ◽  
Experimental Values ◽  
Good Agreement

AbstractIn the present paper, the structural and mechanical properties of alkaline earth oxides mixed compound SrxCd1−x O (0 ≤ x ≤ 1) under high pressure have been reported. An extended interaction potential (EIP) model, including the zero point vibrational energy effect, has been developed for this study. Phase transition pressures are associated with a sudden collapse in volume. Phase transition pressure and associated volume collapses [ΔV (Pt)/V(0)] calculated from this approach are in good agreement with the experimental values for the parent compounds (x = 0 and x = 1). The results for the mixed crystal counterparts are also in fair agreement with experimental data generated from the application of Vegard’s law to the data for the parent compounds.

Simulation study of D-band extended interaction klystron amplifier

2021 ◽  
Author(s):  
Dongrui Chen ◽  
Xiaotao Xu ◽  
Xuesong Yuan ◽  
Bin Wang ◽  
Hailong Li ◽  
...  
Keyword(s):  
Simulation Study ◽  
Extended Interaction

Thermal Cavity Calculation of 38GHz Extended Interaction Oscillator

2021 ◽  
Author(s):  
Jie Qing ◽  
Xinjian Niu ◽  
Tianzhong Zhang ◽  
Yinghui Liu
Keyword(s):  
Extended Interaction
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