scholarly journals Synthesis of new vanillin derivatives from natural eugenol

2021 ◽  
Author(s):  
Reni Rahayu ◽  
Muhammad A. Aziz ◽  
Mohammad Holil ◽  
Mardi Santoso
Keyword(s):  
Vanillin Derivatives

scholarly journals Novel vanillin derivatives: Synthesis, anti-oxidant, DNA and cellular protection properties

2018 ◽  
Vol 143 ◽  
pp. 745-754 ◽  
Author(s):  
Matteo Scipioni ◽  
Graeme Kay ◽  
Ian Megson ◽  
Paul Kong Thoo Lin
Keyword(s):  
Cellular Protection ◽  
Anti Oxidant ◽  
Vanillin Derivatives

scholarly journals Vanillin derivatives affecting the central and peripheral nervous system

2018 ◽  
Author(s):  
Mariia Nesterkina ◽  
Elena Fedorova ◽  
Yuriy Boyko ◽  
Iryna Kravchenko
Keyword(s):  
Nervous System ◽  
Peripheral Nervous System ◽  
Vanillin Derivatives

scholarly journals Removal of Pb(II) Metal Ions from Aqueous Solutions Using Chitosan-Vanillin Derivatives of Chelating Polymers

2019 ◽  
Vol 28 (3) ◽  
pp. 1523-1534 ◽  
Author(s):  
Fadi Alakhras ◽  
Hanin Al-Shahrani ◽  
Eman Al-Abbad ◽  
Fuad Al-Rimawi ◽  
Noureddine Ouerfelli
Keyword(s):  
Aqueous Solutions ◽  
Metal Ions ◽  
Vanillin Derivatives ◽  
Derivatives Of ◽  
Chelating Polymers

ChemInform Abstract: Vanillin Derivatives Showing Various Biological Activities

ChemInform ◽  
2012 ◽  
Vol 43 (28) ◽  
pp. no-no
Author(s):  
Ravendra Kumar ◽  
P. K. Sharma ◽  
Prem Shanker Mishra
Keyword(s):  
Biological Activities ◽  
Vanillin Derivatives

scholarly journals Pharmacophore modelling of vanillin derivatives, favipiravir, chloroquine, hydroxychloroquine, monolaurin and tetrodotoxin as MPro inhibitors of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)

2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Woon Yi Law ◽  
Mohd Razip Asaruddin ◽  
Showkat Ahamd Bhawani ◽  
Samsur Mohamad
Keyword(s):  
Hydrogen Bond ◽  
Pharmacophore Model ◽  
Significant Activity ◽  
Inhibition Activity ◽  
Pharmacophore Modelling ◽  
Common Features ◽  
Complex Interactions ◽  
Test Sets ◽  
Vanillin Derivatives ◽  
Modelling Approach

Abstract Objectives The aim of this study was to use Ligand-based pharmacophore modelling approach for four established antiviral drugs, namely remdesivir, lopinavir, ritonavir and hydroxychloroquine for COVID-19 inhibitors as training sets. In this study Twenty vanillin derivatives together with monolaurin and tetrodotoxin were used as test sets to evaluate as potential SARS-CoV-2 inhibitors. The Structure-based pharmacophore modelling approach was also performed using 5RE6, 5REX and 5RFZ in order to analyse the binding site and ligand–protein complex interactions. Results The pharmacophore modelling mode of 5RE6 displayed two Hydrogen Bond Acceptors (HBA) and one Hydrophobic (HY) interaction. Besides, the pharmacophore model of 5REX showed two HBA and two HY interactions. Finally, the pharmacophore model of 5RFZ showed three HBA and one HY interaction. Based on ligand-based approach, 20 Schiff-based vanillin derivatives, showed strong MPro inhibition activity. This was due to their good alignment and common features to PDB-5RE6. Similarly, monolaurin and tetrodotoxin displayed some significant activity against SARS-CoV-2. From structure-based approach, vanillin derivatives (1) to (12) displayed some potent MPro inhibition against SARS-CoV-2. Favipiravir, chloroquine and hydroxychloroquine also showed some significant MPro inhibition.

scholarly journals Coenzyme A‐Conjugated Cinnamic Acids – Enzymatic Synthesis of a CoA‐Ester Library and Application in Biocatalytic Cascades to Vanillin Derivatives

2019 ◽  
Vol 361 (23) ◽  
pp. 5346-5350 ◽  
Author(s):  
Martin Dippe ◽  
Anne‐Katrin Bauer ◽  
Andrea Porzel ◽  
Evelyn Funke ◽  
Anna O. Müller ◽  
...  
Keyword(s):  
Enzymatic Synthesis ◽  
Coenzyme A ◽  
Cinnamic Acids ◽  
Vanillin Derivatives
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