scholarly journals Cisplatin uptake and release in pH sensitive zeolitic imidazole frameworks

2021 ◽  
Vol 154 (24) ◽  
pp. 244703
Author(s):  
Megan J. Thompson ◽  
Stephen A. Wells ◽  
Tina Düren
Keyword(s):  
Ph Sensitive ◽  
Zeolitic Imidazole Frameworks ◽  
Uptake And Release

Loading and release of fluorescent oligoarginine peptides into/from pH-responsive anionic supramolecular nanoparticles

2016 ◽  
Vol 4 (22) ◽  
pp. 4025-4032 ◽  
Author(s):  
Laura Graña-Suárez ◽  
Willem Verboom ◽  
Tessa Buckle ◽  
Mark Rood ◽  
Fijs W. B. van Leeuwen ◽  
...  
Keyword(s):  
Ph Sensitive ◽  
Ph Responsive ◽  
Supramolecular Nanoparticles ◽  
Uptake And Release

The uptake and release of fluorescent oligoarginines was studied into/from a pH-sensitive system based on negatively charged fluorescent supramolecular nanoparticles.

Uptake and release of budesonide from mucoadhesive, pH-sensitive copolymers and their application to nasal delivery

1999 ◽  
Vol 61 (3) ◽  
pp. 329-335 ◽  
Author(s):  
Kouji Nakamura ◽  
Yoshie Maitani ◽  
Anthony M Lowman ◽  
Kozo Takayama ◽  
Nicholas A Peppas ◽  
...  
Keyword(s):  
Ph Sensitive ◽  
Nasal Delivery ◽  
Uptake And Release

MgO Nanoparticles for Effective Uptake and Release of Doxorubicin Drug: pH Sensitive Controlled Drug Release

2016 ◽  
Vol 16 (9) ◽  
pp. 9421-9431 ◽  
Author(s):  
Thirunavukkarasu Somanathan ◽  
Vemula Mohana Krishna ◽  
Velautham Saravanan ◽  
Raju Kumar ◽  
Randhir Kumar
Keyword(s):  
Drug Release ◽  
Controlled Drug Release ◽  
Ph Sensitive ◽  
Mgo Nanoparticles ◽  
Uptake And Release

Effects of Halothane on Platelet Function

1980 ◽  
Vol 44 (03) ◽  
pp. 143-145 ◽  
Author(s):  
J Dalsgaard-Nielsen ◽  
J Gormsen
Keyword(s):  
Platelet Aggregation ◽  
Platelet Function ◽  
Platelet Rich Plasma ◽  
Human Platelets ◽  
Halothane Anaesthesia ◽  
Inhibition Of Platelet Aggregation ◽  
Transient Impairment ◽  
High Concentrations ◽  
Uptake And Release ◽  
Platelet Functions

SummaryHuman platelets in platelet rich plasma (PRP) incubated at 37° C with 0.3–2% halothane for 5–10 min lost the ability to aggregate with ADP, epinephrine and collagen.At the same time uptake and release of 14C-serotonin was inhibited. When halothane supply was removed, platelet functions rapidly returned to normal. However, after high concentrations of halothane, the inhibition of platelet aggregation was irreversible or only partially reversible.The results suggest that halothane anaesthesia produces a transient impairment of platelet function.

A Mechanism for Reversibly Pausing a Self-Immolation Cascade in Response to pH Changes

2019 ◽  
Author(s):  
Derrick Roberts ◽  
Ben S. Pilgrim ◽  
Tristan Dell ◽  
Molly Stevens
Keyword(s):  
Local Environment ◽  
Chemical Signals ◽  
Ph Sensitive ◽  
First Report ◽  
Ph Changes ◽  
Self Immolation

We describe the first report of a self-immolation cascade that can be reversibly paused and reactivated in response to pH changes. This system employs a triazole-based self-immolative linker, which expresses a pH-sensitive intermediate during its elimination sequence. This allows the system to respond to pH cues within its local environment, thus establishing a new way to gate self-immolative release using fluctuating or transient chemical signals.<br>

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