scholarly journals Controllability of voltage- and calcium-driven cardiac alternans in a map model

2021 ◽  
Vol 31 (2) ◽  
pp. 023139
Author(s):  
Laura M. Muñoz ◽  
Mark O. Ampofo ◽  
Elizabeth M. Cherry
Keyword(s):  
Heart Rhythm ◽  
2021 ◽  
Vol 18 (8) ◽  
pp. S105-S106
Author(s):  
Kanchan Kulkarni ◽  
Nestor Pallares-Lupon ◽  
Virginie Loyer ◽  
Stephane Bloquet ◽  
Dounia El Hamrani ◽  
...  

2008 ◽  
Vol 3 (4) ◽  
pp. 041004 ◽  
Author(s):  
Xiaopeng Zhao ◽  
David G. Schaeffer ◽  
Carolyn M. Berger ◽  
Wanda Krassowska ◽  
Daniel J. Gauthier

1997 ◽  
Vol 79 (24) ◽  
pp. 4938-4938 ◽  
Author(s):  
Daniel J. Gauthier ◽  
Joshua E. S. Socolar

2020 ◽  
Vol 30 (8) ◽  
pp. 083123
Author(s):  
Sanket Thakare ◽  
Joseph Mathew ◽  
Sharon Zlochiver ◽  
Xiaopeng Zhao ◽  
Elena G. Tolkacheva

2004 ◽  
Vol 94 (5) ◽  
pp. 570-572 ◽  
Author(s):  
Karin R. Sipido
Keyword(s):  

2019 ◽  
Vol 4 (1) ◽  
Author(s):  
Yi Ming Lai ◽  
Joshua Veasy ◽  
Stephen Coombes ◽  
Rüdiger Thul

Abstract During a single heartbeat, muscle cells in the heart contract and relax. Under healthy conditions, the behaviour of these muscle cells is almost identical from one beat to the next. However, this regular rhythm can be disturbed giving rise to a variety of cardiac arrhythmias including cardiac alternans. Here, we focus on so-called microscopic calcium alternans and show how their complex spatial patterns can be understood with the help of the master stability function. Our work makes use of the fact that cardiac muscle cells can be conceptualised as a network of networks, and that calcium alternans correspond to an instability of the synchronous network state. In particular, we demonstrate how small changes in the coupling strength between network nodes can give rise to drastically different activity patterns in the network.


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