Targeting improved reproducibility in surface-enhanced Raman spectroscopy with planar substrates using 3D printed alignment holders

2021 ◽  
Vol 92 (4) ◽  
pp. 043102
Author(s):  
Buddini Iroshika Karawdeniya ◽  
Robert B. Chevalier ◽  
Y. M. Nuwan D. Y. Bandara ◽  
Jason R. Dwyer
Keyword(s):  
Raman Spectroscopy ◽  
Surface Enhanced Raman Spectroscopy ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
3D Printed ◽  
Planar Substrates

scholarly journals 3D-Printed Peptide-Hydrogel Nanoparticle Composites for Surface-Enhanced Raman Spectroscopy Sensing

2019 ◽  
Vol 2 (8) ◽  
pp. 5029-5034 ◽  
Author(s):  
Sawsan Almohammed ◽  
Maha Alruwaili ◽  
Emmanuel G. Reynaud ◽  
Gareth Redmond ◽  
James H. Rice ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Surface Enhanced Raman Spectroscopy ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
3D Printed ◽  
Nanoparticle Composites ◽  
Peptide Hydrogel

Highly sensitive and uniform surface-enhanced Raman spectroscopy from grating-integrated plasmonic nanograss

2016 ◽  
Vol 1 (4) ◽  
pp. 290-297 ◽  
Author(s):  
Yang Shen ◽  
Xizhe Cheng ◽  
Guozhen Li ◽  
Qiangzhong Zhu ◽  
Zhenguo Chi ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Surface Enhanced Raman Spectroscopy ◽  
Signal Enhancement ◽  
Highly Sensitive ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Planar Substrates ◽  
Sers Sensing

We developed a SERS sensing strategy based on grating-integrated substrates with 10-fold signal enhancement compared to the planar substrates.

Bacterial detection and differentiation via direct volatile organic compound sensing with surface enhanced Raman spectroscopy

2017 ◽  
Author(s):  
Caitlin S. DeJong ◽  
David I. Wang ◽  
Aleksandr Polyakov ◽  
Anita Rogacs ◽  
Steven J. Simske ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Bacterial Infections ◽  
Direct Detection ◽  
Point Of Care ◽  
Surface Enhanced Raman Spectroscopy ◽  
E Coli ◽  
Recent Emergence ◽  
Surface Enhanced ◽  
Volatile Organic ◽  
Surface Enhanced Raman

Through the direct detection of bacterial volatile organic compounds (VOCs), via surface enhanced Raman spectroscopy (SERS), we report here a reconfigurable assay for the identification and monitoring of bacteria. We demonstrate differentiation between highly clinically relevant organisms: <i>Escherichia coli</i>, <i>Enterobacter cloacae</i>, and <i>Serratia marcescens</i>. This is the first differentiation of bacteria via SERS of bacterial VOC signatures. The assay also detected as few as 10 CFU/ml of <i>E. coli</i> in under 12 hrs, and detected <i>E. coli</i> from whole human blood and human urine in 16 hrs at clinically relevant concentrations of 10<sup>3</sup> CFU/ml and 10<sup>4</sup> CFU/ml, respectively. In addition, the recent emergence of portable Raman spectrometers uniquely allows SERS to bring VOC detection to point-of-care settings for diagnosing bacterial infections.

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