Mechanism of surface freezing of alkanes

2020 ◽  
Vol 153 (22) ◽  
pp. 224501
Author(s):  
Viraj P. Modak ◽  
Barbara E. Wyslouzil ◽  
Sherwin J. Singer
Keyword(s):  
1998 ◽  
Vol 58 (5) ◽  
pp. 6086-6100 ◽  
Author(s):  
O. Gang ◽  
X. Z. Wu ◽  
B. M. Ocko ◽  
E. B. Sirota ◽  
M. Deutsch

2003 ◽  
Vol 68 (3) ◽  
Author(s):  
E. Sloutskin ◽  
X. Z. Wu ◽  
T. B. Peterson ◽  
O. Gang ◽  
B. M. Ocko ◽  
...  

1982 ◽  
Vol 2 (2) ◽  
pp. 229-239 ◽  
Author(s):  
G. Benzi ◽  
E. Arrigoni ◽  
O. Pastoris ◽  
R. F. Villa ◽  
M. Dossena ◽  
...  

The synaptosomal fractions obtained from the motor area of the cerebral cortex of normocapnic, normoxic, or hypoxic, untreated beagle dogs and of pentobarbital (Nembutal®)- or cytidine diphosphate (CDP)-choline-treated dogs were incubated and analyzed for ATP, ADP, AMP, creatine phosphate, pyruvate, and lactate. The data were compared with data obtained by the surface freezing technique from the whole contralateral cortical area. The in vivo intracarotid perfusion of the drug differentially affected the content of the metabolites and their ratio. This occurred whether the evaluations were performed in the incubated synaptosomal preparations or in whole cerebral tissue, both during normoxia and after hypoxia (15 min; Pao2 = 17–19 mm Hg). Thus intracarotid perfusion of nembutal increased the synaptosomal phosphorylation state both in normoxic and in hypoxic animals, whereas the effect on the metabolism of the contralateral cortical motor area as a whole was in all cases less than that observed in the synaptosomal fraction. Perfusion with CDP-choline increased synaptosomal phosphorylation after the hypoxic condition, but had no effect in normoxia or on the whole cortical tissue of the motor area. The possibility of obtaining a cerebral sparing action by utilizing molecules devoid of anesthetic action is suggested.


2020 ◽  
Vol 109 (1) ◽  
pp. 254-263 ◽  
Author(s):  
Irene Oddone ◽  
Andrea Arsiccio ◽  
Chinwe Duru ◽  
Kiran Malik ◽  
Jackie Ferguson ◽  
...  

2006 ◽  
Vol 18 (15) ◽  
pp. 3535-3542 ◽  
Author(s):  
K Bartel ◽  
D Nattland ◽  
A Kumar ◽  
S Dogel ◽  
W Freyland

1996 ◽  
Vol 76 (14) ◽  
pp. 2527-2530 ◽  
Author(s):  
Alexei V. Tkachenko ◽  
Yitzhak Rabin

2006 ◽  
Vol 110 (29) ◽  
pp. 14279-14282 ◽  
Author(s):  
Baoquan Xie ◽  
Haifeng Shi ◽  
Shichun Jiang ◽  
Ying Zhao ◽  
Charles C. Han ◽  
...  

2006 ◽  
Vol 39 (22) ◽  
pp. 7467-7470 ◽  
Author(s):  
Shishir Prasad ◽  
Laurie Hanne ◽  
Ali Dhinojwala

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