scholarly journals Wide-field Raman spectroscopic imaging with frequency modulation based spatially encoded light illumination

AIP Advances ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 095012
Author(s):  
Shenghan Ren ◽  
Tianyu Yan ◽  
Lin Wang ◽  
Nan Wang ◽  
Jimin Liang ◽  
...  
Keyword(s):  
Frequency Modulation ◽  
Spectroscopic Imaging ◽  
Light Illumination ◽  
Wide Field ◽  
Raman Spectroscopic

Fast wide-field Raman spectroscopic imaging based on simultaneous multi-channel image acquisition and Wiener estimation

2016 ◽  
Vol 41 (12) ◽  
pp. 2783 ◽  
Author(s):  
Dong Wei ◽  
Shuo Chen ◽  
Yi Hong Ong ◽  
Clint Perlaki ◽  
Quan Liu
Keyword(s):  
Image Acquisition ◽  
Spectroscopic Imaging ◽  
Wide Field ◽  
Raman Spectroscopic ◽  
Wiener Estimation ◽  
Channel Image

Recent Advances in Spontaneous Raman Spectroscopic Imaging: Instrumentation and Applications

2020 ◽  
Vol 27 (36) ◽  
pp. 6188-6207
Author(s):  
Nan Wang ◽  
Honghao Cao ◽  
Lin Wang ◽  
Feng Ren ◽  
Qi Zeng ◽  
...  
Keyword(s):  
Medicinal Chemistry ◽  
Spectroscopic Imaging ◽  
Chemical Imaging ◽  
High Spectral Resolution ◽  
Chemical Information ◽  
Wide Field ◽  
Scanning Method ◽  
Raman Spectroscopic ◽  
Recent Advances ◽  
Line Scanning

Background: Spectroscopic imaging based on the spontaneous Raman scattering effects can provide unique fingerprint information in relation to the vibration bands of molecules. Due to its advantages of high chemical specificity, non-invasive detection capability, low sensitivity to water, and no special sample pretreatment, Raman Spectroscopic Imaging (RSI) has become an invaluable tool in the field of biomedicine and medicinal chemistry. Methods: There are three methods to implement RSI, including point scanning, line scanning and wide-field RSI. Point-scanning can achieve two-and three-dimensional imaging of target samples. High spectral resolution, full spectral range and confocal features render this technique highly attractive. However, point scanning based RSI is a time-consuming process that can take several hours to map a small area. Line scanning RSI is an extension of point scanning method, with an imaging speed being 300-600 times faster. In the wide-field RSI, the laser illuminates the entire region of interest directly and all the images then collected for analysis. In general, it enables more accurate chemical imaging at faster speeds. Results: This review focuses on the recent advances in RSI, with particular emphasis on the latest developments on instrumentation and the related applications in biomedicine and medicinal chemistry. Finally, we prospect the development trend of RSI as well as its potential to translation from bench to bedside. Conclusion: RSI is a powerful technique that provides unique chemical information, with a great potential in the fields of biomedicine and medicinal chemistry.

Raman spectroscopic imaging with frequency modulation based spatially encoded light

2019 ◽  
Author(s):  
Tianyu Yan ◽  
Feiyang Lu ◽  
Duofang Chen ◽  
Yonghua Zhan ◽  
Jimin Liang ◽  
...  
Keyword(s):  
Frequency Modulation ◽  
Spectroscopic Imaging ◽  
Raman Spectroscopic

Raman spectroscopic imaging for investigations of de novo lipogenesis in hepatocellular carcinoma

2014 ◽  
Vol 52 (08) ◽  
Author(s):  
T Tolstik ◽  
C Marquardt ◽  
C Matthäus ◽  
C Beleites ◽  
C Krafft ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
De Novo ◽  
Spectroscopic Imaging ◽  
De Novo Lipogenesis ◽  
Raman Spectroscopic

Remote Raman spectroscopic imaging of human artery wall

1991 ◽  
Author(s):  
Darith Phat ◽  
Phat N. Vuong ◽  
Pascal Plaza ◽  
Francis Cheilan ◽  
Nguyen Q. Dao
Keyword(s):  
Spectroscopic Imaging ◽  
Artery Wall ◽  
Human Artery ◽  
Raman Spectroscopic
Sign in / Sign up

Export Citation Format

Share Document