Some biochemical markers and methylene tetrahydrofolate reductase gene polymorphism that association with different type of smoking

2020 ◽  
Author(s):  
Owayes Muaffaq Hamed Al-Hassani
2010 ◽  
Vol 38 (2) ◽  
pp. 991-996 ◽  
Author(s):  
Sulhattin Arslan ◽  
Sule Karadayi ◽  
Malik Ejder Yildirim ◽  
Ozturk Ozdemir ◽  
Ibrahim Akkurt

2010 ◽  
Vol 13 (1) ◽  
pp. 6-9 ◽  
Author(s):  
Olga Filippovna Sibireva ◽  
Ekaterina Yur'evna Khitrinskaya ◽  
Vadim Vital'evich Kalyuzhin ◽  
Aleksey Eduardovich Sazonov ◽  
Igor Ivanovich Ivanchuk ◽  
...  

Aim. To study prevalence, clinical and prognostic significance of prothrombotic genotypes pre-dominant in inborn thrombophilia in patients with diabeticnephropathy (DN). Materials and methods. A total of 90 patients with DN were examined; 54 and 36 cases suffered DM1 and DM2 respectively. Control group comprised100 healthy subjects. PCR was used to iden-tify single nucleotide substitution (C677T) in the methylene tetrahydrofolate reductase gene (MTHFR),point mutation in coagulation factor V gene (FV), and G202210A mutation in factor II gene (FII). Results. The probability of DN in patients with DM1 increases in the presence of Leiden mutation and in DM2 patients in the presence of single nucleotidesubstitu-tion (C677T) in MTHFR gene and G202210A mutation in the 3-untranslated region of FII. Conclusion. The prevalence of the above mutations associated with blood coagulation potential in DN patients is higher than in healthy subjects.Key words: diabetes mellitus, diabetic nephropathy, gene polymorphism, methylenetetrahydrofolate reductase


2010 ◽  
Vol 21 (1) ◽  
pp. 28-34 ◽  
Author(s):  
Azza AG Tantawy ◽  
Eman A El-Bostany ◽  
Amira AM Adly ◽  
Mohammed Abou El Asrar ◽  
Eman A El-Ghouroury ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document