scholarly journals Acceptor dopant mediated electrical property modification in Bi0.5Na0.5TiO3-based piezoceramic

2020 ◽  
Vol 128 (6) ◽  
pp. 064103
Author(s):  
Elaheh Taghaddos ◽  
Harry Charalambous ◽  
Steve Miller ◽  
Ahmad Safari
2015 ◽  
Vol 426 ◽  
pp. 99-102 ◽  
Author(s):  
Hyegyeong Kim ◽  
Eunsang Hwang ◽  
Doo-Yong Lee ◽  
Ji-Woong Kim ◽  
Jungseek Hwang ◽  
...  

2017 ◽  
Author(s):  
Jeremy Roach ◽  
Yusuke Sasano ◽  
Cullen Schmid ◽  
Saheem Zaidi ◽  
Vsevolod Katritch ◽  
...  

Salvinorin A (SalA) is a plant metabolite that agonizes the human <i>kappa</i>-opioid receptor (κ-OR) with high affinity and high selectivity over <i>mu- </i>and <i>delta-</i>opioid receptors. Its therapeutic potential has stimulated extensive semi-synthetic studies and total synthesis campaigns. However, structural modification of SalA has been complicated by its instability, and efficient total synthesis has been frustrated by its dense, complex architecture. Treatment of strategic bonds in SalA as dynamic and dependent on structural perturbation enabled the identification of an efficient retrosynthetic pathway. Here we show that deletion of C20 simultaneously stabilizes the SalA skeleton, simplifies its synthesis and retains its high affinity and selectivity for the κ-OR. The resulting 10-step synthesis now opens the SalA scaffold to deep-seated property modification.


2011 ◽  
Vol 30 (1) ◽  
pp. 238-240
Author(s):  
Xiu-lian He ◽  
Wen-jun Gao ◽  
Yi-cai Ji ◽  
Hong Lei ◽  
Shu-xi Gong

2021 ◽  
Vol 26 ◽  
pp. 102027
Author(s):  
Elnaz Esmizadeh ◽  
Ali Vahidifar ◽  
Sahar Shojaie ◽  
Ghasem Naderi ◽  
Mohammad Reza Kalaei ◽  
...  

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