An experimental model for pressure drop evaluation in a stenosed coronary artery

2020 ◽  
Vol 32 (2) ◽  
pp. 021901 ◽  
Author(s):  
Navid Freidoonimehr ◽  
Rey Chin ◽  
Anthony Zander ◽  
Maziar Arjomandi
Keyword(s):  
Coronary Artery ◽  
Pressure Drop ◽  
Experimental Model ◽  
Stenosed Coronary Artery

Numerical simulation of pulsatile blood flow characteristics in multi stenosed coronary artery

2021 ◽  
pp. 1-13
Author(s):  
Sarfaraz Kamangar
Keyword(s):  
Blood Flow ◽  
Shear Stress ◽  
Coronary Artery ◽  
Pressure Drop ◽  
Wall Shear Stress ◽  
Flow Characteristics ◽  
Stenosis Severity ◽  
Stress Zone ◽  
Wall Shear ◽  
Stenosed Coronary Artery

BACKGROUND: Coronary artery disease (CAD) is reported as one of the most common sources of death all over the world. The presence of stenosis (plaque) in the coronary arteries results in the restriction of blood supply, which leads to myocardial infarction. OBJECTIVE: The aim of this study was to investigate the effect of multi stenosis on hemodynamics parameters in idealized coronary artery models with varying degrees of stenosis and interspace distance between the stenosis. METHODS: A finite volume-based software package (ANSYS CFX 17.2) was employed to model the blood flow. The hemodynamic stenosis parameters of blood, such as the pressure, velocity, and wall shear stress were obtained. RESULTS: The computed results showed that the pressure drop is maximum across the 90% area stenosis (AS). The pressure drop is increased as the distance between the proximal and distal stenosis is decreased across the proximal stenosis for the model P70_D70 durign the systolic period of the cardiac cycle. A recirculation zone is formed behind the stenosis and is restricted by the occurrence of distal stenosis as the interspacing distance decreases, which could lead to further progression of stenosis in the flow-disturbed area. The wall shear stress was found to increase as the distance between the proximal and distal stenosis is increased across the distal stenosis. The maximum wall shear stress was found at the 90% AS. CONCLUSIONS: In the clinical diagnosis an overestimation of distal stenosis severity could be possible. Furthermore, the low wall shear stress zone in between the proximal and distal stenosis may help atherosclerotic growth or merging of adjacent stenosis.

Effect of shape of the stenosis on the hemodynamics of a stenosed coronary artery

2021 ◽  
Vol 33 (8) ◽  
pp. 081914
Author(s):  
Navid Freidoonimehr ◽  
Rey Chin ◽  
Anthony Zander ◽  
Maziar Arjomandi
Keyword(s):  
Coronary Artery ◽  
Stenosed Coronary Artery

Effect of Stenosis Eccentricity in a Model of Bifurcated Coronary Artery

2014 ◽  
Vol 553 ◽  
pp. 332-337
Author(s):  
Babak Fakhim ◽  
Ashkan Javadzadegan ◽  
Rahman T. Nakkas ◽  
Masud Behnia
Keyword(s):  
Regression Analysis ◽  
Coronary Artery ◽  
Pressure Drop ◽  
Linear Regression ◽  
Left Coronary Artery ◽  
Linear Regression Analysis ◽  
Recirculation Flow ◽  
Structure Interaction ◽  
Recirculation Area ◽  
Flow Pressure

This study was to implement fluid structure interaction (FSI) method in order toinvestigate the effect of stenosis eccentricity on the recirculation flow, pressure drop and wall shearstress (WSS) in an atherosclerotic model of a left coronary artery with left anterior descending(LAD) and left circumflex (LCX) branches. The linear regression analysis results showed a positivecorrelation between WSS and stenosis eccentricity. The results also showed that the stenosiseccentricity plays a prominent role in determining the pressure drop and recirculation area, whilehaving relatively unnoticeable effects on WSS.

scholarly journals Numerical Simulation of Dispersed Particle-Blood Flow in the Stenosed Coronary Arteries

2018 ◽  
Vol 2018 ◽  
pp. 1-16 ◽  
Author(s):  
Mongkol Kaewbumrung ◽  
Somsak Orankitjaroen ◽  
Pichit Boonkrong ◽  
Buraskorn Nuntadilok ◽  
Benchawan Wiwatanapataphee
Keyword(s):  
Numerical Simulation ◽  
Blood Flow ◽  
Shear Stress ◽  
Coronary Artery ◽  
Pressure Drop ◽  
Wall Shear Stress ◽  
Stokes Equations ◽  
Spherical Shape ◽  
Shear Stresses ◽  
Wall Shear

A mathematical model of dispersed bioparticle-blood flow through the stenosed coronary artery under the pulsatile boundary conditions is proposed. Blood is assumed to be an incompressible non-Newtonian fluid and its flow is considered as turbulence described by the Reynolds-averaged Navier-Stokes equations. Bioparticles are assumed to be spherical shape with the same density as blood, and their translation and rotational motions are governed by Newtonian equations. Impact of particle movement on the blood velocity, the pressure distribution, and the wall shear stress distribution in three different severity degrees of stenosis including 25%, 50%, and 75% are investigated through the numerical simulation using ANSYS 18.2. Increasing degree of stenosis severity results in higher values of the pressure drop and wall shear stresses. The higher level of bioparticle motion directly varies with the pressure drop and wall shear stress. The area of coronary artery with higher density of bioparticles also presents the higher wall shear stress.

scholarly journals Effect of Wall Flexibility on the Deformation during Flow in a Stenosed Coronary Artery

Fluids ◽  
2017 ◽  
Vol 2 (2) ◽  
pp. 16 ◽  
Author(s):  
Laxman Kallekar ◽  
Chinthapenta Viswanath ◽  
Mohan Anand
Keyword(s):  
Coronary Artery ◽  
Wall Flexibility ◽  
Stenosed Coronary Artery
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