Numerical simulation of pulsatile blood flow characteristics in multi stenosed coronary artery

2021 ◽  
pp. 1-13
Author(s):  
Sarfaraz Kamangar
Keyword(s):  
Blood Flow ◽  
Shear Stress ◽  
Coronary Artery ◽  
Pressure Drop ◽  
Wall Shear Stress ◽  
Flow Characteristics ◽  
Stenosis Severity ◽  
Stress Zone ◽  
Wall Shear ◽  
Stenosed Coronary Artery

BACKGROUND: Coronary artery disease (CAD) is reported as one of the most common sources of death all over the world. The presence of stenosis (plaque) in the coronary arteries results in the restriction of blood supply, which leads to myocardial infarction. OBJECTIVE: The aim of this study was to investigate the effect of multi stenosis on hemodynamics parameters in idealized coronary artery models with varying degrees of stenosis and interspace distance between the stenosis. METHODS: A finite volume-based software package (ANSYS CFX 17.2) was employed to model the blood flow. The hemodynamic stenosis parameters of blood, such as the pressure, velocity, and wall shear stress were obtained. RESULTS: The computed results showed that the pressure drop is maximum across the 90% area stenosis (AS). The pressure drop is increased as the distance between the proximal and distal stenosis is decreased across the proximal stenosis for the model P70_D70 durign the systolic period of the cardiac cycle. A recirculation zone is formed behind the stenosis and is restricted by the occurrence of distal stenosis as the interspacing distance decreases, which could lead to further progression of stenosis in the flow-disturbed area. The wall shear stress was found to increase as the distance between the proximal and distal stenosis is increased across the distal stenosis. The maximum wall shear stress was found at the 90% AS. CONCLUSIONS: In the clinical diagnosis an overestimation of distal stenosis severity could be possible. Furthermore, the low wall shear stress zone in between the proximal and distal stenosis may help atherosclerotic growth or merging of adjacent stenosis.

scholarly journals Numerical Simulation of Dispersed Particle-Blood Flow in the Stenosed Coronary Arteries

2018 ◽  
Vol 2018 ◽  
pp. 1-16 ◽  
Author(s):  
Mongkol Kaewbumrung ◽  
Somsak Orankitjaroen ◽  
Pichit Boonkrong ◽  
Buraskorn Nuntadilok ◽  
Benchawan Wiwatanapataphee
Keyword(s):  
Numerical Simulation ◽  
Blood Flow ◽  
Shear Stress ◽  
Coronary Artery ◽  
Pressure Drop ◽  
Wall Shear Stress ◽  
Stokes Equations ◽  
Spherical Shape ◽  
Shear Stresses ◽  
Wall Shear

A mathematical model of dispersed bioparticle-blood flow through the stenosed coronary artery under the pulsatile boundary conditions is proposed. Blood is assumed to be an incompressible non-Newtonian fluid and its flow is considered as turbulence described by the Reynolds-averaged Navier-Stokes equations. Bioparticles are assumed to be spherical shape with the same density as blood, and their translation and rotational motions are governed by Newtonian equations. Impact of particle movement on the blood velocity, the pressure distribution, and the wall shear stress distribution in three different severity degrees of stenosis including 25%, 50%, and 75% are investigated through the numerical simulation using ANSYS 18.2. Increasing degree of stenosis severity results in higher values of the pressure drop and wall shear stresses. The higher level of bioparticle motion directly varies with the pressure drop and wall shear stress. The area of coronary artery with higher density of bioparticles also presents the higher wall shear stress.

scholarly journals Investigation of blood flow through an artery in the presence of overlapping stenosis

2017 ◽  
Vol 14 (1) ◽  
pp. 39-46 ◽  
Author(s):  
K. Maruthi Prasad ◽  
S. Thulluri ◽  
M. V. Phanikumari
Keyword(s):  
Blood Flow ◽  
Shear Stress ◽  
Pressure Drop ◽  
Wall Shear Stress ◽  
Couple Stress ◽  
Flow Characteristics ◽  
Couple Stress Fluid ◽  
Flow Equations ◽  
Wall Shear ◽  
Fluid Parameters

The effects of an overlapping stenosis on blood flow characteristics in an artery have been studied. Blood has been represented by a couple stress fluid. The flow equations have been linearised and the expressions for pressure drop, resistance to the flow and wall shear stress have been derived. The results are shown graphically. It is observed that the resistance to the flow, pressure drop and wall shear stress increases with height and length of the stenosis. And it is noticed that the resistance to the flow and pressure drop decreases with couple stress fluid parameters. But wall shear stress increases with couple stress fluid parameters.

scholarly journals Analysis of Flow Characteristics of the Blood Flowing through an Inclined Tapered Porous Artery with Mild Stenosis under the Influence of an Inclined Magnetic Field

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Neetu Srivastava
Keyword(s):  
Magnetic Field ◽  
Blood Flow ◽  
Shear Stress ◽  
Wall Shear Stress ◽  
Flow Rate ◽  
Flow Characteristics ◽  
Volumetric Flow Rate ◽  
Mhd Equations ◽  
Inclined Magnetic Field ◽  
Wall Shear

Analytical investigation of MHD blood flow in a porous inclined stenotic artery under the influence of the inclined magnetic field has been done. Blood is considered as an electrically conducting Newtonian fluid. The physics of the problem is described by the usual MHD equations along with appropriate boundary conditions. The flow governing equations are finally transformed to nonhomogeneous second-order ordinary differential equations. This model is consistent with the principles of magnetohydrodynamics. Analytical expressions for the velocity profile, volumetric flow rate, wall shear stress, and pressure gradient have been derived. Blood flow characteristics are computed for a specific set of values of the different parameters involved in the model analysis and are presented graphically. Some of the obtained results show that the flow patterns in converging region (ξ<0), diverging region (ξ>0), and nontapered region (ξ=0) are effectively influenced by the presence of magnetic field and change in inclination of artery as well as magnetic field. There is also a significant effect of permeability on the wall shear stress as well as volumetric flow rate.

Effect of aortic spiral blood flow on wall shear stress in stenosed left main coronary arteries with varying take-off angle, stenosis severity and eccentricity

2018 ◽  
Vol 32 (8) ◽  
pp. 4003-4011 ◽  
Author(s):  
Abouzar Moshfegh ◽  
Ashkan Javadzadegan ◽  
Zhaoqi Zhang ◽  
Hamid Hassanzadeh Afrouzi ◽  
Mohammad Omidi
Keyword(s):  
Blood Flow ◽  
Shear Stress ◽  
Wall Shear Stress ◽  
Coronary Arteries ◽  
Left Main ◽  
Stenosis Severity ◽  
Wall Shear

Fluid-Structure Interaction Analysis on the Effects of Bifurcation Angle Asymmetry in a Left Main Coronary Artery Model

2014 ◽  
Vol 553 ◽  
pp. 316-321
Author(s):  
Ashkan Javadzadegan ◽  
Babak Fakhim ◽  
Rahman T. Nakkas ◽  
Masud Behnia
Keyword(s):  
Shear Stress ◽  
Coronary Artery ◽  
Pressure Drop ◽  
Wall Shear Stress ◽  
Interaction Analysis ◽  
Linear Regression Analysis ◽  
Recirculation Flow ◽  
Bifurcation Angle ◽  
Recirculation Area ◽  
Wall Shear

This study was to investigate the effect of the bifurcation angle asymmetry on recirculation flow, pressure drop and wall shear stress (WSS) in an atherosclerotic model of a left coronary artery with left anterior descending (LAD) and left circumflex (LCX) branches. The linear regression analysis results showed that there is a positive correlation between WSS and bifurcation angle asymmetry. However, small increase in the WSS magnitude due to the increase in bifurcation angle asymmetry revealed the angle asymmetry does not seem to have a profound effect on the WSS. The results also showed that the bifurcation angle asymmetry play a prominent role in determining the pressure drop and recirculation area, while having relatively unnoticeable effects on the wall shear stress (WSS).

Computational Modeling of Non-Newtonian Blood Flow Through Stenosed Arteries in the Presence of Magnetic Field

2013 ◽  
Vol 135 (11) ◽  
Author(s):  
Aiman Alshare ◽  
Bourhan Tashtoush ◽  
Hossam H. El-Khalil
Keyword(s):  
Magnetic Field ◽  
Blood Flow ◽  
Shear Stress ◽  
Pressure Drop ◽  
Wall Shear Stress ◽  
Field Strength ◽  
Magnetic Field Strength ◽  
Stenosed Artery ◽  
Flow Through ◽  
Wall Shear

Steady flow simulations of blood flow in an axisymmetric stenosed artery, subjected to a static magnetic field, are performed to investigate the influence of artery size, magnetic field strength, and non-Newtonian behavior on artery wall shear stress and pressure drop in the stenosed section. It is found that wall shear stress and pressure drop increase by decreasing artery size, assuming non-Newtonian fluid, and increasing magnetic field strength. In the computations, the shear thinning behavior of blood is accounted for by the Carreau–Yasuda model. Computational results are compared and found to be inline with available experimental data.

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