scholarly journals Generation of perfusable hollow calcium alginate microfibers with a double co-axial flow capillary microfluidic device

2019 ◽  
Vol 13 (6) ◽  
pp. 064108
Author(s):  
Chongjian Gao ◽  
Xuedong Wang ◽  
Qian Du ◽  
Junying Tang ◽  
Jiahuan Jiang
Keyword(s):  
Microfluidic Device ◽  
Calcium Alginate ◽  
Axial Flow ◽  
Alginate Microfibers ◽  
Flow Capillary

Hydrodynamic alignment and microfluidic spinning of strength-reinforced calcium alginate microfibers

2018 ◽  
Vol 230 ◽  
pp. 148-151 ◽  
Author(s):  
Xili Hu ◽  
Mingwei Tian ◽  
Bing Sun ◽  
Lijun Qu ◽  
Shifeng Zhu ◽  
...  
Keyword(s):  
Calcium Alginate ◽  
Alginate Microfibers

Shape-Controlled Production of Biodegradable Calcium Alginate Gel Microparticles Using a Novel Microfluidic Device

Langmuir ◽  
2006 ◽  
Vol 22 (22) ◽  
pp. 9453-9457 ◽  
Author(s):  
Kan Liu ◽  
Hui-Jiang Ding ◽  
Jing Liu ◽  
Yong Chen ◽  
Xing-Zhong Zhao
Keyword(s):  
Microfluidic Device ◽  
Calcium Alginate ◽  
Alginate Gel ◽  
Calcium Alginate Gel ◽  
Shape Controlled

scholarly journals Rapid and cost-effective fabrication of selectively permeable calcium-alginate microfluidic device using “modified” embedded template method

2012 ◽  
Vol 6 (1) ◽  
pp. 012821 ◽  
Author(s):  
Amit Asthana ◽  
Kwang Ho Lee ◽  
Kyeong-Ohn Kim ◽  
Dong-Myung Kim ◽  
Dong-Pyo Kim
Keyword(s):  
Microfluidic Device ◽  
Calcium Alginate ◽  
Cost Effective ◽  
Template Method

Polymorphic calcium alginate microfibers assembled using a programmable microfluidic field for cell regulation

Lab on a Chip ◽  
2020 ◽  
Vol 20 (17) ◽  
pp. 3158-3166
Author(s):  
Qiwei Huang ◽  
Yingyi Li ◽  
Longfei Fan ◽  
John H. Xin ◽  
Hui Yu ◽  
...  
Keyword(s):  
Microfluidic Chip ◽  
Calcium Alginate ◽  
Cell Regulation ◽  
Fluid Field ◽  
Complex Fluid ◽  
Alginate Microfibers

A single microfluidic chip was used to control a complex fluid field to prepare polymorphic microfibers for cell regulation.

A microfluidic device approach to generate hollow alginate microfibers with controlled wall thickness and inner diameter

2015 ◽  
Vol 117 (21) ◽  
pp. 214703 ◽  
Author(s):  
Uyen H. T. Pham ◽  
Madiha Hanif ◽  
Amit Asthana ◽  
Samir M. Iqbal
Keyword(s):  
Microfluidic Device ◽  
Wall Thickness ◽  
Inner Diameter ◽  
Alginate Microfibers

scholarly journals Shear at Fluid-Fluid Interfaces Affects the Surface Topologies of Alginate Microfibers

2019 ◽  
Vol 1 (1) ◽  
pp. 265-272 ◽  
Author(s):  
Marilyn C. McNamara ◽  
Ryan J. Pretzer ◽  
Reza Montazami ◽  
Nicole N. Hashemi
Keyword(s):  
Microfluidic Device ◽  
Shear Force ◽  
Three Dimensional ◽  
Surface Topology ◽  
Fluid Interfaces ◽  
Animal Testing ◽  
Simple Modification ◽  
Core Solution ◽  
Tunable Mechanical Properties ◽  
Alginate Microfibers

Hydrogel microfibers have great potential for applications such as tissue engineering or three-dimensional cell culturing. Their favorable attributes can lead to tissue models that can help to reduce or eliminate animal testing, thereby providing an eco-friendly alternative to this unsustainable process. In addition to their highly tunable mechanical properties, this study shows that varying the viscosity and flow rates of the prepolymer core solution and gellator sheath solution within a microfluidic device can affect the surface topology of the resulting microfibers. Higher viscosity core solutions are more resistant to deformation from shear force within the microfluidic device, thereby yielding smoother fibers. Similarly, maintaining a smaller velocity gradient between the fluids within the microfluidic device minimizes shear force and smooths fiber surfaces. This simple modification provides insight into manufacturing microfibers with highly tunable properties.

Mechanical properties of calcium alginate fibers produced with a microfluidic device

2012 ◽  
Vol 89 (4) ◽  
pp. 1198-1206 ◽  
Author(s):  
Teresa R. Cuadros ◽  
Olivier Skurtys ◽  
José M. Aguilera
Keyword(s):  
Mechanical Properties ◽  
Microfluidic Device ◽  
Calcium Alginate ◽  
Alginate Fibers

Preparation of calcium alginate microbeads from water-in-oil-in-water emulsions using microfluidic device

2009 ◽  
Vol 108 ◽  
pp. S162 ◽  
Author(s):  
Daisuke Saeki ◽  
Shinji Sugiura ◽  
Toshiyuki Kanamori ◽  
Seigo Sato ◽  
Sosaku Ichikawa
Keyword(s):  
Microfluidic Device ◽  
Calcium Alginate ◽  
Oil In Water

scholarly journals Preparation of hydrogel calcium-alginate microparticles via microfluidic device for Cu2+ treatment

2020 ◽  
Vol 9 (1) ◽  
pp. 60-66
Author(s):  
Trung Dang Cu ◽  
Phuong Le Ha ◽  
Hong Hoang Thu ◽  
Mai Mac Thi Thu ◽  
Vu Tran Khac ◽  
...  
Keyword(s):  
Size Distribution ◽  
Sodium Alginate ◽  
Microfluidic Device ◽  
Flow Rate ◽  
Calcium Alginate ◽  
Cell Encapsulation ◽  
Alginate Hydrogel ◽  
Experimental Conditions ◽  
Hydrogel Microparticles ◽  
Calcium Alginate Hydrogel

Alginate-based hydrogels are attracted much attention in biomedical and chemical field, and their size and shape are significant to their applications like drug delivery and cell encapsulation. Monodisperse sodium alginate microdroplets are produced using a flow-focusing microfluidic device (MFFD) by adjusting the flow rate on the continuous phase (soybean oil) and the dispersed phase (sodium alginate solution). The external gelation process of sodium alginate microdroplets occurs outside the chanel in a calcium chloride solution to form calcium alginate hydrogel particales. The shape, size and size distribution of these calcium alginate hydrogel particles depend strongly on the flow rate inside the MFFD. By optimizing the parameters, the hydrogel microparticles were obtained with diameters ranging from 70 µm to 100 µm with size distribution under 10%, depending on experimental conditions. The removal of Cu2+ ions by the absorption of hydrogel microparticles was also demonstrated.

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