Reflection-mode continuous-wave 0.15λ-resolution terahertz solid immersion microscopy of soft biological tissues

2018 ◽  
Vol 113 (11) ◽  
pp. 111102 ◽  
Author(s):  
N. V. Chernomyrdin ◽  
A. S. Kucheryavenko ◽  
G. S. Kolontaeva ◽  
G. M. Katyba ◽  
I. N. Dolganova ◽  
...  
Keyword(s):  
Continuous Wave ◽  
Biological Tissues ◽  
Reflection Mode ◽  
Soft Biological Tissues

scholarly journals Continuous-Wave THz Imaging for Biomedical Samples

2020 ◽  
Vol 11 (1) ◽  
pp. 71
Author(s):  
Yaya Zhang ◽  
Chuting Wang ◽  
Bingxin Huai ◽  
Shiyu Wang ◽  
Yating Zhang ◽  
...  
Keyword(s):  
Medical Imaging ◽  
Biomedical Imaging ◽  
Continuous Wave ◽  
Biological Tissues ◽  
Thz Spectroscopy ◽  
Label Free ◽  
Thz Imaging ◽  
Malignant Tumours ◽  
Advantages And Disadvantages ◽  
Imaging Application

In the past few decades, the applications of terahertz (THz) spectroscopy and imaging technology have seen significant developments in the fields of biology, medical diagnosis, food safety, and nondestructive testing. Label-free diagnosis of malignant tumours has been obtained and also achieved significant development in THz biomedical imaging. This review mainly presents the research status and prospects of several common continuous-wave (CW) THz medical imaging systems and applications of THz medical imaging in biological tissues. Here, we first introduce the properties of THz waves and how these properties play a role in biomedical imaging. Then, we analyse both the advantages and disadvantages of the CW THz imaging methods and the progress of these methods in THz biomedical imaging in recent ten years. Finally, we summarise the obstacles in the way of the application of THz bio-imaging application technology in clinical detection, which need to be investigated and overcome in the future.

Propagation of surface acoustic waves in the models of soft biological tissues

1992 ◽  
Vol 25 (7) ◽  
pp. 814
Author(s):  
Vladimir V. Shorokhov ◽  
Vadim N. Voronkov ◽  
Alexander N. Klishko
Keyword(s):  
Acoustic Waves ◽  
Surface Acoustic Waves ◽  
Biological Tissues ◽  
Soft Biological Tissues

Spherical indentation load-relaxation of soft biological tissues

2006 ◽  
Vol 21 (8) ◽  
pp. 2003-2010 ◽  
Author(s):  
Jason M. Mattice ◽  
Anthony G. Lau ◽  
Michelle L. Oyen ◽  
Richard W. Kent
Keyword(s):  
Costal Cartilage ◽  
Kidney Tissue ◽  
Biological Tissues ◽  
Indentation Load ◽  
Spherical Indentation ◽  
Load Relaxation ◽  
Soft Biological Tissues ◽  
Long Time ◽  
Constant Displacement ◽  
Soft Biological Materials

Elastic-viscoelastic correspondence was used to generate displacement–time solutions for spherical indentation testing of soft biological materials with time-dependent mechanical behavior. Boltzmann hereditary integral operators were used to determine solutions for indentation load-relaxation following a constant displacement rate ramp. A “ramp correction factor” approach was used for routine analysis of experimental load-relaxation data. Experimental load-relaxation tests were performed on rubber, as well as kidney tissue and costal cartilage, two hydrated soft biological tissues with vastly different mechanical responses. The experimental data were fit to the spherical indentation ramp-relaxation solutions to obtain values of short- and long-time shear modulus and of material time constants. The method is used to demonstrate linearly viscoelastic responses in rubber, level-independent indentation results for costal cartilage, and age-independent indentation results for kidney parenchymal tissue.

scholarly journals Численное моделирование миграции фотонов в однородных и неоднородных цилиндрических фантомах

2020 ◽  
Vol 128 (6) ◽  
pp. 832
Author(s):  
А.Ю. Потлов ◽  
С.В. Фролов ◽  
С.Г. Проскурин
Keyword(s):  
Radiation Transfer ◽  
Biological Tissues ◽  
Photon Density ◽  
Radiation Transfer Equation ◽  
Scattering Media ◽  
Soft Biological Tissues ◽  
Photon Diffusion ◽  
Low Coherence ◽  
The Brain ◽  
Pulsed Irradiation

The specific features of photon diffusion of low-coherence pulsed irradiation in phantoms of soft biological tissues (blood-saturated tissues of the brain, breast, etc.) are described. The results of photon migration simulation using the Diffusion Approximation to the Radiation Transfer Equation (RTE) are compared with ones of the Monte Carlo simulations. It has been confirmed that the Photon Density Normalized Maximum (PDNM) moves towards the center of the investigated object in case of relatively uniform and strongly scattering media. In the presence of inhomogeneities, type of the PDNM motion changes drastically. Presence of an absorbing inhomogeneity in the medium directs trajectory of the PDNM motion of towards the point symmetric to the inhomogeneity relative to the geometric center of the investigated object. In case of scattering the PDNM moves toward the direction of the center of the scattering inhomogeneity.

Equivalent Mixed “PHETS” and “MPHETS” Poroelasttc-Transport-Swelling Finite Element Models for Soft Biological Tissues

1999 ◽  
Author(s):  
B. R. Simon ◽  
S. K. Williams ◽  
J. Liu ◽  
J. W. Nichol ◽  
P. H. Rigby ◽  
...  
Keyword(s):  
Finite Element ◽  
Chemical Potential ◽  
Biological Tissues ◽  
Finite Element Models ◽  
Material Interfaces ◽  
Soft Biological Tissues ◽  
Fibrous Matrix ◽  
Charged Species ◽  
Pressure Fields ◽  
Swelling Model

Abstract A soft hydrated tissue structure can be viewed as a “PETS” (poroelastic-transport-swelling) model, i.e., as a continuum composed of an incompressible porous solid (fibrous matrix with fixed charge density, FCD) that is saturated by a mobile incompressible fluid (water) containing mobile positively (p) and negatively (m) charged species. Previously, we described two PETS models — a “semi-mixed” porohyperelastic PHETS model (Simon et al. 1998) and a “fully mixed” MPHETS model (Simon et al. 1999) using FEMs (finite element models) that included geometric and material nonlinearity and coupled electrical/chemical/mechanical transport of the fluid and charged species. Here, we demonstrate the equivalence of the PHETS and MPHETS formulations that are useful when the solid and fluid materials are incompressible and the electrical-chemical potential and mechanical-osmotic pressure fields are discontinuous at material interfaces.

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