Surface-conduction enhanced dielectrophoretic-like particle migration in electric-field driven fluid flow through a straight rectangular microchannel

2017 ◽  
Vol 29 (10) ◽  
pp. 102001 ◽  
Author(s):  
Zhijian Liu ◽  
Di Li ◽  
Yongxin Song ◽  
Xinxiang Pan ◽  
Dongqing Li ◽  
...  
Author(s):  
Miad Yazdani ◽  
Jamal Seyed-Yagoobi

The control of fluid flow distribution in micro-scale tubes is numerically investigated. The flow distribution control is achieved via electric conduction mechanism. In electrohydrodynamic (EHD) conduction pumping, when an electric field is applied to a fluid, dissociation and recombination of electrolytic species produces heterocharge layers in the vicinity of electrodes. Attraction between electrodes and heterocharge layers induces a fluid motion and a net flow is generated if the electrodes are asymmetric. The numerical domain comprises a 2-D manifold attached to two bifurcated tubes with one of the tubes equipped with a bank of uniquely designed EHD-conduction electrodes. In the absence of electric field, the total flow supplied at the manifold’s inlet is equally distributed among the tubes. The EHD-conduction, however, operates as a mechanism to manipulate the flow distribution to allow the flow through one branch surpasses the counterpart of the other branch. Its performance is evaluated under various operating conditions.


Micromachines ◽  
2019 ◽  
Vol 10 (4) ◽  
pp. 247 ◽  
Author(s):  
Ying-Jie Lo ◽  
U Lei

In contrast to the delicate 3D electrodes in the literature, a simple flow-through device is proposed here for continuous and massive lysis of cells using electricity. The device is essentially a rectangular microchannel with a planar electrode array built on its bottom wall, actuated by alternating current (AC) voltages between neighboring electrodes, and can be incorporated easily into other biomedical systems. Human whole blood diluted 10 times with phosphate-buffered saline (about 6 × 108 cells per mL) was pumped through the device, and the cells were completely lysed within 7 s after the application of a 20 V peak-to-peak voltage at 1 MHz, up to 400 μL/hr. Electric field and Maxwell stress were calculated for assessing electrical lysis. Only the lower half-channel was exposed to an electric field exceeding the irreversible threshold value of cell electroporation (Eth2), suggesting that a cross flow, proposed here primarily as the electro-thermally induced flow, was responsible for bringing the cells in the upper half-channel downward to the lower half-channel. The Maxwell shear stress associated with Eth2 was one order of magnitude less than the threshold mechanical stresses for lysis, implying that an applied moderate mechanical stress could aid electrical lysis.


2021 ◽  
Author(s):  
Md. Fazlay Rubby ◽  
Mohammad Salman Parvez ◽  
Prosanto Biswas ◽  
Hasina F. Huq ◽  
Nazmul Islam

2016 ◽  
Vol 19 (5) ◽  
pp. 391-404 ◽  
Author(s):  
B. M. Shankar ◽  
I. S. Shivakumara ◽  
Chiu-On Ng

2014 ◽  
Vol 17 (11) ◽  
pp. 1019-1029 ◽  
Author(s):  
Mohammad Zafari ◽  
Masoud Panjepour ◽  
Mohsen Davazdah Emami ◽  
Mahmood Meratian

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