scholarly journals A multiplexed immunoaggregation biomarker assay using a two-stage micro resistive pulse sensor

2016 ◽  
Vol 10 (2) ◽  
pp. 024109 ◽  
Author(s):  
Y. Han ◽  
H. Wu ◽  
F. Liu ◽  
G. Cheng ◽  
J. Zhe
Keyword(s):  
Two Stage ◽  
Resistive Pulse ◽  
Pulse Sensor

Size-based cell sorting with a resistive pulse sensor and an electromagnetic pump in a microfluidic chip

2014 ◽  
Vol 36 (3) ◽  
pp. 398-404 ◽  
Author(s):  
Yongxin Song ◽  
Mengqi Li ◽  
Xinxiang Pan ◽  
Qi Wang ◽  
Dongqing Li
Keyword(s):  
Microfluidic Chip ◽  
Cell Sorting ◽  
Electromagnetic Pump ◽  
Resistive Pulse ◽  
Pulse Sensor

Detection of Individual Molecules and Ions by Carbon Nanotube-Based Differential Resistive Pulse Sensor

Small ◽  
2018 ◽  
Vol 14 (15) ◽  
pp. 1800013 ◽  
Author(s):  
Ran Peng ◽  
Xiaowu Shirley Tang ◽  
Dongqing Li
Keyword(s):  
Carbon Nanotube ◽  
Resistive Pulse ◽  
Pulse Sensor

scholarly journals A Simple Displacement Aptamer Assay on Resistive Pulse Sensor for Small Molecule Detection

2020 ◽  
Author(s):  
Rhushabh Maugi ◽  
bernadette gamble ◽  
david bunka ◽  
Mark Platt
Keyword(s):  
Small Molecules ◽  
Small Molecule ◽  
Label Free ◽  
Resistive Pulse ◽  
Pulse Sensor ◽  
Label Free Detection ◽  
Ssdna Aptamer ◽  
Aptamer Assay ◽  
Small Molecule Detection ◽  
Surface Changes

A universal aptamer-based sensing strategy is proposed using DNA modified nanocarriers and Resistive Pulse Sensing for the rapid and label free detection of small molecules. The surface of a magnetic nanocarrier was first modified with a ssDNA aka linker which is designed to be partially complimentary in sequence to a ssDNA aptamer. The aptamer and linker form a stable dsDNA complex on the nanocarriers surface. Upon the addition of the target molecule, a conformational change takes place where the aptamer preferentially binds to the target over the linker; causing the aptamer to be released into solution. The RPS measures the change in velocity of the nanocarrier as its surface changes from dsDNA to ssDNA, and its velocity is used as a proxy for the concentration of the target. We illustrate the versatility of the assay by demonstrating the detection of the antibiotic Moxifloxacin, and chemotherapeutics Imatinib and Irinotecan.

Nanoparticle detection by microfluidic resistive pulse sensor with optical evidence

2010 ◽  
Author(s):  
Hongpeng Zhang ◽  
Yongxin Song ◽  
Xinxiang Pan ◽  
Yuqing Sun ◽  
Dongqing Li ◽  
...  
Keyword(s):  
Nanoparticle Detection ◽  
Resistive Pulse ◽  
Pulse Sensor ◽  
Optical Evidence
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