Biodegradation rate of shellac coated bovine hydroxyapatite for bone filler material

2016 ◽  
Author(s):  
Joko Triyono ◽  
Triyono ◽  
Endang Susilowati ◽  
Suci Anindya Murdiyantara
Keyword(s):  
Filler Material ◽  
Biodegradation Rate ◽  
Bone Filler ◽  
Bovine Hydroxyapatite

scholarly journals Karakterisasi Material Biokomposit Bovine Hidroksapatit (BHA)/Shellac dan Kitosan Sebagai Material Bone Filler

ROTASI ◽  
2017 ◽  
Vol 19 (2) ◽  
pp. 82
Author(s):  
Junaidi Rasid ◽  
Joko Triyono ◽  
Teguh Triyono
Keyword(s):  
Bovine Bone ◽  
Test Results ◽  
X Ray Diffraction ◽  
Calcination Process ◽  
X Ray ◽  
Medical Needs ◽  
Bone Filler ◽  
Bone Powder ◽  
Bovine Hydroxyapatite ◽  
Scanning Electron

Development of composite materials is growing rapidly to support medical needs. Biocomposite was made from bovine bone powder/shellac/chitosan for bone filler applications. Biocomposite of BHA(Bovine Hydroxyapatite)/shellac/chitosan was derived of bovine bone powder coated with shellac 10 ml. Mixed variation between BHA/shellac and chitosan i.e 30:40, 40:60, 50:50, 60:40, 70:30 %wt  were synthesized by dry method. Samples of BHA/shellac/chitosan were compacted with the pressure 60 bar until becomes solid with the cylinder mold 13 mm and 8 mm in thickness, the calcination process on temperature of  900ºC for 2 hours and increased temperature is 10ºC/min. Test XRD (X-Ray Diffraction), Microvickers, DTS (Diametric Tensile Strength) and SEM (Scanning Electron Microschopy), Density, and Porosity. XRD test results showed that bovine powder has become BHA (Bovine Hydroxyapatite), microvickers test of sample BHA/shellac/chitosan for maximum was 7.47 ± 0.685 VHN and 0.182 ± 3.73 VHN for minimum, DTS test of sample BHA/shellac/chitosan maximum at 36.66 ± 9.01 KPa and minimum at 13.90 ± 1.24 KPa. Porous observations with SEM toward sample BHA/shellac/chitosan porous size and number of samples contained at BHA/shellac/chitosan is 70:30 wt%. Density test with  highest value was 1,168gr/cm3, and lowest 1,070 gr/cm3. Highest porosity value at variation 50/50 %wt = 0,988%, and the lowest at 70/30 %wt = 0,977%

scholarly journals Pengaruh Variasi HA-TCP (Hydroxy Apatit-Tricalcium Pospat) Terhadap Biokomposit (HA:TCP)-Gelatin-CMC Sebagai Injectable Bone Subtitute (IBS)

2018 ◽  
Vol 4 (1) ◽  
pp. 24-30
Author(s):  
Gani Purwiandono ◽  
Hera Julita ◽  
Dita Adi Saputra
Keyword(s):  
Density Increase ◽  
Filler Material ◽  
Sample Mass ◽  
Bone Filler ◽  
High Tension

The synthesis of biocomposite (HA:TCP) – Gelatine – CMC for bone filler material has been carried out. In this research, the ratio of HA and TCP was varied as follows: 70:30, 50:50 and 40:60. The decrease of HA and the increase of TCP concentration will decrease the density, increase the percentage of porosity and swelling. The best composition for the synthesis was obtained for sample B with the ratio of HA:TCP = 50:50. For sample B, the synthesized biocomposite has the density of 1.67790 gr/cm3, porosity of 78.64%, tension of 10.14 MPa, swelling ability  46.85% and the sample mass degradation percentage of 8.1 %. The composition used for the biocomposite synthesis in this research was suitable to be applied as bone filler material which needs a dense pores and high tension.

scholarly journals Bovine Bone Hidroksiapatite Materials Mechanics Properties at 900°C and 1200°C of Calcination Temperature

2017 ◽  
Vol 16 (1) ◽  
Author(s):  
Antonius Adi Hendra Saputra ◽  
Joko Triyono ◽  
Teguh Triyono
Keyword(s):  
Compressive Strength ◽  
Calcination Temperature ◽  
Mechanical Characteristics ◽  
Bovine Bone ◽  
Scaffold Material ◽  
Temperature Variations ◽  
Bone Filler ◽  
Bovine Hydroxyapatite ◽  
The Difference

<p>The aims of this study is to determine the mechanical characteristics of the calcinated scaffold material bovine hydroxyapatite (BHA) for bone filler applications. Scaffold BHA was obtained from femur section of bovine bones which cut into 10x10x10 mm. Scaffold BHA was calcinated by temperature variations of 900ºC and 1200°C for 2 hours with 10ºC/min as the amount of the increasing level. The study result of each scaffold BHA which had been calcinated by 900°C and 1200°C has a hardness value of 8.48 ± 0.1118 VHN and 12.37 ± 0.5803, meanwhile the compressive strength value of each scaffold BHA samples is 3.03 ± 0.6764 MPa and 1.96 ± 0.3450 MPa. The porous on scaffold BHA samples calcinated by 900°C and 1200°C which had been observed by SEM had porous size that is not much different, it was ± 200-400 μm, the difference can be seen from the smaller porous size of the scaffold BHA calcination 1200°C compared to the porous size of scaffold BHA calcination 900°C.</p>

Investigating the weight ratio variation of alginate-hydroxyapatite composites for vertebroplasty method bone filler material

2017 ◽  
Author(s):  
Gusti Ruri Lestari ◽  
Akhmad Herman Yuwono ◽  
Nofrijon Sofyan ◽  
Ghiska Ramahdita
Keyword(s):  
Weight Ratio ◽  
Filler Material ◽  
Bone Filler ◽  
Ratio Variation

Production of Asbestos-free Brake Pad Using Groundnut Shell as Filler Material

2018 ◽  
Vol 4 (12) ◽  
Author(s):  
W. C. Solomon ◽  
M. T. Lilly ◽  
J. I. Sodiki
Keyword(s):  
Phenolic Resin ◽  
Cost Effective ◽  
Filler Material ◽  
Particle Sizes ◽  
Brake Pad ◽  
Brake Pads ◽  
Environmental Friendly ◽  
Sieve Size ◽  
Groundnut Shell ◽  
The Cost

The development and evaluation of brake pads using groundnut shell (GS) particles as substitute material for asbestos were carried out in this study. This was with a view to harnessing the properties of GS, which is largely deposited as waste, and in replacing asbestos which is carcinogenic in nature despite its good tribological and mechanical properties. Two sets of composite material were developed using varying particle sizes of GS as filler material, with phenolic resin as binder with percentage compositions of 45% and 50% respectively. Results obtained indicate that the compressive strength and density increase as the sieve size of the filler material decreases, while water and oil absorption rates increase with an increase in sieve size of GS particle. This study also indicates that the cost of producing brake pad can be reduced by 19.14 percent if GS is use as filler material in producing brake pad. The results when compared with those of asbestos and industrial waste showed that GS particle can be used as an effective replacement for asbestos in producing automobile brake pad. Unlike asbestos, GS-based brake pads are environmental friendly, biodegradable and cost effective.

Microbial Activity Evolution during the Acclimation of a Mixed Culture to Phenol: Use of CO2 Evolution Rate as Indicator

1992 ◽  
Vol 26 (9-11) ◽  
pp. 2049-2052 ◽  
Author(s):  
G. Buitrón ◽  
A. Koefoed ◽  
B. Capdeville
Keyword(s):  
Microbial Activity ◽  
Control Parameter ◽  
Sequencing Batch Reactor ◽  
Batch Reactor ◽  
Evolution Rate ◽  
Biodegradation Rate ◽  
Carbon Dioxide Evolution ◽  
Carbon Dioxide Evolution Rate ◽  
Infra Red ◽  
Negative Effect

The microbial activity during the aerobic acclimation of activated sludge to phenol was studied. Carbon dioxide evolution rate (CER), measured in a sequencing batch reactor coupled to an infra-red system, was utilized as the activity control parameter. It was found that CER is representative of the microbial metabolism. Moreover, it was observed that starvation periods during acclimation had a negative effect on biodegradation rate.

scholarly journals Evaluation of a bone filler scaffold for local antibiotic delivery to prevent Staphylococcus aureus infection in a contaminated bone defect

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Karen E. Beenken ◽  
Mara J. Campbell ◽  
Aura M. Ramirez ◽  
Karrar Alghazali ◽  
Christopher M. Walker ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Bone Defect ◽  
Rabbit Model ◽  
In Vivo Studies ◽  
Bovine Bone ◽  
Bone Filler ◽  
Antibiotic Release ◽  
Local Antibiotic ◽  
Antibiotic Delivery

AbstractWe previously reported the development of an osteogenic bone filler scaffold consisting of degradable polyurethane, hydroxyapatite, and decellularized bovine bone particles. The current study was aimed at evaluating the use of this scaffold as a means of local antibiotic delivery to prevent infection in a bone defect contaminated with Staphylococcus aureus. We evaluated two scaffold formulations with the same component ratios but differing overall porosity and surface area. Studies with vancomycin, daptomycin, and gentamicin confirmed that antibiotic uptake was concentration dependent and that increased porosity correlated with increased uptake and prolonged antibiotic release. We also demonstrate that vancomycin can be passively loaded into either formulation in sufficient concentration to prevent infection in a rabbit model of a contaminated segmental bone defect. Moreover, even in those few cases in which complete eradication was not achieved, the number of viable bacteria in the bone was significantly reduced by treatment and there was no radiographic evidence of osteomyelitis. Radiographs and microcomputed tomography (µCT) analysis from the in vivo studies also suggested that the addition of vancomycin did not have any significant effect on the scaffold itself. These results demonstrate the potential utility of our bone regeneration scaffold for local antibiotic delivery to prevent infection in contaminated bone defects.

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