scholarly journals Novel on-demand droplet generation for selective fluid sample extraction

2012 ◽  
Vol 6 (2) ◽  
pp. 024103 ◽  
Author(s):  
Robert Lin ◽  
Jeffery S. Fisher ◽  
Melinda G. Simon ◽  
Abraham P. Lee
2018 ◽  
Vol 30 (8) ◽  
pp. 084001 ◽  
Author(s):  
Keke Chen ◽  
Chenxi Sui ◽  
Yue Wu ◽  
Zheng Ao ◽  
Shi-shang Guo ◽  
...  
Keyword(s):  

Lab on a Chip ◽  
2019 ◽  
Vol 19 (3) ◽  
pp. 493-502 ◽  
Author(s):  
Hesam Babahosseini ◽  
Tom Misteli ◽  
Don L. DeVoe

A multifunctional microfluidic platform combining on-demand aqueous-phase droplet generation, multi-droplet storage, and controlled merging of droplets selected from a storage library in a single integrated microfluidic device is described.


2015 ◽  
Vol 9 (1) ◽  
pp. 014119 ◽  
Author(s):  
Uwe Tangen ◽  
Abhishek Sharma ◽  
Patrick Wagler ◽  
John S. McCaskill

Lab on a Chip ◽  
2020 ◽  
Vol 20 (21) ◽  
pp. 3914-3921
Author(s):  
Kirk Mutafopulos ◽  
Peter J. Lu ◽  
Ryan Garry ◽  
Pascal Spink ◽  
David A. Weitz

We generate traveling surface acoustic waves with an interdigital transducer to create droplets on-demand; encapsulate single cells; lyse cells and immediately encapsulate their contents; and pico-inject new materials into existing droplets.


2014 ◽  
Vol 8 (3) ◽  
pp. 034112 ◽  
Author(s):  
Minsoung Rhee ◽  
Peng Liu ◽  
Robert J. Meagher ◽  
Yooli K. Light ◽  
Anup K. Singh
Keyword(s):  

Author(s):  
Norbert Riefler ◽  
Thomas Wriedt ◽  
Udo Fritsching

The size of droplets generated by piezoelectric drop-on-demand (DOD) droplet generators can be varied to a cer-tain degree within one order of magnitude. This variation means that the droplet size is not solely determined by the nozzle diameter, and the droplet generation process is not restricted to drops extruded through a nozzle in conven- tional operation. By varying the electronic driving pulse, different droplet sizes can be obtained. To investigate the interaction of piezoelectric pulse excitation and the finally produced droplets, different approaches are applied. A comparison of a modal analysis of a pure piezo based on mechanical admittance calculations proofs the usability of electrical impedance measurements. This kind of measurements are then compared to finite-element simulations of a coupled piezo system – one as actuator, the other as pressure sensor – to extend the usable methods with the result that the fluid is of minor influence on the modal frequencies. Last, two phase fluid flow simulations with consequent pressure wave evaluations of the fluid show different pressure wave frequency specta than the modalanalysis.DOI: http://dx.doi.org/10.4995/ILASS2017.2017.4846


2009 ◽  
Vol 3 (5) ◽  
pp. 502-508 ◽  
Author(s):  
Yoko Yamanishi ◽  
◽  
Yuki Kihara ◽  
Shinya Sakuma ◽  
Fumihito Arai

We propose a hybrid polymer-metal magnetically driven microtool (MMT) featuring elasticity and rigidity. An electroplated magnetic metal axle is installed directly at the center of the MMT during molding. The result is a hybrid MMT whose fixed axes move elastically in a specific direction and whose center axle is rigid, preventing bending by unwanted external force. The axle’s higher magnetism contributes to powerful actuation. The hybrid MMT we designed provides on-demand droplet dispensation on chips. Its parallel plate is constrained translationally. Hybrid MMT displacement is 300 μm - 6 times greater than that of the conventional MMT. On-demand droplet generation produces a 177.7 ±2.3 μm droplet.


Lab on a Chip ◽  
2011 ◽  
Vol 11 (6) ◽  
pp. 1010 ◽  
Author(s):  
Sung-Yong Park ◽  
Ting-Hsiang Wu ◽  
Yue Chen ◽  
Michael A. Teitell ◽  
Pei-Yu Chiou

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