scholarly journals Cyclic olefin copolymer based microfluidic devices for biochip applications: Ultraviolet surface grafting using 2-methacryloyloxyethyl phosphorylcholine

2012 ◽  
Vol 6 (1) ◽  
pp. 012822 ◽  
Author(s):  
Rajeeb K. Jena ◽  
C. Y. Yue
Keyword(s):  
Microfluidic Devices ◽  
Surface Grafting ◽  
Cyclic Olefin Copolymer ◽  
Cyclic Olefin

Cyclic olefin copolymer as an X-ray compatible material for microfluidic devices

Lab on a Chip ◽  
2018 ◽  
Vol 18 (1) ◽  
pp. 171-178 ◽  
Author(s):  
Manuela Denz ◽  
Gerrit Brehm ◽  
Clément Y. J. Hémonnot ◽  
Heidi Spears ◽  
Andrew Wittmeier ◽  
...  
Keyword(s):  
Small Angle ◽  
Microfluidic Devices ◽  
Hot Embossing ◽  
Cyclic Olefin Copolymer ◽  
Cyclic Olefin ◽  
X Ray ◽  
X Ray Scattering ◽  
Ray Scattering

Fabrication of X-ray compatible microfluidic devices by hot embossing, and characterization for small angle X-ray scattering.

scholarly journals Cyclic Olefin Copolymer Microfluidic Devices for Forensic Applications

Biosensors ◽  
2019 ◽  
Vol 9 (3) ◽  
pp. 85 ◽  
Author(s):  
Brigitte Bruijns ◽  
Andrea Veciana ◽  
Roald Tiggelaar ◽  
Han Gardeniers
Keyword(s):  
Chemical Resistance ◽  
Multiple Displacement Amplification ◽  
Visible Region ◽  
Dna Amplification ◽  
Microfluidic Devices ◽  
Cyclic Olefin Copolymer ◽  
Color Test ◽  
Cyclic Olefin ◽  
On Chip ◽  
Amplification Reaction

Microfluidic devices offer important benefits for forensic applications, in particular for fast tests at a crime scene. A large portion of forensic applications require microfluidic chip material to show compatibility with biochemical reactions (such as amplification reactions), and to have high transparency in the visible region and high chemical resistance. Also, preferably, manufacturing should be simple. The characteristic properties of cyclic olefin copolymer (COC) fulfills these requirements and offers new opportunities for the development of new forensic tests. In this work, the versatility of COC as material for lab-on-a-chip (LOC) systems in forensic applications has been explored by realizing two proof-of-principle devices. Chemical resistance and optical transparency were investigated for the development of an on-chip presumptive color test to indicate the presence of an illicit substance through applying absorption spectroscopy. Furthermore, the compatibility of COC with a DNA amplification reaction was verified by performing an on-chip multiple displacement amplification (MDA) reaction.

scholarly journals Fast Fabrication Process of Microfluidic Devices Based on Cyclic Olefin Copolymer

2014 ◽  
Vol 29 (2) ◽  
pp. 93-99 ◽  
Author(s):  
Aymen Ben Azouz ◽  
Stephen Murphy ◽  
Shadi Karazi ◽  
Mercedes Vázquez ◽  
Dermot Brabazon
Keyword(s):  
Microfluidic Devices ◽  
Fabrication Process ◽  
Cyclic Olefin Copolymer ◽  
Cyclic Olefin

Rapid prototyping of plastic microfluidic devices in cyclic olefin copolymer (COC)

2005 ◽  
Author(s):  
Jin-Hwan Lee ◽  
Erik T. K. Peterson ◽  
Gabriel Dagani ◽  
Ian Papautsky
Keyword(s):  
Rapid Prototyping ◽  
Microfluidic Devices ◽  
Cyclic Olefin Copolymer ◽  
Cyclic Olefin

Effects of Fabrication Process Parameters on the Properties of Cyclic Olefin Copolymer Microfluidic Devices

2006 ◽  
Vol 15 (5) ◽  
pp. 1060-1068 ◽  
Author(s):  
C.K. Fredrickson ◽  
Z. Xia ◽  
C. Das ◽  
R. Ferguson ◽  
F.T. Tavares ◽  
...  
Keyword(s):  
Process Parameters ◽  
Microfluidic Devices ◽  
Fabrication Process ◽  
Cyclic Olefin Copolymer ◽  
Cyclic Olefin
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