Dynamic double layer model: Description of time dependent charging phenomena in insulators under electron beam irradiation

1995 ◽  
Vol 78 (10) ◽  
pp. 6224-6232 ◽  
Author(s):  
A. Melchinger ◽  
S. Hofmann
Author(s):  
Fuzhi Lu ◽  
Daniel Y. Kwok

We developed a 2D electric double layer model for biological nanochannels based on the linearlized Poisson-Boltzmann equation with arbitrary surface potential. Time dependent adsorption kinetics was used in the model to examine the variation of electric double layer distribution and compare with that from the classical model. Based on the 2D model, EDL interaction for heavily patched arbitray surface potential was found to be much weaker in such biological nanochannels. Channel end effects are also found to be significant and not negligible.


2008 ◽  
Vol 104 (12) ◽  
pp. 124904 ◽  
Author(s):  
Masaaki Yasuda ◽  
Yasuaki Kainuma ◽  
Hiroaki Kawata ◽  
Yoshihiko Hirai ◽  
Yasuhiro Tanaka ◽  
...  

Author(s):  
B. L. Armbruster ◽  
B. Kraus ◽  
M. Pan

One goal in electron microscopy of biological specimens is to improve the quality of data to equal the resolution capabilities of modem transmission electron microscopes. Radiation damage and beam- induced movement caused by charging of the sample, low image contrast at high resolution, and sensitivity to external vibration and drift in side entry specimen holders limit the effective resolution one can achieve. Several methods have been developed to address these limitations: cryomethods are widely employed to preserve and stabilize specimens against some of the adverse effects of the vacuum and electron beam irradiation, spot-scan imaging reduces charging and associated beam-induced movement, and energy-filtered imaging removes the “fog” caused by inelastic scattering of electrons which is particularly pronounced in thick specimens.Although most cryoholders can easily achieve a 3.4Å resolution specification, information perpendicular to the goniometer axis may be degraded due to vibration. Absolute drift after mechanical and thermal equilibration as well as drift after movement of a holder may cause loss of resolution in any direction.


Sign in / Sign up

Export Citation Format

Share Document