scholarly journals Mesoscopic Properties of Molecular Folding and Aggregation Processes

2008 ◽  
Author(s):  
Michael Bachmann ◽  
Wolfhard Janke ◽  
Jesús Clemente-Gallardo ◽  
Pierpaolo Bruscolini ◽  
Francisco Castejón ◽  
...  
Keyword(s):  
Aggregation Processes ◽  
Molecular Folding

Role of the Structural Characteristics of Dendrimers in the Manifestation of the Antiamyloid Properties

INEOS OPEN ◽  
2020 ◽  
Vol 3 ◽  
Author(s):  
S. A. Sorokina ◽  
◽  
Yu. Yu. Stroilova ◽  
V. I. Muronets ◽  
Z. B. Shifrina ◽  
...  
Keyword(s):  
Neurodegenerative Diseases ◽  
Structural Characteristics ◽  
Short Review ◽  
External Factors ◽  
Amyloid Aggregation ◽  
Amyloid Proteins ◽  
Molecular Parameters ◽  
Amyloid Aggregates ◽  
Aggregation Processes

Among the compounds able to efficiently inhibit the amyloid aggregation of proteins and decompose the amyloid aggregates that cause neurodegenerative diseases, of particular interest are dendrimers, which represent individual macromolecules with the hypercrosslinked architectures and given molecular parameters. This short review outlines the peculiarities of the antiamyloid activity of dendrimers and discusses the effect of dendrimer structures and external factors on their antiamyloid properties. The potential of application of dendrimers in further investigations on the aggregation processes of amyloid proteins as the compounds that exhibit the remarkable antiamyloid activity is evaluated.

INFLUENCE OF MAGNETIC NANOPARTICLES ON ACOUSTIC ATTENUATION IN LIQUIDS

Akustika ◽  
2020 ◽  
pp. 8-13
Author(s):  
Štefan Hardoň ◽  
Jozef Kúdelčík
Keyword(s):  
Magnetic Nanoparticles ◽  
Heat Exchangers ◽  
Magnetic Fluids ◽  
Magnetic Flux Density ◽  
Acoustic Attenuation ◽  
Cooling Systems ◽  
Practical Applications ◽  
Acoustic Spectroscopy ◽  
Aggregation Processes ◽  
Diagnostics And Therapy

Magnetic fluids with nanoparticles dispersed in water or oils offer attractive applications in biomedicine and industry. Biocompatible magnetic fluids are used for diagnostics and therapy in medical applications, in pharmacy, and biosensors. Application of ferrofluids is expanding into energy conservation, faster and efficient cooling, and hence better performance in a wide variety of practical applications (in heat exchangers, mainly in micro-cooling systems). For the study of the influence of an external magnetic field on the aggregation processes of magnetic nanoparticles in magnetic fluids, acoustic spectroscopy was used. The jump changes of the magnetic flux density at various temperatures influenced the acoustic attenuation. The measured changes were results of nanoparticle aggregations into new structures.

scholarly journals A New Approach to Obtaining Nano-Sized Graphene Oxide for Biomedical Applications

Materials ◽  
2021 ◽  
Vol 14 (6) ◽  
pp. 1327
Author(s):  
Paulina Bolibok ◽  
Bartosz Szymczak ◽  
Katarzyna Roszek ◽  
Artur P. Terzyk ◽  
Marek Wiśniewski
Keyword(s):  
Graphene Oxide ◽  
Biomedical Applications ◽  
Effective Concentration ◽  
New Approach ◽  
Spectral Changes ◽  
Dimethyl Sulfoxide Solution ◽  
Aggregation Processes ◽  
Initial Oxygen ◽  
Half Maximal Effective Concentration ◽  
Nano Size

Graphene oxide (GO) is one of the most exciting and widely used materials. A new method of nanographene oxide (n-GO) formation is presented. The described unique sequence of ultrasonication in dimethyl sulfoxide solution allows us to obtain different sizes of n-GO sheets by controlling the timing of the cutting and re-aggregation processes. The obtained n-GO exhibits only minor spectral changes, mainly due to the formation of S-containing surface groups; thus, it can be concluded that the material is not reduced during the process. Maintaining the initial oxygen functionalities together with the required nano-size (down to 200 nm) and high homogeneity are beneficial for extensive applications of n-GO. Moreover, we prove that the obtained material is evidently biocompatible. The calculated half-maximal effective concentration (EC50) increases by 5-fold, i.e., from 50 to 250 µg/mL, when GO is converted to n-GO. As a consequence, the new n-GO neither disturbs blood flow even in the narrowest capillaries nor triggers a toxic influence in surrounding cells. Thus, it can be a serious candidate for drugs and biomolecule carriers administered systemically.

scholarly journals A Novel Use of Honey’s Aggregation Approach to the Analysis of Repertory Grids

Field Methods ◽  
2018 ◽  
Vol 31 (2) ◽  
pp. 150-166 ◽  
Author(s):  
Céline Rojon ◽  
Almuth McDowall ◽  
Mark N. K. Saunders
Keyword(s):  
Implicit Theories ◽  
Personal Construct ◽  
Workplace Performance ◽  
Individual Level ◽  
Repertory Grids ◽  
Novel Approach ◽  
Aggregation Processes ◽  
Grid Technique ◽  
Data Granularity ◽  
Constructivist Epistemology

This article examines and appraises a novel approach for generating shared group constructs through aggregative analysis: the application of Honey’s aggregation procedure to repertory grid technique (RGT) data. Revisiting personal construct theory’s underlying premises and adopting a social constructivist epistemology, we argue that, while “implicit theories” of the world, elicited via RGT, are unique to individuals, the constructs on which they are founded may be shared collectively. Drawing on a study of workplace performance, we outline a protocol for this novel use of Honey’s approach, demonstrating how it can be utilized to generate shared constructs inductively to facilitate theory building. We argue that, unlike other grid aggregation processes, the approach does not compromise data granularity, offering a useful augmentation to traditional idiographic approaches examining individual-level constructs only. This approach appears especially suited to addressing complex and implicit topics, where individuals struggle to convey thoughts and ideas.

Focus on the aggregation processes of Photosystem II complexes

2007 ◽  
Vol 70 (1) ◽  
pp. 33-38 ◽  
Author(s):  
A. Ventrella ◽  
L. Catucci ◽  
V. Villari ◽  
L. Monsù Scolaro ◽  
A. Agostiano
Keyword(s):  
Photosystem Ii ◽  
Aggregation Processes

Two-species aggregation processes with migration

2004 ◽  
Vol 325 (1) ◽  
pp. 9-15 ◽  
Author(s):  
Jianhong Ke ◽  
Youyi Zhuang ◽  
Zhenquan Lin
Keyword(s):  
Aggregation Processes
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