Proton Magnetic Resonance of Simple Amino Acids and Dipeptides in Aqueous Solution

1957 ◽  
Vol 26 (5) ◽  
pp. 1346-1347 ◽  
Author(s):  
Masatami Takeda ◽  
Oleg Jardetzky
Keyword(s):  
Aqueous Solution ◽  
Amino Acids ◽  
Magnetic Resonance ◽  
Proton Magnetic Resonance

The preparation of 2-Fluoro-5-nitrobenzonitrile and the proton magnetic resonance spectra of some compounds containing the N-(2-Cyano-4-nitrophenyl) group

1967 ◽  
Vol 20 (8) ◽  
pp. 1663 ◽  
Author(s):  
JFK Wilshire
Keyword(s):  
Amino Acids ◽  
Magnetic Resonance ◽  
Nitro Group ◽  
Proton Magnetic Resonance ◽  
Cyano Group ◽  
Aromatic Nucleus ◽  
Heteroaromatic Compounds ◽  
Magnetic Resonance Spectra

2-Fluoro-5-nitrobenzonitrile, an analogue of 1-fluoro-2,4- dinitrobenzene, in which the 2-nitro group has been replaced by a cyano group, has been prepared and made to react with several amines, amino acids, and NH-heteroaromatic compounds. The proton magnetic resonance spectra of some of the resultant N-(2-cyano-4-nitrophenyl) derivatives were compared with the spectra of the corresponding N-(2,4- dinitrophenyl) derivatives and furnish further evidence that the ortho nitro group of the latter derivatives is rotated out of the plane of the aromatic nucleus.

Ribo-2′-deoxyribo hybrid dinucleoside monophosphates. Proton magnetic resonance studies of 3′,5′- and 2′,5′-uridylyl-2′-deoxythymidine

1978 ◽  
Vol 56 (4) ◽  
pp. 522-529 ◽  
Author(s):  
James Peeling ◽  
Frank E. Hruska ◽  
Peter C. Loewen
Keyword(s):  
Aqueous Solution ◽  
Magnetic Resonance ◽  
Proton Magnetic Resonance ◽  
Molecular Conformation ◽  
The Other ◽  
Magnetic Resonance Studies ◽  
Dinucleoside Monophosphates ◽  
Standard Techniques

This 1Hmr study initiates our examination of the conformations of dinucleoside monophosphates possessing ribo 2′- or 3′-nucleotidyl units linked to 5′-nucleotidyl units possessing the 2′-deoxyribo sugar. The syntheses of uridylyl-3′,5′-2′-deoxythymidine (3′,5′-UpdT) and its 2′,5′-isomer, 2′,5′-UpdT, were carried out with standard techniques. The 1Hmr data were obtained at frequencies up to 270 MHz and used to derive the dominant conformation of the dimers in aqueous solution. Comparison with data for the component mononucleotides reveals that dimerization does not lead to drastic changes in the molecular conformation. Literature data for dimers possessing only the ribo sugar (3′,5′-UpU) and the 2′-deoxyribo sugar (3′,5′-d(TpT)) are also presented. The results indicate that, at least for our dipyrimidine dimers, the molecular conformation of a particular fragment is not critically dependent on the nature (ribo or 2′-deoxyribo) of the other nucleotide unit.

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