Simple Conversion of the Beckman IR‐4 Recording Spectrophotometer Chart Bed to Use Small Chart Paper

1961 ◽  
Vol 32 (2) ◽  
pp. 220-221
Author(s):  
Robert Humphry
1977 ◽  
Vol 37 (03) ◽  
pp. 535-540 ◽  
Author(s):  
D. S Pepper ◽  
D Banhegyi ◽  
Ann Howie

SummaryPrevious work from this department, concerned with testing the potential thrombogenicity of therapeutic factor IX concentrates, demonstrated that following recalcification of factor IX concentrates thrombin was generated within 3-30 minutes of incubation (Sas et al. 1975). The test developed (known as the TGt 50 test) is a two-stage assay and was thus found to be time consuming, tedious and tended to become inaccurate with long incubation periods and a large number of samples. A semiautomatic version of the test is reported in which the synthetic peptide Bz-ILE-GLU-GLY-ARG-pNA (S-2222) is added to recalcified, diluted factor IX concentrate in the micro-cuvette of a multiple sample recording spectrophotometer. Information can be obtained on (a) the amount of Xa (if any) present prior to recalcification (b) the initial amount of Xa formed and (c) the time taken to activate all factor X to Xa. Direct graphical interpretation shows a number of qualitative differences between commercial preparations, but by either of the criteria (b) or (c) above, it is possible to place the different products into “activated” and “non activated” groups such that both the Xa generation times and TGt 50 tests identify the same two groups of products. This agreement also indicates that the TGt 50 test is independent of the intrinsic factor V levels in the various concentrates.


Genetics ◽  
1996 ◽  
Vol 143 (1) ◽  
pp. 129-136 ◽  
Author(s):  
Frederick J Bowring ◽  
David E A Catcheside

Abstract We have used closely flanking molecular markers located ~4 kb distal and 6 kb proximal of the am locus to investigate the incidence of crossover events associated with the generation of prototrophic recombinants in a cross heteroallelic am1 am6. Ninety-three percent of prototrophs were generated by events that did not recombine the molecular markers, indicating that simple conversion accounts for the formation of most prototrophs and that associated crossovers are much less frequent (~0.07) than estimated previously using more distant flanking markers. This suggests that conversion and crossing over during meiosis may arise from distinct mechanisms or that if, as is widely supposed, conversion and crossing over result from alternate modes of resolution of Holliday junctions then, at least for the am locus of Neurospora, the mode of resolution is strongly biased in favor of retaining the parental association of flanking sequences. Because estimates of the association of conversion and crossing over based on more distant gene markers are similar for yeast and Neurospora (~0.35), our observation may have general significance.


Author(s):  
Elaiyappillai Elanthamilan ◽  
Arumugam Ganeshkumar ◽  
Aravind Radha ◽  
Rajendran Rajaram ◽  
Johnson Princy Merlin

1973 ◽  
Vol 12 (12) ◽  
pp. 2872 ◽  
Author(s):  
A. R. Robertson ◽  
W. Budde ◽  
F. T. McNeely

Brodogradnja ◽  
2021 ◽  
Vol 72 (3) ◽  
pp. 81-95
Author(s):  
Špiro Ivošević ◽  
◽  
Nataša Kovač ◽  
Nikola Momčilović ◽  
Goran Vukelić ◽  
...  

To ensure the better structural integrity and maximum safety of bulk carriers in the ship design phase, an appropriate corrosion margin is introduced by the classification societies, which should enable the exploitation of ships during the projected 25-year life cycle. The new Common Structural Rules introduce even higher corrosion margin value to ensure the structural integrity of the ship. This directly affects the increase in hull weight and thus the need for more total installed power and higher fuel consumption. Higher fuel consumption results in increased emissions which directly affects environmental pollution. For these reasons, efforts are being made to introduce alternative energy sources, cleaner fuel, ship weight reduction, and the overall economic efficiency of ships. Therefore, using experimental data collected on aging bulk carriers, the paper explores the corrosion margin reduction potential considering its impact on hull weight. Assuming that the corrosive processes occur after four years of operation, a linear model that describes the percentage of plate wear as a function of the as build-in the thickness of inner bottom plates (IBP) of fuel oil tanks (FOT) located on the double bottom of aging bulk carriers, is analyzed. Over the course of 25 years, the IBP segment was monitored on 36 different ships surveys. In this way, 520 input data describing the depth of corrosion were formed. At the same time, records were kept on the mean thickness of the original metal plate, which enabled systematization of the empirical database and grouping of measured values by intervals of original plate thicknesses, and simple conversion of corrosion depth into adequate percentage values. Depth corrosion percentages were represented by standard linear models known in the literature. Based on this analysis, representative numerical and graphical results were obtained. Conclusions from the paper can assist to optimize corrosion margin and the energy efficiency of future vessels.


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