A parallel-detection frequency-domain near-infrared tomography system for hemoglobin imaging of the breast in vivo

2001 ◽  
Vol 72 (3) ◽  
pp. 1817 ◽  
Author(s):  
Troy O. McBride ◽  
Brian W. Pogue ◽  
Shudong Jiang ◽  
Ulf L. Österberg ◽  
Keith D. Paulsen
Keyword(s):  
Frequency Domain ◽  
Near Infrared ◽  
Parallel Detection ◽  
Tomography System ◽  
Detection Frequency ◽  
Infrared Tomography

MR-GUIDED PULSE OXIMETRY IMAGING OF BREAST IN VIVO

2011 ◽  
Vol 04 (02) ◽  
pp. 199-208
Author(s):  
ZHIQIU LI ◽  
SHUDONG JIANG ◽  
VENKATARAMANAN KRISHNASWAMY ◽  
SCOTT C. DAVIS ◽  
SUBHADRA SRINIVASAN ◽  
...  
Keyword(s):  
Breast Tissue ◽  
Near Infrared ◽  
Imaging System ◽  
Structural Information ◽  
Human Subjects ◽  
Nir Spectroscopy ◽  
Tomography System ◽  
Finger Pulse ◽  
Lock In

A near-infrared (NIR) tomography system with spectrally-encoded sources in two wavelength bands was built to quantify the temporal oxyhemoglobin and deoxyhemoglobin contrast in breast tissue at a 20 Hz bandwidth. The system was integrated into a 3 T magnetic resonance (MR) imaging system through a customized breast coil interface for simultaneous optical and MRI acquisition. In this configuration, the MR images provide breast tissue structural information for NIR spectroscopy of adipose and fibro-glandular tissue in breast. Spectral characterization performance of the NIR system was verified through dynamic phantom experiments. Normal human subjects were imaged with finger pulse oximeter (PO) plethysmogram synchronized to the NIR system to provide a frequency-locked reference. Both the raw data from the NIR system and the recovered absorption coefficients of the breast at two wavelengths showed the same frequency of about 1.3 Hz as the PO output. The frequency lock-in approach provided a practical platform for MR-localized recovery of small pulsatile variations of oxyhemoglobin and deoxyhemoglobin in the breast, which are related to the heartbeat and vascular resistance of the tissue.

Developments in Quantitative Oxygen-Saturation Imaging of Breast Tissue In Vivo Using Multispectral Near-Infrared Tomography

2007 ◽  
Vol 9 (8) ◽  
pp. 1143-1156 ◽  
Author(s):  
Subhadra Srinivasan ◽  
Brian W. Pogue ◽  
Colin Carpenter ◽  
Shudong Jiang ◽  
Wendy A. Wells ◽  
...  
Keyword(s):  
Oxygen Saturation ◽  
Breast Tissue ◽  
Near Infrared ◽  
Infrared Tomography

High frame-rate MR-guided near-infrared tomography system to monitor breast hemodynamics

2011 ◽  
Author(s):  
Zhiqiu Li ◽  
Shudong Jiang ◽  
Venkataramanan Krishnaswamy ◽  
Scott C. Davis ◽  
Subhadra Srinivasan ◽  
...  
Keyword(s):  
Near Infrared ◽  
Frame Rate ◽  
High Frame Rate ◽  
Tomography System ◽  
Infrared Tomography

In Vivo Imaging of Pressure Effects in Normal Breast Tissue with Quantitative Multi-Spectral Near-Infrared Tomography

2004 ◽  
Author(s):  
Shudong Jiang ◽  
Brian W. Pogue ◽  
Xiaomei Song ◽  
Subhadra Srinivasan ◽  
Keith D. Paulsen ◽  
...  
Keyword(s):  
In Vivo Imaging ◽  
Breast Tissue ◽  
Near Infrared ◽  
Normal Breast Tissue ◽  
Normal Breast ◽  
Pressure Effects ◽  
Infrared Tomography

Magnetic-resonance-imaging–coupled broadband near-infrared tomography system for small animal brain studies

2005 ◽  
Vol 44 (11) ◽  
pp. 2177 ◽  
Author(s):  
Xu Heng ◽  
Roger Springett ◽  
Hamid Dehghani ◽  
Brian W. Pogue ◽  
Keith D. Paulsen ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Near Infrared ◽  
Small Animal ◽  
Resonance Imaging ◽  
Animal Brain ◽  
Tomography System ◽  
Infrared Tomography

In vivo determination of the optical properties of infant brain using frequency-domain near-infrared spectroscopy

2005 ◽  
Vol 10 (2) ◽  
pp. 024028 ◽  
Author(s):  
Jun Zhao ◽  
Hai Shu Ding ◽  
Xin Lin Hou ◽  
Cong Le Zhou ◽  
Britton Chance
Keyword(s):  
Optical Properties ◽  
Infrared Spectroscopy ◽  
Frequency Domain ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Infant Brain

Approximation of Mie scattering parameters in near-infrared tomography of normal breast tissue in vivo

2005 ◽  
Vol 10 (5) ◽  
pp. 051704 ◽  
Author(s):  
Xin Wang ◽  
Brian W. Pogue ◽  
Shudong Jiang ◽  
Xiaomei Song ◽  
Keith D. Paulsen ◽  
...  
Keyword(s):  
Breast Tissue ◽  
Near Infrared ◽  
Normal Breast Tissue ◽  
Mie Scattering ◽  
Normal Breast ◽  
Scattering Parameters ◽  
Infrared Tomography

Image reconstruction of effective Mie scattering parameters of breast tissue in vivo with near-infrared tomography

2006 ◽  
Vol 11 (4) ◽  
pp. 041106 ◽  
Author(s):  
Xin Wang ◽  
Brian W. Pogue ◽  
Shudong Jiang ◽  
Hamid Dehghani ◽  
Xiaomei Song ◽  
...  
Keyword(s):  
Image Reconstruction ◽  
Breast Tissue ◽  
Near Infrared ◽  
Mie Scattering ◽  
Scattering Parameters ◽  
Infrared Tomography
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